Rheumatology Pay Up (9.25.2026)
Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.
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It’s almost time. 🔥
Registration for RheumNow Live 2027 opens OCTOBER 1.
Two days of practical, engaging rheumatology education designed to challenge how you think and influence how you practice.
📅 Jan 30–31, 2027
📍 Dallas + Online https://t.co/Ju0zzYX8Tl
Dr. John Cush @RheumNow( View Tweet )
Obesity and Gout: An Old Relationship with New Thoughts
https://t.co/T71u9Ta4NS https://t.co/B7vUVqIBQE
Dr. John Cush @RheumNow( View Tweet )
FORWARD is a Phase 4, OL trial in 51 refractory uncontrolled gout pts Rx w/ MTX plus higher doses pegloticase (16 or 30mg) IV q4wk. At 24-wk Responses similar 68% or 73%. ~31% of responders later had SUA >6. Confusing anti-Drug Ab results in this trial?? https://t.co/udjE7sXDm5 https://t.co/F8VGDAyJzb
Dr. John Cush @RheumNow( View Tweet )
Discussing Weight Loss: 3 Minute Script
Dr. Jack Cush's 3 Minute Script as discussed in his Introducing Weight Loss video.
https://t.co/JRWAPc5if5 https://t.co/jI65VzTIfs
Dr. John Cush @RheumNow( View Tweet )
Obesity and Rheumatic Disease
Presented as part of RheumNow's "The Obesity Imperative" campaign.
https://t.co/d2fl4EJX8Q https://t.co/AZGfKRvZrx
Dr. John Cush @RheumNow( View Tweet )
Early RA Referral Clinics Work (9.18.2026)
Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com
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Obesity and Gout: An Old Relationship with New Thoughts
Current recommendations are that obesity management is an integral component of gout treatment and that, in parallel, gout awareness is an important component in the treatment of the metabolic syndrome.
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Metanalysis 11 studies & 104277 gout & hyperuricemic pts shows erectile dysfunction is signif. increased (RR1.37; 1.14-1.65) related to lower testosterone & estradiol. Other factors: obesity, age, DM, CVD. https://t.co/1ufih2E3UN https://t.co/NgQuHt4vR1
Dr. John Cush @RheumNow( View Tweet )
True or False: In a Korean National Health Insurance study, gout patients on allopurinol had a significantly higher risk of fractures, with the highest risk seen in those with low adherence.
Did you get it right?
Take this week's RheumIQ and see: https://t.co/UaXqHKWizt. https://t.co/7nILMVUeGw
Dr. John Cush @RheumNow( View Tweet )
Treating Obesity is Disease-Modifying (9.4.2026)
Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com. New drugs approved, new drugs halted and some drugs out of control. Ready to test your knowlege? Take this week's quiz!
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Korean National Health Insurance claims study of 4,107 newly Dx gout on allopurinol x 24 mos (vs non-gout controls). Gout significantly higher risk of fractures (aHR 5.52_; 95% CI 4.19–7.26), highest in those with low-adherence to allopurinol (aHR 5.91). Consistent trends seen https://t.co/cTO4lGtYAy
Dr. John Cush @RheumNow( View Tweet )
Rheums! Do you have a Rheumatology question or case for Dr. Cush? Record it here, and we may feature it on an upcoming podcast. Tell us your name and where you practice rheumatology.
https://t.co/LZ59KW8HdA https://t.co/DwHdvpTYax
Dr. John Cush @RheumNow( View Tweet )
True or False: Compared to adult systemic sclerosis, juvenile systemic sclerosis is more commonly associated with diffuse cutaneous disease and renal crisis.
Test your knowledge in this week's RheumIQ at https://t.co/TBlB4pmnKa. https://t.co/q4wlnCQsny
Dr. John Cush @RheumNow( View Tweet )
QD Clinic: A Watched Tophus Never Resolves
Dr. Jack Cush discusses his plan to medically manage multiple large volume tophi and a patient who has recently started urate lowering therapy with febuxostat.
https://t.co/swfyYEeW0s https://t.co/wyLlcHR4Td
Dr. John Cush @RheumNow( View Tweet )
Systemic Burden of Gout
https://t.co/OUgXMtH1bn https://t.co/zK7vRCevTY
Dr. John Cush @RheumNow( View Tweet )
New, Advanced Therapies in Gout
https://t.co/7i6936H7ZS https://t.co/8oOzqVKLGF
Dr. John Cush @RheumNow( View Tweet )
Survey: Upgrading & Maximizing the Classics (Urate Lowering Therapies, etc)
https://t.co/w6uzIlaeG7 https://t.co/HW09DVrMed
Dr. John Cush @RheumNow( View Tweet )
Congratulations to Dr. Edoardo Cipolletta (U Nottingham) - winner of Gout, Urate, and Crystal Deposition Disease Best PhD Thesis Award. Read his insightful interview on his reasearch on #gout. https://t.co/5i3hEV6PJX https://t.co/XV5trvEonW
Dr. John Cush @RheumNow( View Tweet )
Systemic Burden of Gout
https://t.co/OUgXMtH1bn https://t.co/1AtaFwZ2SR
Dr. John Cush @RheumNow( View Tweet )
Four Decades of Gout Management
During this month-long campaign on Gout, we have documented many significant changes in our approach to gout, as well as many unmet needs and deficiencies that merit our continued primary attention.
https://t.co/ddzj3RktDD https://t.co/x7o0HfWqHa
Dr. John Cush @RheumNow( View Tweet )
New, Advanced Therapies in Gout
New, Advanced Therapies in Gout explores the rapidly evolving therapeutic landscape beyond conventional urate-lowering therapy.
https://t.co/0uNK0nOEp6 https://t.co/YD7tQu2QrT
Dr. John Cush @RheumNow( View Tweet )
QD Clinic: Addressing Severe Gout Flares
Dr. Eric Dein, Summit, NJ, discusses a difficult-to-treat case of gout.
https://t.co/tochY0BUBj https://t.co/9hQ13cDY9s
Dr. John Cush @RheumNow( View Tweet )
A Tribute to Daniel L. Kastner, MD, PhD (1951–2026)
The rheumatology, genetics and NIH communities mourn for Dr. Daniel L. Kastner, who died on July 28, 2026, in Bethesda, Maryland, at age 74. The following are declarations, tributes, and memories dedicated to this mensch of a man, titan of science, memorable mentor and humble physician.
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Gout & Metabolic Syndrome
Dr. John Fitzgerald, Los Angeles, hates the expression "It's only Gout."
https://t.co/0JipL3kgcM https://t.co/jszxYAfZwa
Dr. John Cush @RheumNow( View Tweet )
Therapeutic Updates
Watch our 'Systemic Burden of Gout' series as part of this month's Gout More than Flares campaign. Videos include: Gout Management in Patients with CKD, Gout and CVD, and Gout & Obesity.
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Recent Blogs
A few years ago, when I would see a patient with rheumatic disease and increased BMI, I would often document it as obesity as a comorbidity, recommend weight loss and exercise, and then move on. My approach has changed.
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Dr. Jack Cush reviews Gout in this continuing series for Advanced Practice Rheum. Review the companion slide deck here.
Dr. Cush provides a systematic approach to evaluating musculoskeletal and rheumatic complaints in clinical practice.
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Podcasts
TU: Systemic Burden of Gout Part 2 (24 plus)
Gout Lessons from the Clinic Part 3
Systemic Burden of Gout Part 1
