Tweets
Beyond HLA-B27: Anti-14-3-3eta Autoantibodies as a Candidate Marker in axSpA
14-3-3 proteins are a conserved family of seven isoforms with diverse cellular functions, found predominantly intracellularly. The 14-3-3eta isoform has been studied as a proinflammatory mediator in RA https://t.co/yC4bhtnTCD
Dr. John Cush @RheumNow ( View Tweet )
10 minutes 2 seconds ago
PMR: Spare The Steroids Please
Steroids remain both the cornerstone and the Achilles' heel of PMR management. We have aspirations of briskly tapering our patients once they have had their honeymoon phase with prednisone. But when Ms. Jones calls you with a reported second PMR https://t.co/dbrdVZRuoN
Dr. John Cush @RheumNow ( View Tweet )
1 hour 10 minutes ago
All RA-ILD deserves a trial of immunomodulation
The optimum treatment approach in RA-ILD remains an area mired in controversy. This is evident from the contrasting views taken by the 2 recent expert guidelines from ACR and EULAR, which advocate for very different treatment https://t.co/vxr8NDruGI
Dr. John Cush @RheumNow ( View Tweet )
2 hours 10 minutes ago
IgG4-RD in 3 Talks: Shorter Steroids, Earlier B-Cell Therapy
IgG4-related disease now has two phase 3 trials and its first dedicated treatment guidelines. Glucocorticoids remain the weak point.
https://t.co/pWu1eoiMVG https://t.co/yXXk0R4Rbs
Dr. John Cush @RheumNow ( View Tweet )
3 hours ago
New Treatment for Fibromyalgia? Will It Help or Harm?
For years, the pharmacologic treatment landscape for fibromyalgia has remained relatively unchanged, with limited therapeutic options despite a substantial disease burden. This condition is characterized by chronic https://t.co/nn9wu7xibY
Dr. John Cush @RheumNow ( View Tweet )
3 hours 40 minutes ago
Biologic Dosing and Obesity
A 46-year-old with pSa and a BMI of 38 still has active disease on adalimumab (Humira) 40 mg every other week. What do you do? Stephen Balevic, MD, PhD, discusses this question in "Prescribing the Right Dose: How Obesity Alters Drug https://t.co/0SGQGs32U2
Dr. John Cush @RheumNow ( View Tweet )
5 hours 10 minutes ago
What's next for a patient with PsA and GI symptoms who failed a csDMARD?
🔊 Listen to Dr. Saakshi Khattri discuss this case and the data that shaped her treatment decision with Lindsay Tom, PA-C.
Sponsored by AbbVie Medical Affairs + Health Impact.
https://t.co/MOBlwXCFuu https://t.co/QehwMdZyI5
Dr. John Cush @RheumNow ( View Tweet )
5 hours 40 minutes ago
One Diagnosis, Different Diseases: Is TLR7/8 Inhibition the Future of Lupus Treatment?
We call it systemic lupus erythematosus (SLE), but are we really treating one disease? Increasingly, I wonder whether grouping biologically distinct patients under one diagnosis is limiting https://t.co/30MGwIRUgO
Dr. John Cush @RheumNow ( View Tweet )
20 hours 10 minutes ago
Cardiovascular Risk in Rheumatoid Arthritis
What is the link between cardiovascular risk and dementia?
In abstract 1454, Michelle Allen and colleagues at Mayo Clinic studied 2,483 adults with incident RA diagnosed between 1980 and 2019. Patients were followed for Alzheimer’s https://t.co/JaITrlZXIt
Dr. John Cush @RheumNow ( View Tweet )
20 hours 40 minutes ago
🔎Long-term malignancy risk remains an important consideration in RA treatment
See the SELECT trial program 5-year malignancy risk data for a JAKi and TNFi in RA, including in high CV-risk patients: https://t.co/1PBrCKLRan
Sponsored by AbbVie Medical Affairs + Health Impact. https://t.co/hxzGpxWW0s
Dr. John Cush @RheumNow ( View Tweet )
22 hours 10 minutes ago
ACR 2026 – Day 2 Report
https://t.co/H5aJMSwHwk https://t.co/gzGSaA9czB
Dr. John Cush @RheumNow ( View Tweet )
22 hours 55 minutes ago
Are GLP-1s Doing More Than Shrinking Waistlines in PsA?
In abstract #0373, Pankti Mehta and colleagues examined patients from a longitudinal PsA cohort who initiated GLP-1 receptor agonist or dual GIP/GLP-1 therapy and compared them with matched controls. Baseline body mass https://t.co/FGCszLnS4N
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
📢 "We can't have a one-size-fits-all approach" – Dr. Saakshi Khattri
Hear Dr. Khattri and Lindsay Tom, PA-C, explore the latest IL-23i and JAKi data and how it impacts their PsA treatment decisions. Sponsored by AbbVie Medical Affairs + Health Impact.
https://t.co/MOBlwXCFuu https://t.co/2pHRO1SQCS
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
Scary IPAF
IPAF describes patients who have ILD plus clinical, serologic, or morphologic features of autoimmunity but who do not meet criteria for a defined connective tissue disease. The 2015 ERS/ATS criteria proposed IPAF as a research classification, not a distinct disease, https://t.co/v3ir4IHia7
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
Beyond Joint Inflammation: Does Early RA Control Prevent Chronic Pain and Fatigue?
Could the therapeutic window of opportunity in rheumatoid arthritis extend beyond preventing structural damage to preventing chronic pain, fatigue, and neuroimmune complications?
This is the https://t.co/WVSjwIHOAM
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
