Gout

Korean National Health Insurance claims study of 4,107 newly Dx gout on allopurinol x 24 mos (vs non-gout controls). Gout significantly higher risk of fractures (aHR 5.52_; 95% CI 4.19–7.26), highest in those with low-adherence to allopurinol (aHR 5.91). Consistent trends seen https://t.co/cTO4lGtYAy
Dr. John Cush @RheumNow( View Tweet )
Rheums! Do you have a Rheumatology question or case for Dr. Cush? Record it here, and we may feature it on an upcoming podcast. Tell us your name and where you practice rheumatology. https://t.co/LZ59KW8HdA https://t.co/DwHdvpTYax

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True or False: Compared to adult systemic sclerosis, juvenile systemic sclerosis is more commonly associated with diffuse cutaneous disease and renal crisis. Test your knowledge in this week's RheumIQ at https://t.co/TBlB4pmnKa. https://t.co/q4wlnCQsny

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Dr. John Cush @RheumNow( View Tweet )
QD Clinic: A Watched Tophus Never Resolves Dr. Jack Cush discusses his plan to medically manage multiple large volume tophi and a patient who has recently started urate lowering therapy with febuxostat. https://t.co/swfyYEeW0s https://t.co/wyLlcHR4Td

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Dr. John Cush @RheumNow( View Tweet )
Systemic Burden of Gout https://t.co/OUgXMtH1bn https://t.co/zK7vRCevTY

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Dr. John Cush @RheumNow( View Tweet )
New, Advanced Therapies in Gout https://t.co/7i6936H7ZS https://t.co/8oOzqVKLGF

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Dr. John Cush @RheumNow( View Tweet )
Survey: Upgrading & Maximizing the Classics (Urate Lowering Therapies, etc) https://t.co/w6uzIlaeG7 https://t.co/HW09DVrMed

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Dr. John Cush @RheumNow( View Tweet )
Congratulations to Dr. Edoardo Cipolletta (U Nottingham) - winner of Gout, Urate, and Crystal Deposition Disease Best PhD Thesis Award. Read his insightful interview on his reasearch on #gout. https://t.co/5i3hEV6PJX https://t.co/XV5trvEonW

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Dr. John Cush @RheumNow( View Tweet )
Systemic Burden of Gout https://t.co/OUgXMtH1bn https://t.co/1AtaFwZ2SR

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Dr. John Cush @RheumNow( View Tweet )
Four Decades of Gout Management During this month-long campaign on Gout, we have documented many significant changes in our approach to gout, as well as many unmet needs and deficiencies that merit our continued primary attention. https://t.co/ddzj3RktDD https://t.co/x7o0HfWqHa

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Dr. John Cush @RheumNow( View Tweet )
New, Advanced Therapies in Gout New, Advanced Therapies in Gout explores the rapidly evolving therapeutic landscape beyond conventional urate-lowering therapy. https://t.co/0uNK0nOEp6 https://t.co/YD7tQu2QrT

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Dr. John Cush @RheumNow( View Tweet )
QD Clinic: Addressing Severe Gout Flares Dr. Eric Dein, Summit, NJ, discusses a difficult-to-treat case of gout. https://t.co/tochY0BUBj https://t.co/9hQ13cDY9s

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Dr. John Cush @RheumNow( View Tweet )
Dan.Kastner

A Tribute to Daniel L. Kastner, MD, PhD (1951–2026)

Jack Cush, MD

The rheumatology, genetics and NIH communities mourn for Dr. Daniel L. Kastner, who died on July 28, 2026, in Bethesda, Maryland, at age 74. The following are declarations, tributes, and memories dedicated to this mensch of a man, titan of science, memorable mentor and humble physician.

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Gout & Metabolic Syndrome Dr. John Fitzgerald, Los Angeles, hates the expression "It's only Gout." https://t.co/0JipL3kgcM https://t.co/jszxYAfZwa

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Dr. John Cush @RheumNow( View Tweet )
Treatment goals in gout: aim for remission! Rheumatologists are used to the concept of disease remission as this is a treatment goal we use for many chronic rheumatic diseases in our clinical practice. Recently, G-CAN (the Gout and Crystal Arthritis Network), endorsed a https://t.co/PP2NBqvo7E
Dr. John Cush @RheumNow( View Tweet )
Tips for safe use of allopurinol https://t.co/Yn1u1bEj4F https://t.co/lMWPI9OsVe

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Dr. John Cush @RheumNow( View Tweet )
Gout: Diagnosis The diagnosis of gout - labs, imaging and polarized microscopy, created by @MithuRheum for RheumNow. https://t.co/s8gkANFJSB https://t.co/pkUeFLG5if

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Dr. John Cush @RheumNow( View Tweet )
Future therapies (in development) for gout - the goal is durable crystal depletion. Created by: Dr. Aravind Palraj @rheumat_aravind for RheumNow. https://t.co/yeCSAnHiY2 https://t.co/nH8f2Y3hNP

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Dr. John Cush @RheumNow( View Tweet )
Calcium Pyrophosphate Deposition Dz new terminology from 2026 G-CAN consensus. Preferred: - acute CPP crystal arthritis - Chronic CPP crystal arthritis - Chronic CPP crystal arthritis - OA w/ CPP - Chondrocalcinosis (xray) * Pseudogout is obsolete https://t.co/bsztXz9UDs https://t.co/GOey5YmKif

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Dr. John Cush @RheumNow( View Tweet )
New GoutStop cards - print and give to your gout patients! https://t.co/Bh0IuM5tzu https://t.co/j5rQJStSnu

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Dr. John Cush @RheumNow( View Tweet )
RheumNow Podcast square

Methotrexate Safety Tips (7.31.2026)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal articles from this past week on RheumNow.com.

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Uricase-Targeted Therapies in Gout https://t.co/RB6Yj4oY9a https://t.co/NrWq6Y93Hg

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Dr. John Cush @RheumNow( View Tweet )
gout,podagra,MTP

Four Decades of Gout Management

Jack Cush, MD

During this month-long campaign on Gout, we have documented many significant changes in our approach to gout, as well as many unmet needs and deficiencies that merit our continued, primary attention.  We are all familiar with the famous 1905 quote, “Those who cannot remember the past

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When Gout Flares, So Does the Cardiovascular System We have spent decades teaching that a gout flare is a joint problem: a hot, swollen, painful joint that we treat with anti-inflammatory drugs and move on from (i.e., the treat to avoid symptoms strategy). The campaign title https://t.co/HCUQVaor4f
Dr. John Cush @RheumNow( View Tweet )
2 T2T RCTs of 383 gout pts starting allopurinol - 31% had tophi. At 12 mos achieving target uric acid (<0.36mmol/L) was same in pts with and without tophi (70.3 vs 73.6), as was the %gout flares in month 11 (71.4% vs 79.7%; p=0.21). Allopurinol T2T success not influenced by https://t.co/zr7K8Y2Bqz
Dr. John Cush @RheumNow( View Tweet )

Therapeutic Updates

Systemic Burden of Gout

Dr. Mark Fisher
Watch our 'Systemic Burden of Gout' series as part of this month's Gout More than Flares campaign. Videos include: Gout Management in Patients with CKD, Gout and CVD, and Gout & Obesity.
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Recent Blogs

Advanced Practice Rheum

Gout

Jack Cush, MD
APR video gout cover

Dr. Jack Cush reviews Gout in this continuing series for Advanced Practice Rheum. Review the companion slide deck here.

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Advanced Practice Rheum

Evaluation of Rheumatic Complaints

Jack Cush, MD
Eval of Rheum Complaints Cover Image
Dr. Cush provides a systematic approach to evaluating musculoskeletal and rheumatic complaints in clinical practice.
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A Brief History of Rheumatoid Arthritis Mimics

Robert Schoen, MD, MBA
books history
Imagine that 100 years from now, your great granddaughter, an eminent rheumatologist, reviews the history of rheumatoid arthritis mimics.
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Podcasts

  • TU: Systemic Burden of Gout Part 2 (24 plus)
  • Gout Lessons from the Clinic Part 3
  • Systemic Burden of Gout Part 1
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