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COVID-19 Arthropathy and Myalgia

Sep 30, 2022

An online survey of random COVID-19 infected persons shows that arthralgia and myalgia are common consequences to COVID-19 infection.

Like other alphaviruses, the coronavirus has been reported to result in numerous musculoskeletal complaints. Researchers assessed the prevalence of

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Opioid Crisis Costs USA $1.5 Trillion

Sep 29, 2022

Reuters has reported the results of a Congressional report showing the economic toll of the opioid addiction and overdose crisis on the United States reached nearly $1.5 trillion in 2020 alone and is likely to grow.

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Analyses of data from the Nurses Health Study (1986-2016) & NHSII (1989-2017) cohorts shows chronic low sleep duration (< 5hrs/night vs >7hr/night) was assoc w/ increased SLE risk (adj HR 2.47). Low sleep also assoc w/ body pain(2.13), depression(HR 2.82)

Immune Benefits to Sound Sleep

Sep 26, 2022

The revitalizing powers of sleep are numerous but what are the consequences to inadequate sleep? A current report in the Journal of Experimental Medicine shows the connection between sleep and immune function as measured in mice and humans; specifically, a good night’s sleep promotes normal

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USPSTF Recommends Screening for Anxiety and Depression

Sep 22, 2022

The U.S. Preventive Services Task Force has recommended that general practitioners actively screen and identify anxiety and depression in all adult patients under 65 yrs.

The USPSTF was appointed by the Department of Health and Human Services, and has been working on this guideline

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Yoga Fails to Benefit Knee Osteoarthritis

Sep 20, 2022

The Annals of Internal Medicine has published a study showing online yoga education and an unsupervised yoga program may improve physical function did not improve knee pain after 12 weeks and 24 weeks.

The study included 212 adults with symptomatic knee osteoarthritis who were

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Propensity matched pairs (n=237 872) of perioperative pts - gabapentin users and nonusers shows perioperative gabapentin use had significantly more delirium (RR 1.28), antipsychotic Rx (1.17 ) & pneumonia (1.11) vs nonusers post surgery
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CD19 CAR T Cell Therapy in SLE (9.16.2022)

Sep 16, 2022

The big news this week: the approval of deucravacitinib (a new class of drug?) for psoriasis; the 2022 ACR guidance on glucocorticoid-induced osteoporosis; a national poll of older adults over the age of 50 who claimed self-reported or doctor-diagnosed arthritis; and much more. Let's review

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2022 Univ of Michigan Natl Poll on Healthy Aging finds that 70% of older adults reported joint pain (more in Women 75% vs 65%M). 30% have a HCP dx of #OA, 8% RA, 7% gout or pseudogout & 5% w/ another kind of arthritis

70% of Older Adults Report Joint Pain

Sep 14, 2022

Dr. Beth Wallace and colleagues at the University of Michigan surveyed a national sample of older adults (50–80 yrs) and found that 70% currently report experiencing joint pain and 60% reported being told by a health care professional that they have arthritis. 

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The 2022 ACR abstracts are published and posted for you. Let the Learning begin!
Rheums! Have a Rheumatology question or case for Jack Cush? Record it here and we may feature it on an upcoming podcast. Tell us your name and where you practice rheumatology.
B12 or Placebo effect? Open label study of B12 (1000mcg/d) in 29 fibromyalgia pts showed after 50d, significant reductions in FM Impact Quest. (FIQR; 49.8 to 40.00; p< 0.01), Function, Sxs, anxiety scores all signif improved.
Longitudinal study of 411 adult fibromyalgia pts showed that 73.2% had depression at enrollment. Higher depression scores at baseline predicted poorer functional outcomes. Effectively treated depression resulted in improved functioning at follow-up.
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Goofy But True

Sep 02, 2022

Dr. Jack Cush discusses declining survival rates in the USA, FDA approvals of new COVID subvariant boosters and other odd and possibly true new research reports from the past week on

  1. After historic drop in 2020 (COVID), life expectancy in USA dropped again,

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Hypertension Associated with RA and OA

Sep 02, 2022

While hypertension and arthritis are very common disorders, the association between them is unclear.  Analysis of NHANES data suggests that both rheumatoid arthritis (RA) and osteoarthritis (OA) are strongly associated with hypertension (HTN).

The NHANES (National Health and Nutrition

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Study of 497 pts referred by general practitioners to rheumatologist (2018-19) showed: - GP Dx changed by Rheum in 58% - Low complexity Dx (FM, OA) acct for 50% referrals - 46% of referrals inappropriate - GP correlations w/ Rheum Dx poor (κ < 0.5)
OPTION-DM study of 140 diabetic neuropathy pts Rx for 16 weeks w/ one agent (& if no response) an add-on agent. At wk 16, all 3 regimens lowered nerve pain score from 6.6 to 3.3 w/ no difference between Elavil+Lyrica, Lyrica+Elavil, o Cymbalta+Lyrica)
✅ Probably one of my most important slides ⬇️ WHY IS MY #TREATMENT NOT WORKING (or not working enough) 😭 This is really a question we're dealing with everyday in #rheumatology when taking care of patients with #autoimmune and other rheumatic diseases 👍

Prevalent Sleep Problems in Rheumatoid Arthritis

Aug 30, 2022

Data from Data FORWARD (The National Databank for Rheumatic Diseases) reveals that nearly two-thirds of rheumatoid arthritis (RA) patients have self-reported sleep problems.

The FORWARD study, a registry that includes over 4200 RA patients), collects data on obstructive sleep apnea (

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Hyaluronic Acid Knee Injections Equivalent to Placebo

Aug 25, 2022

In the United States, where over $300 million is spent annually on intraarticular hyaluronic acid injections, yet another study shows such therapy to be no better than placebo.

BMJ has published a metanalysis of the efficacy and safety of viscosupplementation (intraarticular

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Record Use of Marijuana and Hallucinogens in Young Adults

Aug 24, 2022

The NY Times reports that a recent survey of drug use indicates that daily consumption of marijuana among young adults nearly doubled in the last decade. This is coupled with growing mainstream acceptance of cannabis and hallucinogenic compounds.

A national survey conducted by the

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Weight Loss Slows Knee OA Progression

Aug 23, 2022

Declines in body mass index (BMI) were linked with slower worsening of knee osteoarthritis (OA), according to data from three large longitudinal cohort studies.

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Melatonin Use Growing, Inappropriate & Potentially Unsafe With nearly 1/3 of adults, adolescents and children having sleep difficulties, many resort to using melatonin. But is it effective, safe and warranted?
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Managing JDM with Calcinosis

Aug 19, 2022

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow and discusses a case of refractory juvenile dermatomyositis with calcinosis.

  1. CDC report of fungal infx in US 2019 - coccidioidomycosis (20,061), histoplasmosis (1,124) & blastomycosis (240

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