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Gout/Crystal

RheumNow Podcast - Why we Love Rheumatology Fellows (8.7.20) Watch it here>> https://t.co/ftrycqoWRR or Listen to the podcast on iTunes or on SoundCloud>> https://t.co/gi5hO0HaIl

Dr. John Cush RheumNow ( View Tweet)

Aug 09, 2020
Full read clinical practice guideline on obesity management from the Canadian Medical Assn Journal. https://t.co/YdbjtnBcST

Dr. John Cush RheumNow ( View Tweet)

Aug 05, 2020
Virtual Video Joint Exam Pearl #5: Its easier to see gouty Tophi and rheumatoid nodules than nail changes of PsA or subtle rashes. For Rashes and oral lesions its BEST to have the patient take multiple pix with the cell phone and send them in by EMR or Email.

Dr. John Cush RheumNow ( View Tweet)

Aug 04, 2020

Uric Acid Targeting in Gout Management

Jul 31, 2020

A study from 2 gout clinics implementing different treatment strategies has shown that a treatment strategy that aims to strictly achieve low uric acid (UA) results in a higher a rate of targetd serum UA lowering and less gout flares.



Two gout clinics with 212 newly diagnosed gout

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RheumNow Podcast - Top 13 Rheumatology Centers (7-31-20)

Jul 31, 2020

Dr. Jack Cush reviews the news and TOP 13 list of Best Rheumatology Hospitals.

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Colchicine Benefits COVID-19 Patients

Jul 30, 2020

A proof-of-concept study published in Annals of Rheumatic Disease suggests that colchicine significantly improves COVID-19 outcomes.

Efficacy and safety must be determined in controlled clinical trials.he outbreak of COVID-19 posed the issue of urgently identifying treatment strategies.

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Methotrexate Improves Pegloticase Efficacy and Tolerability

Jul 29, 2020

The efficacy of intravenous pegloticase (PEG) therapy in gout can be limited by its toxicity, but when coadministered with weekly methotrexate, higher response rates and less toxicity was observed.



In published gout clinical trials, the PEG responder rate was 42%. Strategies to limit 

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Rising evidence of the link between hyperuricemia & hypertension, yet not enough that lowering uric acid (SUA) lowers HTN & its consequences.

Dr. John Cush RheumNow ( View Tweet)

Jul 29, 2020

The Burden of Gout

Jul 28, 2020

Danve and Neogi have an editorial in the current Arthritis & Rheumatology about the burden of gout that affects 41 million adults worldwide, according to the Global Burden of Disease Study 2017 (GBD 2017) also published in the same issue.

This makes gout twice as prevalent as rheumatoid

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Low Risk of COVID in Biologic Treated Rheum Patients

Jul 23, 2020

In an Annals of Rheumatic Disease report, Italian investigators performed consecutive testing for SARS-CoV-2 (IgM and IgG) between 25 March to 25 May 2020 and compared test results between rheumatic disease (RMD) patients and the general population. 



Their study included 295

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RheumNow Podcast is Up! Listen to Fauci! Watch it here>> https://t.co/dHq3fP85Ip or Listen to the Podcast>> https://t.co/LdHO7fKUCp

Dr. John Cush RheumNow ( View Tweet)

Jul 17, 2020

RheumNow Podcast – LTF – Listen to Fauci (7.17.20)

Jul 17, 2020

Dr. Jack Cush reviews the news, tweets and journal articles from the past week on RheumNow. Let's dig into this week's 14 highlights.

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The preliminary #ACR20 schedule is here! Along with all your favorite plenary and networking sessions, the program will feature #Rheumatologist Dr. Anthony Fauci giving us a live update on #COVID19.

Victoria Shanmugam VickiShanmugam ( View Tweet)

Jul 16, 2020
EMR analysis of 453 gout pts D/C from ED or hospital , shows that 28.3% received opioids at discharge (~80% new pts).

Dr. John Cush RheumNow ( View Tweet)

Jul 14, 2020
Open label, uncontrolled study shows that background use of azathioprine (2mg/kg) in Pegloticase treated refractory… https://t.co/uXQR8JE1he

Dr. John Cush RheumNow ( View Tweet)

Jul 10, 2020
Rheumatology Round-Up from #EULAR2020 w/ Drs. Kavanaugh & Cush.

Dr. John Cush RheumNow ( View Tweet)

Jul 07, 2020

RheumNow Podcast – Gout Guidelines (7.3.20)

Jul 03, 2020

Dr Jack Cush reviews the journal reports and news from RheumNow this past week. Highlights include:

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2020 ACR Gout Management Guideline

Jul 03, 2020

In May, the American College of Rheumatology (ACR) released the"2020 Guideline for the Management of Gout"reflecting new clinical evidence since the last guideline published in 2012.



The guideline puts forth 42 recommendations, including 16 strong recommendations, based in 52 PICO

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Coexistent Gout and Rheumatoid Arthritis

Jul 02, 2020

While it is often said there is a negative association between gout and rheumatoid arthritis (RA), cases of coexistent disorders are uncommonly seen. A recent VA study describes 121 patients whith both RA and gout.

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High uric acid is associated with a higher risk of kidney cancer, especially in women; Data from a UK biobank of 444 462 without cancer w/ 6.5 yrs F/U. Highest Urate quartile had increased risk of renal cancer (HR 1.45, 95%CI 1.08 to 1.93), only in women.

Dr. John Cush RheumNow ( View Tweet)

Jun 26, 2020
The RheumNow Podcast is Up! Lupus Mortality Declines, But… Review of SUA and cancer; IL-12/23 and SLE; TCZ and Behcets, Pregnancy SI MRI, VTE w/ Jaks; COVID; Colchicine.

Dr. John Cush RheumNow ( View Tweet)

Jun 26, 2020

RheumNow Podcast – Lupus Mortality Declines, But… (6.26.20)

Jun 26, 2020

Dr Jack Cush reviews the news and journal articles from the past week on RheumNow.com

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Methotrexate May Enhance Pegloticase Response in Gout

Jun 15, 2020

For patients with gout exacerbations while on pegloticase (Krystexxa), adding methotrexate may help reduce uric acid levels, researchers suggested at the European League Against Rheumatism (EULAR) virtual meeting.

In a small open-label study of 14 patients experiencing acute gout attacks, use

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#EULAR2020 #op0015 relationship btw sUA &mortality in the US: increased mortality in M w/ low sUA but not F. could be attributed to uricosuric effect of uncontrolled hyperglycemia ( high incidence of DM)? Lower Alzheimer’s mortality in M&F w/high sUA.
Olga Petryna DrPetryna ( View Tweet)
Jun 07, 2020
#eular2020 #op0205 phase 1 trial of novel URAT1 inhibitor D-0120 in healthy adults: safe up to 20 mg/d after 7 days. Significant reduction of sUA peaks at 4-8h & lasts up to 24h @RheumNow

Olga Petryna DrPetryna ( View Tweet)

Jun 07, 2020
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