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JAKi Safety and Efficacy in bDMARD-IR Patients With RA This ACR 2023 poster shows SELECT-CHOICE outcomes through Week 204 from bDMARD-IR patients with RA, including TNFi-IR subgroup outcomes. Sponsored by AbbVie US Medical Affairs. https://t.co/OOZOSb9Bye https://t.co/tA4wCAWOS8
Dr. John Cush @RheumNow ( View Tweet )
53 minutes 3 seconds ago
Immunosuppression Increasing Dr. Jack Cush reviews the news and journal reports from the past 2 weeks on https://t.co/V10S4oVFsv; but begins with a discussion of what constitutes "immunosuppression" and how it applies to our patients. https://t.co/KvZIiKowox https://t.co/cbBYydVQbB
Dr. John Cush @RheumNow ( View Tweet )
2 hours 50 minutes ago
Experts and patient discuss ear, nose, and throat manifestations in severe active granulomatosis with polyangiitis. This therapeutic update is sponsored by Amgen US Medical Affairs. https://t.co/LPiw3ztZQw

Dr. John Cush @RheumNow ( View Tweet )

4 hours 39 minutes ago
Single center study of 163 pts (mostly RA) Rx w/ tocilizumab found 41 hospitalized & 49% for serious infx. SIE were more common w/ eosinopenia (EC < 0.05 g/L; avg (0.06 vs 0.20 g/L) & low ratio EC/NC ratio (× 1000 < 11.8) (median (6.54 vs 48.50). https://t.co/88sbHBIhXt https://t.co/6wUeqSbVxx
Dr. John Cush @RheumNow ( View Tweet )
4 hours 53 minutes ago
No clear link between weather & MSK symptoms There is a belief that changes in weather conditions, such as impending rain or temperature, can trigger or worsen muscle and joint pain but Australian researchers have found no clear pattern between the two. https://t.co/V3rfCTWRBQ https://t.co/eFdZH4LoNA
Dr. John Cush @RheumNow ( View Tweet )
17 hours 53 minutes ago
CD19 CAR T-Cell Therapy in Autoimmune Disease The NEJM has published the results of CD19 B cell depletion (by CAR-T cell therapy) in autoimmune disease patients, demonstrating it to be feasible, safe, and efficacious. https://t.co/ym3pAsI5Sf https://t.co/AnfKOISscV
Dr. John Cush @RheumNow ( View Tweet )
19 hours 52 minutes ago
RA BIOBADASER registry study of 1128 patients going on ts/bDMARD found 107 (9.3%) w/ multimorbidity (Charlson Comorbidity index ≥ 3). Multimorbid RA were older, more SJC & signif higher DAS28; ts/bDMARD retention rate equal groups https://t.co/am4Uoccla9 https://t.co/P7Ae2Jal2e
Dr. John Cush @RheumNow ( View Tweet )
20 hours 52 minutes ago
Feb 2024 EMA meeting approved biosimilar ustekinumab (Pyzchiva) for adult/pediatric psoriasis; psoriatic arthritis; UC/Crohn's. & also approved generic Apremilast Accordfor the treatment of psoriatic arthritis, psoriasis, and Behçet disease https://t.co/Cu9f4qQjgP https://t.co/qmH3ZkfReN
Dr. John Cush @RheumNow ( View Tweet )
21 hours 29 minutes ago
Congratulations to Drs. David Felson Tuhina Neogi of Boston University in being awarded a U19 5 yr grant to fund Novel Insights into Osteoarthritis, Pain and Function: The Multicenter Osteoarthritis (MOST) Study. https://t.co/fGU9Zk2ECs https://t.co/dtT0hu7aA1
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
MMPs play pathogenic role in RA-ILD. Multicenter VA study of 2,312 RA pts, 96 had prevalent ILD & Incident ILD developed in 130 (IR 7.5/1,000PY). High MMP-7 increased ILD (adj OR 3.78) & incident ILD (adj HR 2.33). Higher MMP-9 did same https://t.co/3i49TsAQbt https://t.co/RA6Fu2jPeE
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
Eating for RA The majority of practicing rheums at RheumNow Live were unaware of the new ACR guidelines issued in 2022 regarding dietary and lifestyle recommendations for patients with RA. Dr. Monica Guma reviewed these guidelines during her lecture. https://t.co/9herN2musx https://t.co/P1xJn2lDrg
Dr. John Cush @RheumNow ( View Tweet )
1 day 4 hours ago
Serial plasma samples assayed for 92 inflammation-related proteins, during and after gout attacks. 21 were differentially expressed. Gout flares assoc w/ increased IL-6, CSF-1, VEGF-A & tumour necrosis factor superfamily 14 (TNFSF14 was highest) https://t.co/2p8vTFcmvD https://t.co/5z1gYdsKJO
Dr. John Cush @RheumNow ( View Tweet )
1 day 22 hours ago