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Fibrosis-4 (FIB-4) Index for Liver Fibrosis is calculated from age, AST, ALT, Plts. Study of 174 RA, PsA, PsO pts on MTX find 11% w/ fibrosis (by elastography). FIB-4 AUC for fibrosis =0.68 (weak). Fibrosis was signif assoc w/ FIB-4 >1.62, DM, obesity, advanced steatosis https://t.co/GYrhs2U1s3
Dr. John Cush @RheumNow ( View Tweet )
21 minutes 32 seconds ago
Learn more about the fundamentals of CAR T-cell therapy and its investigational use in autoimmune disease. Sponsored by Bristol Myers Squibb. https://t.co/eZQoVpZpO0 #CARTCellTherapy https://t.co/SeBZFdFisi
Dr. John Cush @RheumNow ( View Tweet )
49 minutes 50 seconds ago
The Hidden Cost of Gout For many people, gout is viewed as an episodic disease: a painful flare, a short course of treatment, and then life returns to normal. However, as rheumatologists, we know that recurrent attacks can lead to joint damage and tophi if left untreated. https://t.co/BfZFBZ8YrU
Dr. John Cush @RheumNow ( View Tweet )
2 hours 19 minutes ago
Primary biliary cholangitis is a chronic cholestatic disease characterized by autoimmune-mediated destruction of bile ducts, leading to fibrosis, cirrhosis, & liver failure. Ursodeoxycholic acid is 1st line Rx. New Rx include elafibranor & seladelpar (activates peroxisome https://t.co/tKloXvJYek
Dr. John Cush @RheumNow ( View Tweet )
18 hours 20 minutes ago
UK primary care database (2000–21) gout study of new colchicine initiators (n 31,478) vs noninitiators (mean 60 yrs, BMI 30), follow-up of 4.5 yrs. Colchicine use had a signif. 12% lower risk of Joint Arthroplasty (HR 0.88); 23% lower TJA in knee/hip OA (HR 0.77) https://t.co/bT07lUYBB2
Dr. John Cush @RheumNow ( View Tweet )
20 hours 20 minutes ago
"Gout, unlike any other disease, kills more rich men than poor, more wise men than simple." — Thomas Sydenham

Dr. John Cush @RheumNow ( View Tweet )

22 hours 19 minutes ago
GI dz & malnutrition in scleroderma (SSc) is common, assessed by BMI. Among 450 SSc (F/U 5.3 yrs), lower BMI were significantly assoc w/ pseudoobstruction, smaller oral aperture, higher Medsger vascular severity scores. Defines those at risk https://t.co/JY9YFOWE5C https://t.co/xFZ0rCXjQv
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
Gout and its' associated comorbidities - treat gout and its' comorbidities to target Created by : @Rheumat_aravind https://t.co/AKT3rAvDBH https://t.co/SM248IPadR
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
RheumIQ: True or False: Severe allergic reactions to allopurinol are more common in patients with chronic kidney disease than in the general population. See if you got it right at https://t.co/LATb1P18Sh. https://t.co/dFdrhso1oU
Dr. John Cush @RheumNow ( View Tweet )
1 day 19 hours ago
Persistence of education and monitoring is crucial to optimal gout management Optimal gout care is dependent on having a well-informed health care provider who recognizes and follows the ACR gout management recommendations. It is important that the misconceptions and myths held https://t.co/XYSwvuihjJ
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
Patients with anemia (10% of the population) have a 2-fold increased risk of gout. For more gout content, follow our Gout: More than Flares campaign at https://t.co/lQoiFjubZJ, https://t.co/s8HeS9sbu0
Dr. John Cush @RheumNow ( View Tweet )
1 day 23 hours ago
Expert Perspective on Calcium Pyrophosphate Deposition Disease A current perspective article by Dr. Sara Tedeschi tackles many unresolved issues around CPPD diagnosis, classification, and management, including the lack of clinical trials or FDA approved treatments. https://t.co/zxJ9aQweNl
Dr. John Cush @RheumNow ( View Tweet )
2 days ago
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