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FDA - a 120Year History Protecting Americans. Nice overview. - Began 1906 (as Bureau of Chemistry) w/ Pure Food & Drugs Act - 1930 changed to Food and Drug Administration - 1938 Food, Drug, and Cosmetics Act - 1960s denied thalidomide approval https://t.co/3Ey98M9sxw My https://t.co/JS36EfJ19k
Dr. John Cush @RheumNow ( View Tweet )
1 hour 52 minutes ago
DMARD Efficacy in RA-ILD A network meta-analysis in the Journal of Autoimmunity reviews the pharmacologic options for rheumatoid arthritis–associated interstitial lung disease (RA-ILD). RA-ILD guidelines were recently presented by ERS/EULAR, but these were mainly conditional,

Dr. John Cush @RheumNow ( View Tweet )

3 hours 52 minutes ago
New research shows synovial lining enriched in macrophages expressing SPP1 (encoding osteopontin) in proximity to fibroblasts and fibrin deposits. SPP1+ macrophages degrade fibrin & promote fibroblast proliferation that deposit collagen & does the damage, joint remodeling. A new https://t.co/yFxwAYFPPb
Dr. John Cush @RheumNow ( View Tweet )
5 hours 51 minutes ago
"People wish their enemies dead—but I do not; I say give them the gout, give them the stone!" — Mary Wortley Montagu

Dr. John Cush @RheumNow ( View Tweet )

7 hours 51 minutes ago
Uric Acid: Is Lower Better? There is good evidence that a serum urate less than 6 mg/dL is required to meaningfully reduce urate crystal and gout flare burden, but is even lower better and are there any tradeoffs? https://t.co/W5FsDC5FG0 https://t.co/7mRgkg00uV
Dr. John Cush @RheumNow ( View Tweet )
9 hours 52 minutes ago
Updated Algorithm for the Management of Restless Legs Syndrome Diagnose: chronic vs intermittent RLS (no need for polysomnography) Test Iron levels (& Rx if) Consider: remove exacerbators; walking/massage/heat; carbidopa/ levodopa; pramipexole or ropinirole; low potency opioids; https://t.co/XdzIipw1X8
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
Learn more about the fundamentals of CAR T-cell therapy and its investigational use in autoimmune disease. Sponsored by Bristol Myers Squibb. https://t.co/VvTOYY3tvz #CARTCellTherapy https://t.co/kaTom2dEnZ
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
True or False: EULAR recommends glucocorticoids alone, without additional agents, for remission induction in life-threatening ANCA-associated vasculitis. Did you get it right? Take this week's RheumIQ quiz at https://t.co/TBlB4pmnKa. https://t.co/4IsId6lJ4Y
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
In a claims analysis, 28.1% of patients with PsA had ≥1 predictor of IBD development at PsA diagnosis. 📊Which predictors had the highest association with future IBD? Click to learn more: https://t.co/x2pM0T9LWg Sponsored by AbbVie Medical Affairs + Health Impact. https://t.co/uDxtvPAgOK
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
True or False: There is an available antidote for colchicine overdose. Check your answer in this week's RheumIQ at https://t.co/TBlB4pmnKa. https://t.co/RgJ4xEAuZA
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
The mortality gap in gout has not improved in 20 years – CV disease is the leading cause of death (2-fold increase). For more gout content, follow our Gout: More than Flares campaign at https://t.co/xnBVBN5IXZ, https://t.co/c12GmMaatt
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
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