Gout

2 T2T RCTs of 383 gout pts starting allopurinol - 31% had tophi. At 12 mos achieving target uric acid (<0.36mmol/L) was same in pts with and without tophi (70.3 vs 73.6), as was the %gout flares in month 11 (71.4% vs 79.7%; p=0.21). Allopurinol T2T success not influenced by https://t.co/zr7K8Y2Bqz

Dr. John Cush @RheumNow( View Tweet )

Jul 30, 2026

Gout patients have ↑ Cancer risk and ↓ risk of Parkinsons. For more gout content, follow our Gout: More than Flares campaign at https://t.co/lQoiFjubZJ, https://t.co/dJrXMFb9OS

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Gout Campaign - July 2026 | RheumNow

Dr. John Cush @RheumNow( View Tweet )

Jul 30, 2026

Treatment goals in gout: aim for remission!

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Nicola Dalbeth, MBChB, MD, FRACP, FRSNZ

Jul 30, 2026

Rheumatologists are used to the concept of disease remission as this is a treatment goal we use for many chronic rheumatic diseases in our clinical practice. Recently, G-CAN (the Gout and Crystal Arthritis Network), endorsed a

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"The best medicine I know for rheumatism is to thank the Lord that it ain't the gout." — Josh Billings (Henry Wheeler Shaw)

Dr. John Cush @RheumNow( View Tweet )

Jul 29, 2026

Evidence-Based Dietary Recommendations for Gout Gout, historically referred to as the “disease of kings,” was once associated with a lifestyle of excess. Today, it is more appropriate to refer to gout as a “disease of commoners,” as it is the most common inflammatory arthritis https://t.co/uIrSeOjxJZ

Dr. John Cush @RheumNow( View Tweet )

Jul 29, 2026

Tips for safe use of allopurinol

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Janet Pope, MD, MPH, FRCPC

Jul 29, 2026

These are tips and hopefully the patients are abstaining from moderate alcohol and are not tipsy! Here are 5 tips that may not be totally obvious.

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Persistence of education and monitoring is crucial to optimal gout management Optimal gout care is dependent on having a well-informed health care provider who recognizes and follows the ACR gout management recommendations. It is important that the misconceptions and myths held https://t.co/wDvgwUg2P1

Dr. John Cush @RheumNow( View Tweet )

Jul 28, 2026

Pragmatism in Gout: How therapeutic choices can have multiple benefits Drugs prescribed to calm flares or lower uric acid are designed with one primary goal in mind, yet many also produce meaningful effects beyond the joints. Some of those secondary effects are unwelcome; such https://t.co/QvXAwFM7LJ

Dr. John Cush @RheumNow( View Tweet )

Jul 28, 2026

Future therapies (in development) for gout - the goal is durable crystal depletion. Created by: Dr. Aravind Palraj @rheumat_aravind for RheumNow. https://t.co/rzP8usVZnT https://t.co/ZDuVWqT2TA

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Future Therapies for Gout | RheumNow

Dr. John Cush @RheumNow( View Tweet )

Jul 28, 2026

Uricase-Targeted Therapies in Gout

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Jack Cush, MD

Jul 28, 2026

In most mammals, uricase catalyzes the oxidation of uric acid to allantoin, a highly soluble compound easily excreted by the kidneys. But humans lack functional uricase, leaving xanthine oxidase inhibitors (allopurinol/febuxostat) as first-line urate-lowering therapy (ULT). Uricase-based

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Calcium Pyrophosphate Deposition Dz new terminology from 2026 G-CAN consensus. Preferred: - acute CPP crystal arthritis - Chronic CPP crystal arthritis - Chronic CPP crystal arthritis - OA w/ CPP - Chondrocalcinosis (xray) * Pseudogout is obsolete https://t.co/L95N2ObHr3 https://t.co/ST7RkJa8BR

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Expert Perspective: Treatment of Patients With Calcium Pyrophosphate Deposition…

Dr. John Cush @RheumNow( View Tweet )

Jul 27, 2026

RHEUMS! FINAL GOUT SURVEY ON NEW THERAPIES>> Which biologic is FDA-approved for gout? Answer here>> https://t.co/MWSnCZEDdR

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Treating Gout with New Therapies | RheumNow

Dr. John Cush @RheumNow( View Tweet )

Jul 27, 2026

The Hidden Cost of Gout For many people, gout is viewed as an episodic disease: a painful flare, a short course of treatment, and then life returns to normal. However, as rheumatologists, we know that recurrent attacks can lead to joint damage and tophi if left untreated. https://t.co/BfZFBZ8YrU

Dr. John Cush @RheumNow( View Tweet )

Jul 27, 2026

When Gout Flares, So Does the Cardiovascular System

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Edoardo Cipolletta, MD, PhD

Jul 27, 2026

We have spent decades teaching that a gout flare is a joint problem: a hot, swollen, painful joint that we treat with anti-inflammatory drugs and move on from (i.e., the treat to avoid symptoms strategy). The campaign title says it well — gout is more than flares. I would add

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UK primary care database (2000–21) gout study of new colchicine initiators (n 31,478) vs noninitiators (mean 60 yrs, BMI 30), follow-up of 4.5 yrs. Colchicine use had a signif. 12% lower risk of Joint Arthroplasty (HR 0.88); 23% lower TJA in knee/hip OA (HR 0.77) https://t.co/bT07lUYBB2

Dr. John Cush @RheumNow( View Tweet )

Jul 26, 2026

Pragmatism in Gout: How therapeutic choices can have multiple benefits William James famously wrote in Pragmatism, “There can be no difference anywhere that doesn’t make a difference elsewhere.” Gout treatment offers a striking medical example of that idea. https://t.co/DG29pro6XE

Dr. John Cush @RheumNow( View Tweet )

Jul 24, 2026

Black tart (Montmorency) cherries (or extract) have been shown to consistently reduce gout attacks. For more gout content, follow our Gout: More than Flares campaign at https://t.co/xnBVBN5IXZ, https://t.co/Ig6JLg3lcL

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Gout Campaign - July 2026 | RheumNow

Dr. John Cush @RheumNow( View Tweet )

Jul 24, 2026

Chikungunya Club Meeting (7.24.2026)

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Jack Cush, MD

Jul 24, 2026

Dr. Jack Cush reviews the news, journal reports from the past week on RheumNow.com.

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QD Clinic: Gout, Sepsis… or Both? Dr. Mrinalini Dey, London, discusses a complex case. https://t.co/UtncfZgZyL https://t.co/xVTA0LnPpN

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QD Clinic: Gout, Sepsis… or Both? | RheumNow

Dr. John Cush @RheumNow( View Tweet )

Jul 23, 2026

SGLT2 inhibitors lower serum urate AND reduce gout flares — and may close the mortality gap (CV mortality benefit) and offer renal protection. For more gout content, follow our Gout: More than Flares campaign at https://t.co/lQoiFjubZJ, https://t.co/QywxaTSSv6

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Gout Campaign - July 2026 | RheumNow

Dr. John Cush @RheumNow( View Tweet )

Jul 23, 2026

"Leeuwenhoek (invented the microscope) examined uric acid (C5H4N4O3) crystals from gout patients and found them to resemble needles. He expounded on his observations in an 11 July 1679 letter responding to an earlier query from Mr. Lambert van Velthuysen (1622–1685), a physician, https://t.co/mY2wqYlRda

Dr. John Cush @RheumNow( View Tweet )

Jul 23, 2026

QD Clinic: Gout, Sepsis… or Both? Dr. Mrinalini Dey, London, discusses a complex case. https://t.co/UtncfZgZyL https://t.co/81SyzpWbcl

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QD Clinic: Gout, Sepsis… or Both? | RheumNow

Dr. John Cush @RheumNow( View Tweet )

Jul 23, 2026

Dr. John Cush @RheumNow( View Tweet )

Jul 23, 2026

Evidence-Based Dietary Recommendations for Gout

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Chio Yokose, MD, MSC

Jul 23, 2026

Gout, historically referred to as the “disease of kings,” was once associated with a lifestyle of excess, including ready access to alcohol and rich meats once reserved for society’s highest ranks. Today, it is more appropriate to refer to gout as a “disease of commoners,” as it is

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QD Clinic: Gout: Is it the Journey or the Destination? Dr. Arthur Kavanaugh discusses a gout patient whose frequent flares improved after lifestyle changes, despite medication not being enough on its own. https://t.co/frf4O87L0I https://t.co/cjtiYY9Ayt

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QD Clinic: Gout: Is it the Journey or the Destination? | RheumNow

Dr. John Cush @RheumNow( View Tweet )

Jul 22, 2026

Therapeutic Updates

Systemic Burden of Gout

Jun 30, 2026

Watch our 'Systemic Burden of Gout' series as part of this month's Gout More than Flares campaign. Videos include: Gout Management in Patients with CKD, Gout and CVD, and Gout & Obesity.

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