Do You Zoster Vaccinate? (6.19.2026)
Dr. Jack Cush reviews the news, journal reports and best ways to review EULAR 2026.
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CAR-T Cell Therapies at EULAR 2026
EurekAlert!
In an oral abstract presentation on Wednesday 3rd June, Fredrik Albach presented results for mivocabtagene autoleucel – an autologous, fully human CD19-directed CAR-T cell therapy – from Phase 1 of the prospective, open-label COMPARE trial in six patients with anti-
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EULAR26 Insights into Gout and Obesity
EurekAlert!
New EULAR 2026 data show continued treat-to-target ULT beats a discontinuation strategy for maintaining gout remission (79.2% vs. 62.9% flare-free), though many who stopped still stayed flare-free. A companion study links gout and rheumatoid arthritis to distinct, adverse body fat patterns tied
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A Disease Seeking Its Identity: Peripheral SpA, PsA, and the SPARTACUS Evidence
For years, peripheral spondyloarthritis has been managed with a cautious, stepwise approach: start with NSAIDs, escalate to conventional synthetic DMARDs, and only reach for biologics when everything else fails. The SPARTACUS trial, presented at EULAR 2026 in London, challenges that paradigm
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EULAR 2026: Updated Recommendations for Vaccination in Patients with Autoimmune Inflammatory Rheumatic Diseases
This update includes new pandemic era evidence, recombinant zoster vaccine data, and new perspectives on vaccination in patients taking novel immunosuppressants. Five overarching principles and 10 vaccine recommendations follow.
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Late-Breaking Studies at EULAR 2026
MedPage Today
Late-breaking abstracts presented at the European Alliance of Associations for Rheumatology's (EULAR) annual meeting, held here last week, addressed a wide range of clinical
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Danish hospital 574 newly diagnosed RA pt, 75% recv glucocorticoids (GC) in 1st yr (55% 1st visit) -- mean dose was 9.3 mg/day, with 46% recv oral tablets & 47% IA steriods injections. 20% had an infection in 1st Yr (RR 1.13; 0.77 to 1.67). Doses declined after 1st visit, but not https://t.co/JcerD61m0t
Dr. John Cush @RheumNow( View Tweet )
MTX: SC vs Oral? Metanalysis of 9 RCTs, 974 RA pts. Compared w/ oral, SC MTX signif. incr odds of ACR20 (RR=1.15), ACR50 (RR=1.14) & reduced GI adverse events (RR=0.58), diarrhea (RR=0.42): BUT no difference in ACR70, DAS28-ESR, bioavailability AUC, or other AE https://t.co/tQeQz7H7do
Dr. John Cush @RheumNow( View Tweet )
Increased VTE Risk with Baricitinib
The RA-BRIDGE and RA-BRANCH studies were presented as a late-breaking abstract at EULAR 2026. This was the pooled results from two large FDA post-marketing commitment safety trials — RA-BRIDGE (global) and RA-BRANCH (US-only) — comparing baricitinib at 2 mg and 4 mg daily against TNF
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True or False: Current guidelines for peripheral SpA recommend initiating treatment with TNF inhibitors before trying NSAIDs or conventional synthetic DMARDs. See if you got it right in this week's RheumIQ quiz at https://t.co/6uiqJjYUVo https://t.co/9hHFjaGUdt
Dr. John Cush @RheumNow( View Tweet )
Obinutuzumab drives histologic remission in lupus nephritis
At #EULAR2026, new data from the phase III REGENCY trial add to the case for obinutuzumab in lupus nephritis. Investigators report deep intrarenal B-cell depletion and significantly higher rates of histological https://t.co/13HY1qIDcj
Dr. John Cush @RheumNow( View Tweet )
Vasculitis Updates: Glucocorticoid use in AAV and GCA
Vasculitis Updates: Glucocorticoids are the cornerstone of initial therapy for AAV and GCA—quickly reducing inflammation and preserving organs. EULAR has issued recommendations on glucocorticoid use in ANCA‑associated and https://t.co/hIOKyXDxyb
Dr. John Cush @RheumNow( View Tweet )
EULAR 2026 Rheumatology RoundUp
It’s time for Rheumatology RoundUp from EULAR 2026 from London, UK. Drs. Artie Kavanaugh and Jack Cush review their choice presentations from the meeting, offering their perspectives on impact and applicability.
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When Patients with RA Choose Their Treatment, Outcomes Are Better — Here's the Data
Dr. Aurelie Najm discusses abstract OP0204 presented in London at the EULAR 2026 Congress.
https://t.co/hHQFffTXH0 https://t.co/tXv0SnGBz1
Dr. John Cush @RheumNow( View Tweet )
NK Cells Without a CAR: AB-101 Is Neither CAR-T nor CAR-NK
Much of the meeting came for the next CAR T readout. AB-101 drew attention for a different reason. It depletes B cells by a completely different route.
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Strike First: TNFi vs. Step-Up Therapy in Early Peripheral SpA
The approach to treating peripheral SpA has remained the same for a long time. The guidelines recommend starting with NSAIDs, escalating to conventional synthetic DMARDs, typically sulfasalazine or methotrexate, and https://t.co/iEqzp6FStv
Dr. John Cush @RheumNow( View Tweet )
Three Abstracts That May Shape the Future of RA Treatment
Our therapeutic armamentarium in RA keeps on growing. New studies and new molecules, new mechanisms of action or new ways of using old drugs are presented every year at conferences. But which are the ones who can have an https://t.co/CaMSHlkbFD
Dr. John Cush @RheumNow( View Tweet )
Hot topic: menopause and inflammatory arthritis outcomes in RA and PsA
Across EULAR 2026 abstracts this year and presented in a session called “this is a woman’s world”, strong signals are emerging that the menopausal transition is associated with changes in disease phenotype, disease activity, and treatment response in both RA and PsA.
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New Oral Option for axSpA: Filgotinib for Radiographic and Non-Radiographic Disease
The Janus kinase inhibitor (JAKi) class has been increasingly used in the management of axial spondyloarthritis (axSpA) over the past five years, offering effective oral alternatives to injectable biologics. But are all JAK inhibitors the same?
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Making Methotrexate More Effective
Dr. Jonathan Kay reports on abstract OP0206 and OP0207 presented at EULAR 2026 in London
https://t.co/HfzSPVbcBl https://t.co/n6FKX34j8p
Dr. John Cush @RheumNow( View Tweet )
Treat to Target Works in Elderly Onset RA
Dr. Jiha Lee reports on abstract POS1326 at EULAR 2026 in London
https://t.co/X4vhR9KofC https://t.co/TSquFmZJCP
Dr. John Cush @RheumNow( View Tweet )
Can you step down #belimumab
In well controlled #SLE without flaring?
N=22 on #BEL eligible of 152
Able to taper if
REM >6/12
No #steroids
Normal C3,C4
Neg #antiDNA
Remission maintained in pts who reduced dose
6/22 didn’t flare OFF Rx
✅nice
#POS1052 #EULAR2026
@RheumNow https://t.co/IEyfRtTGfT
Links:
Janet Pope @Janetbirdope( View Tweet )
Day 4 EULAR Report
The last day in London was exciting as both the Late-Breaking abstracts and new EULAR guidelines were presented. Guidelines presented addressed several significant unmet need areas including PMR, GCA, Takayasu’s arteritis, Vaccinations in Rheumatic patients, Imaging in spondyloarthritis and
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Remember
Babies of pts on chronic #immunosuppression with #SARDs
❎delay #vaccinations til 6/12
For safety & to mount sufficient response
#rotovirus #vaccine is Ok before 6 months or vaccine is ineffective
Pts w #SARDs need #COVID shots
@RheumNow #EULAR2026 #vaccine #recom https://t.co/WEzNajWlxY
Links:
Janet Pope @Janetbirdope( View Tweet )
What’s new with the 2026 update of reco for vax in AIIRD?
Vaccinate as soon as possible
Non-live vaccines are safe
Hold MTX for upto 2wks to inc vax yield
Strong reco for RZV
Catch-up vax for HPV in SLE
Rotavirus vax for newborns exposed in utero to TNFi
@RheumNow #EULAR2026 https://t.co/RZbyvAcYRI
Links:
sheila @RHEUMarampa( View Tweet )
Therapeutic Updates
Lupus Nephritis
Sponsored by RheumNow
View our six video perspectives on lupus nephritis, including Management of CKD in Lupus Nephritis.
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Recent Blogs
At first, it seemed similar to many other such sessions – a circle of folding chairs, a group of colleagues whose visages exuded understanding and acceptance – but this was special. I started the meeting…. “Hi, my name is Artie.”
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Podcasts
RA Topic Podcast compilation
PsA Topic Podcast compilation
EULAR 2026 Daily Podcast Day 4a
