Tweets
Might stem cells actually work in knee OA??
Possibly, only the right combo 🇰🇷
OSCA: OS (allo mesenchymal stem cells) + CAM (cartilage acellular matrix)
anti-inflamm, structural, pain
ph2a
impressive signal over placebo
& maybe tissue repair, benefit out to 5y?
#ACR26 @RheumNow https://t.co/PU3MUqxH7Q
David Liew @drdavidliew ( View Tweet )
14 hours 29 minutes ago
It's like HCQ on steroids
(metaphorical not literal, & anabolic not glucocorticoid)
TLR7/8 targeting in SLE (IFN-I, GC resistance, organ damage)
ph2: massive signal in primary, secondaries all hit, IFN-I down from w2, safety good
what a time for lupus
ABSTLB23 #ACR26 @RheumNow https://t.co/mhntxC4aT4
David Liew @drdavidliew ( View Tweet )
14 hours 29 minutes ago
Is 60-40-20 broken?
RA trial rule of thumb:
roughly 60%-40%-20% for ACR20-50-70
girocitinib (JAK1/Tyk2) vs tofacitinib
ACR20: 91% vs 75%
ACR50: 73% vs 49%
ACR70: 44% vs 25%
there will be debate (all in China, tofa exposure)
but what a meeting for H2H
ABSTLB21 #ACR26 @RheumNow https://t.co/SmOCzqqxFg
David Liew @drdavidliew ( View Tweet )
14 hours 29 minutes ago
Final #ACR2026 post (maybe? 😄)! Huge shoutout to @RheumNow and the incredible team for their phenomenal work in rheumatology education! Can’t believe it took me this long to collaborate with them, but I have a feeling this is the beginning of a long-term relationship! 🙌
anita @docdhanrajani ( View Tweet )
14 hours 29 minutes ago
@RheumNow The narrative medicine interactive session at #ACR2026 was well attended and had a lot of interesting exchange of thoughts and ideas. Holistic care of patients, attention to caregiver burnout and ensuring provider well being is the need of the hour in rheumatology.
anita @docdhanrajani ( View Tweet )
14 hours 29 minutes ago
@RheumNow 🎉 Celebrated 50 years of #PediatricRheumatology at #ACR2026! Meet the Masters: 3 pioneers reflected on the evolution of our field—from early genetics and DMARDs to biologics—and envisioned the future of precision medicine, novel therapies, and mentorship. What a treat
anita @docdhanrajani ( View Tweet )
14 hours 30 minutes ago
@RheumNow #1! 🌍 Global pediatric rheumatology workforce challenges! A survey across 32 countries found 40% lacked in-country training programs. Variable accreditation, limited funding & poor specialty awareness remain key barriers. Abstract 1483. #ACR2026
anita @docdhanrajani ( View Tweet )
14 hours 30 minutes ago
Is it the treatment or the disease?
-Multiple meds can cause SCLE: more widespread, EM,Bullous features.
-Dupilumab can cause enthesitis: if severe needs dc of medication
-Anti-CD 20 may cause IBD (Crohn’s-Like)
Great lecture from @md_chawla on Drug induced syndromes
#ACR26 https://t.co/EEQL7QNtWC
Links:
Adela Castro @AdelaCastro222 ( View Tweet )
14 hours 30 minutes ago
ACR26 summary, AI and documentation: errors on all five AI platforms tested against guidelines, and cDAPSA documented in 4.9% of PsA records @rheumnow #ACR26 Abstract#0869 Abstract#1348
Antoni Chan MD (Prof) @synovialjoints ( View Tweet )
14 hours 30 minutes ago
ACR26 summary, gut joint axis: replenishing TRBV9 CD8 T cells, a dual targeting antibody, calprotectin for gut inflammation, and outcomes of joint gastroenterology and rheumatology meetings. @rheumnow #ACR26 Abstract#1027 Abstract#2941 Abstract#1336 Abstract#2287
Antoni Chan MD (Prof) @synovialjoints ( View Tweet )
14 hours 30 minutes ago
@RheumNow #2. Abstract 1876. A consensus-driven core outcome set for healthcare transition in adolescents and young adults with JIA identifies 10 outcomes spanning the Quadruple Aim framework: Population health, experience of care, cost of care, provider experience. #ACR2026
anita @docdhanrajani ( View Tweet )
14 hours 30 minutes ago
#ACR26 #2965: AI-generated answers to common pt Qs were rated similarly to rheumatologist-written answers. The highest-value approach, was AI plus rheumatologist review, which improved utility, readability, and completeness. The future may be hybrid, not human versus AI.@RheumNow
Bella Mehta @bella_mehta ( View Tweet )
14 hours 30 minutes ago
@RheumNow #3. Abstract 0041. Can CAR-T therapy truly “reset” the immune system in lupus? Promising findings show that both patient and donor-derived CAR-T suppress key inflammatory gene signatures in SLE, suggesting a molecular immune reset beyond clinical remission. #ACR26
anita @docdhanrajani ( View Tweet )
14 hours 30 minutes ago
ACR26 summary, diagnosis and classification: lower sensitivity of the 2025 ASAS SPARTAN criteria in early axSpA, and a 28 month reduction in diagnostic delay with an integrated referral pathway. @rheumnow #ACR26 Abstract#2347 Abstract#2540
Antoni Chan MD (Prof) @synovialjoints ( View Tweet )
14 hours 30 minutes ago
Reflection on sequencing: antibody status and patient factors predicted outcome more than mechanism, TNFi cycling was the most common switch in the last 2 decades, and Leeds data suggest some treatment failure may be iatrogenic. @rheumnow #ACR26 Abstract#2284 Abstract#1324
Antoni Chan MD (Prof) @synovialjoints ( View Tweet )
14 hours 30 minutes ago