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Cellular based biology explanation of sex bias in ARDs 👀
Data from AMP w/ sc-RNA seq from synovial tissue shows:
Enriched inflammatory pathways in females synovial macrophages clusters vs. males
Basis for gender specific treatment strategies?
@RheumNow ABST0724 #ACR23 https://t.co/1p8PDIRNoI
Aurelie Najm ( View Tweet)
Abs#0726 #ACR23 @RheumNow
MSUS recs in Canadian Rheum training 🇨🇦:
Focus MSUS exam of hands/wrists/feet: ID effusion, synov, erosions v osteophyte, tenosyn
Limited MSUS of knee/ankle for effusion
@USSONAR_Rh @MymaAlbaydaMD
Agree: MSUS should be part of rheum training for all https://t.co/UNPpAA1p0V
Eric Dein ( View Tweet)
Real world data on low dose PEXIVAS steroid by Nagle et al. Increased risk of progression/relapse/death/ESKD in those with severe GPA/MPA HR 1.72. More marked in those with creat>300 or with RTX induction Abstr#0725 #ACR23 @RheumNow https://t.co/vTXVZfjbXx https://t.co/4FuMjxOuyB
Richard Conway ( View Tweet)
#ACR23 Abs 0465 suggests changes in rheums’ rx patterns in context of nationwide abortion restriction, particularly in abortion-restricted states; reproductive-age female pts may have less access to EB treatments like MTX/MMF for rheum dz. https://t.co/QN9C4PjUaN
@rheumnow
Dr. Rachel Tate ( View Tweet)
These US Medicare data show us what we've all suspected:
PMR patients stuck on steroid get the fractures, heart attacks, & infections that land them in hospital.
And it costs $$$
Hopefully PMR steroid-sparing Rx can change this!
@RADoctor @SattuiSEMD #ACR23 ABST0718 @RheumNow https://t.co/XAWmf2qZAU
David Liew drdavidliew ( View Tweet)
Dr. Arbeeva explains how a "modern diet" can lead to MetS, intestinal dysbiosis & obesity - risk factors assoc w/ development of #osteoarthritis
Modern diet:
⬆️calorie processed food
⬇️proportion of fruits & veggies
⬆️ratio of omega-6 FA:omega-3FA
#ACR23 @rheumnow @rheumarhyme https://t.co/biVSE103S0
sheila ( View Tweet)
#ACR23 Memorable Quote as reminded to us by Dr. P Seo during Year in Review:
"What you think of as a rare manifestation of a common disease is probably a common presentation of a disease you are not aware of (yet)!"
- Prof Seza Zen, MD
@RheumNow https://t.co/Xhwb1brLKG
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Which to use in #EGPA? #Mepolizumab IL5i vs Benralizumab = monoclonal Ab binding to IL5Ralpha. Noninferiority RCT - both are similar. Is more Impt ? IL5 drug vs #Rituximab or #Cyclo for severe Eosinoph granuloma todos w polyangiitis 🤷 #ACR23 @RheumNow @ACRheum https://t.co/zyZeHHSsck
Janet Pope ( View Tweet)
We gotta do better! Reproductive health counseling is poorly done- only a third rheumatologists surveyed ask pts about reproductive health: sexual activity, pregnancy desire, contraception. Abstr#0162 @_michgarcia @rheumnow #ACR23 https://t.co/r9tewu2I9N
TheDaoIndex KDAO2011 ( View Tweet)
Join us tonight at 6pm PT/ 9pm ET for our daily #ACR23 recap. https://t.co/0RDwTdzhwS
Dr. John Cush RheumNow ( View Tweet)
AI is here to stay, like it or not.
Some words to ponder on👇
#ACR23 @RheumNow @rheumarhyme https://t.co/2K3Qc0Il8i
sheila ( View Tweet)
Low uptake of Artificial intelligence in Medicine! This needs to change. Keynote speaker #ACR23 @RheumNow https://t.co/gOTu1wBnZS
Bella Mehta bella_mehta ( View Tweet)
"Machines don't decide, they make predictions..-Dr. Avi Goldfarb
As a parting note, he leaves the audience some Qs: "In your orgs/institutions, how much of what you do is really about delivering value? Or serving patients & other stakeholders?"
#ACR23 @RheumNow @rheumarhyme https://t.co/xnFeQgDPco
sheila ( View Tweet)
This is what exactly what AI should mean for clinical rheumatologists:
discard the mundane & repetitive
enhance/make time the value add
Rheumatologists are really good at the value add, and we dislike the mundane & repetitive. We should embrace what is to come.
#ACR23 @RheumNow https://t.co/6Lb2ihlPFF
David Liew drdavidliew ( View Tweet)
Does the weather affect synovitis? Abstract this suggested so! Low wind speed & temp rise associated w/joint u/s findings in a large prospectove cohort
Full disclosure: I'm super skeptical of this, whole lotta p values. Still, love "fun" science😂🤣
@RheumNow #ACR23 Abstr407 https://t.co/JkqdUbM8YK
Mike Putman EBRheum ( View Tweet)
Understanding placebo effects is very important for any clinical research! This book will lay down important concepts in this. And fully accessible in a few weeks!
@RheumNow #ACR23 https://t.co/J3grEhP460
Bella Mehta bella_mehta ( View Tweet)
Little disturbing to see the data that most patients using cannabis dont know what exact product they are using. Also not most is not prescribed/ illegal!
Lots to learn and may have potential but need to be careful!
@RheumNow #ACR23 https://t.co/Y0vHmVvWdL
Bella Mehta bella_mehta ( View Tweet)
Type III relapsing polychondritis has the MAGIC and VEXAS groups, with genital ulcers and haematological manifestations, 8% of RP patients have VEXAS, Ferrada M, #ACR23 @RheumNow https://t.co/FsmBK0F7ZD
Dr. Antoni Chan ( View Tweet)
Relapsing polychondritis RP is a systemic condition and not just inflammation in the ears 👂 Ferrara M #ACR23 @RheumNow https://t.co/BXvyWYMYa0
Dr. Antoni Chan ( View Tweet)
Recombinant ADAMTS13 therapy just @US_FDA approved - will save these patients recurrent plasma infusions (every couple of weeks for months), a big win.
https://t.co/lKdWTMp2oc
#ACR23 Review Course @RheumNow https://t.co/2NMbJvseiA
David Liew drdavidliew ( View Tweet)
