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Rheumatoid Arthritis

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Rheumatoid Arthritis, Dementia and Cognitive Dysfunction

Dec 02, 2021

Rheumatoid arthritis (RA) has been linked to a higher risk of dementia and cognitive dysfunction, but interestingly this association has diminished in the last few decades with aggressive DMARD and targeted therapies..



This makes sense when you see that dementia in RA is associated

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Methotrexate and hepatic fibrosis: we must be doing something right

Dec 02, 2021

Methotrexate may be a rheumatologist’s best friend, but a key part of counselling any patient about its use has always been the risk of hepatotoxicity. Despite methotrexate’s near-ubiquitous use in rheumatology, and the consequent frequency of patient counselling about it, relatively little

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Prolonging the Controversy of Hydroxychloroquine

Nov 30, 2021

Since the start of the pandemic, hydroxychloroquine (HCQ) was forced into the limelight for the prevention/treatment of COVID-19. When it was found to be ineffective for COVID-19 and might cause potential harm, the drug came under closer scrutiny for its safety profile.

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Dr. Jack Cush interviews Professor Edward Keystone, MD (University of Toronto) on the origins and science behind the 60/40/20 benchmark and outcomes in rheumatoid arthritis.https://t.co/Ve6zOQPxZJ https://t.co/8RuL2CCsOQ
Dr. John Cush @RheumNow( View Tweet )
Nov 29, 2021
ICYMI:Food for Thought: "ITIS" Diet for Patients with Rheumatoid Arthritis: Dr. Akhil Sood ( @AkhilSoodMD) discusses abstract #1699 presented at the ACR21 annual meeting.https://t.co/bpQuzDGXCF https://t.co/9e2dYddsIx
Dr. John Cush @RheumNow( View Tweet )
Nov 29, 2021
ICYMI: Drs. Jeffrey Sparks, Greg McDermott and Vanessa Kronzer discuss work in the area of respiratory disease in RA, mucosal paradigm, RA-ILD, bronchiectasis, as well as their experience as virtual attendees at the #ACR21 annual meeting.https://t.co/5BrxeJBWM2 https://t.co/m8CqyJ1L7A
Dr. John Cush @RheumNow( View Tweet )
Nov 28, 2021
ICYMI: Does Control of Inflammation Lower Cancer Risk? https://t.co/OBMIdPki7O https://t.co/zV04iAOjAz
Dr. John Cush @RheumNow( View Tweet )
Nov 27, 2021
ICYMI: Multimorbidity, the presence of multiple overlapping chronic comorbid conditions, is increasingly common at first presentation of rheumatoid arthritis (RA), increasing as a person gets older and/or during disease progression. https://t.co/CL2xEyjKmd https://t.co/inoyahbkM9
Dr. John Cush @RheumNow( View Tweet )
Nov 27, 2021
Dr. Janet Pope and Dr. Jeffrey Sparks discuss the importance of lung and several lung-related abstracts presented at the ACR21 annual meeting. https://t.co/s5sl6tdKwP

Dr. John Cush @RheumNow( View Tweet )

Nov 26, 2021
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RheumNow Podcast - 60/40/20 Interview with Dr. Ed Keystone

Nov 26, 2021

Dr. Jack Cush interviews Professor Edward Keystone, MD (University of Toronto) on the origins and science behind the 60/40/20 benchmark and outcomes in rheumatoid arthritis.


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Better assessment and management of multimorbidity

Nov 26, 2021

Appropriate assessment and management of comorbidities and multimorbidity in patients with RA is vital for overall health and well-being of the patient, as well as to encourage treatment adherence, and address social, psychological and quality of life factors. 

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RA Treatment Conundrums: Dr. Janet Pope ( @Janetbirdope ) reviews abstracts #1252, #1442, #1438, #1444 and #1443 at the #ACR21 annual meeting.https://t.co/ftlRAq0CNK https://t.co/nnT37wG8l9
Dr. John Cush @RheumNow( View Tweet )
Nov 24, 2021
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Does Control of Inflammation Lower Cancer Risk?

Nov 23, 2021

Dr. Jonathan Kay's provocative video addresses whether the increased cancer risk associated with tofacitinib (Tofa) seen in the Pfizer Oral Surveillance (1133) study represents a real increased risk, an increased risk relative to a decreased risk with TNF inhibitors (TNFi) or an actual decreased

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Ultra Low Doses of Rituximab in RA: Dr. Eric Dein ( @ejdein1) and Nathan den Broeder \discuss abstract #1443 presented at the #ACR21 annual meeting.https://t.co/DpxkF5ffbt

Dr. John Cush @RheumNow( View Tweet )

Nov 23, 2021
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The Influence of Obesity on Choice of Biologic in Rheumatoid Arthritis

In rheumatoid arthritis we have a wide range of options available to us when we progress to a biologic treatment option. We have little to differentiate between these agents based on the clinical trials. We often make our choices based on minor hints from clinical features, comorbidities, or

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Improving Rheumatology Practice

Nov 22, 2021

How to best book patient appointments in rheumatology clinic? Should these be scheduled every 3 or 4 months regardless of patient status? Should they be scheduled by patient need or disease activity? 

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Long Term Steroid Use in RA - Matters of the Heart: Dr. Mrinalini Dey ( @DrMiniDey) discusses abstract #1428 presented at the #ACR21 annual meeting.https://t.co/E6RSlPAuRT https://t.co/QBhKD855aH
Dr. John Cush @RheumNow( View Tweet )
Nov 22, 2021
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RheumNow Podcast - Unwillingness to Change Therapy (11.19.21)

Nov 19, 2021

Surely you’ve seen this or been plagued by this patient, one that is not doing well, in need of a new regimen; you outline it, timeline it, define the side effects and send them off with a new prescription.. But you later find out they did not change, did not fill the prescription.  Why were

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Herpes Zoster and Rheumatoid Arthritis: Dr. Akhil Sood ( @AkhilSoodMD) reviews abstract #0981 presented at the #ACR21 annual meeting.https://t.co/M95XQOBWVf https://t.co/X9vaAEAias
Dr. John Cush @RheumNow( View Tweet )
Nov 19, 2021
GLORIA Study - Is Prednisone Harmful in Elder RA? The GLORIA study (ABST#1678) was a pragmatic, blinded placebo-controlled randomized trial where they assessed whether prednisolone (vs. placebo) use would alter clinical outcomes over 2 years.https://t.co/eKXjiDpHlc https://t.co/JtCgc1uZnE
Dr. John Cush @RheumNow( View Tweet )
Nov 19, 2021
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GLORIA Study - Is Prednisone Harmful in Elder RA?

Nov 17, 2021

The GLORIA study (ABST# 1678) was a pragmatic, blinded placebo-controlled randomized trial from Dr. Martin Boers and colleagues where they assessed whether prednisolone (vs. placebo) use would alter clinical outcomes over 2 years.



A total of 451 elder patients with established RA

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Potpourri of Biosimilar Trials: Dr. Jonathan Kay discusses a number of biosimilar trials presented at the #ACR21 annual meeting, including abstracts #0822, #0820, #0817 and #0823.https://t.co/aQXrKKZXhb https://t.co/4Bn7rvogHY
Dr. John Cush @RheumNow( View Tweet )
Nov 15, 2021
Lipidomic Differences in PsA and RA: Dr. Pedro Castillo ( @_Castillo_Pedro) discusses abstract #0946 presented at the #ACR21 annual meeting.https://t.co/M8O1OdvFAk https://t.co/4QMgXPhLzn
Dr. John Cush @RheumNow( View Tweet )
Nov 15, 2021
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RheumNow Podcast - ACR 2021 Rehash (the good stuff..)

Nov 12, 2021

The ACR 2021 meeting has concluded. Dr. Jack Cush recounts a few more great abstracts from this past week’s virtual meeting.

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Predicting RA, and Treatment of Subclinical Arthritis

Identifying patients that will develop RA in situations of seropositivity without overt clinical arthritis or identifying patients with undifferentiated oligo/polyarthritis that will develop RA remains a challenge in the field of rheumatology. 

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