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Fibromyalgia/Pain

The Last CBD Trial: Dr. David Liew ( @drdavidliew) discusses abstract #1456 presented at the #ACR21 annual meeting.https://t.co/Kw3h2vTJkv https://t.co/WZGV7iOFlA
Dr. John Cush @RheumNow( View Tweet )
Nov 24, 2021
Fibromyalgianess Glucocorticoid Persistence in RA Patients: Dr. Sheila Reyes ( @RHEUMarampa) discusses abstract #0120 presented at the #ACR21 annual meeting.https://t.co/9yOM5rSARv https://t.co/Gq2YxbxkmM
Dr. John Cush @RheumNow( View Tweet )
Nov 09, 2021
Interesting results where cannabidiol NEG results in RCT in hand OA and PsA. ? Throw out the ‘pot’with the dish water? Did it stimulate appetites? Was pain the same but interference less? Abst#1456 #ACR21 @RheumNow https://t.co/rnz82Paxkr
Nov 08, 2021
#ACR21 Ab#1166. How many of your pts use marijuana? ⭐️Probably more than you think! ▶️57% have tried, >50% use at least weekly ▶️67% doctors thought <20% of pts use it 🔥Pts over 40 yo MORE likely to report marijuana use @Rheumnow https://t.co/0uW8rZvf1k https://t.co/ShMnR0faHr
Nov 08, 2021
Telemedicine black computer

Can tender and swollen joint counts work in a telemedicine world?

Nov 08, 2021

In a world where telemedicine and virtual care are not going away, is there value in patients assessing their own tender and swollen joints?



Work from the Canadian Early Arthritis Cohort (CATCH, @earlyarthritis) presented by Dr. Vivian Bykerk (@BykerkVivian) is the subject of two

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Sublingual Cyclobenzaprine for fibromyalgia. It seems to improve pain, and across the board on secondary endpoints. But all by a modest effect. Big placebo response also. Not time to get overly excited yet. Abstr#0477 #ACR21 @RheumNow https://t.co/aUtwaH5oEh
Richard Conway @RichardPAConway( View Tweet )
Nov 06, 2021
@BethIWallace et al. on fibromyalgianess and GC in #rheumatoidarthritis pts. Accdg to their study, pts w/⬆ levels of fibromyalgianess at BL had higher odds of GC persistence on ffup. Something to consider when evaluating need for GC adjustment. @RheumNow #ACR21 abs0120 https://t.co/MTWEXGHJ2n
Nov 06, 2021
Study by @BethIWallace @Tuhina_Neogi shows that we seem to treat fibromyalgia symptoms with steroids in RA patients. Its a bad idea in fibromyalgia, and has got to be bad practice in RA too. Abstr#0120 #ACR21 @RheumNow

Richard Conway @RichardPAConway( View Tweet )

Nov 06, 2021
DNA,genotyping,gene,sequencing

Large GWAS Study Reveals Genetic Basis for Osteoarthritis Phenotypes

Oct 29, 2021

Cell has published the results of a multinational, GWAS meta-analyses of 826,690 individuals that included 177,517 osteoarthritis patients, finding 52 previously unknown osteoarthritis (OA) genetic risk variants and linking OA genetic risks with joint distribution and pain-related

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RheumNow Podcast – Like Father, Like Daughter (10.29.2021)

Oct 29, 2021

Bad things happen when our patients go into the ICU and it's not always due to the disease. Good things happen when we rise from sitting. And guess what? Rheumatologists are setting cardiology straight about hydroxychloroquine and chloroquine. This, and a special recognition of parent-child

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ankle,xray

Platelet-Rich Plasma Injections Fail in Ankle Osteoarthritis

Oct 27, 2021

A controlled trial of intra-articular platelet-rich plasma (PRP) injections into the ankle of osteoarthritis (OA) patients failed to improve ankle symptoms and function when compared to placebo injections - yet another trial showing that intraarticular injections are seldom beneficial.

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Hip

Pfizer/Lilly Pull Tanezumab Development

Oct 26, 2021

Today, Lilly and Pfizer announced their global clinical development of the NGF inhibitor, tanezumab, has been discontinued due to recent negative opinions from the EMA and FDA advisory committee.



This decision mirrors that of other companies (AbbVie, AstraZeneca, Johnson & Johnson

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ICYMI: Propensity matched comparison of Tramadol vs Codeine use. Tramadol had a signif. higher risk of all-cause mortality (HR, 2.31), CV events (HR 1.15) & fractures (HR 1.50), but no diff in falls, delirium, constipation, opioid abuse, sleep disorders. https://t.co/nBUe5VV1D3 https://t.co/C3r0Fur4xJ
Dr. John Cush @RheumNow( View Tweet )
Oct 24, 2021
ICYMI:Pregabalin (lyrica) for Fibromyalgia 75 mg bid; may be increased to max dose 450 mg/d.(Reduce for renal dz). Indications: DM neuropathy/pain, post-herpetic neuralgia, partial seizures. Rare AE: Angioedema, low Plts, ^PR interval, rhabdo, gynecomastia https://t.co/r4cH7n9qWD

Dr. John Cush @RheumNow( View Tweet )

Oct 23, 2021
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RheumNow Podcast – Rheumatologist Smoke-Enders (10.22.2021)

Oct 22, 2021

Today I have a few questions: Is tramadol really a weak narcotic? Should we really still be doing placebo-controlled trials? What are we going to do about our patients who are smokers? This and more, in this week's review of the news and journal articles.

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Fluorosis presenting as lower back pain and stiffness of the neck, shoulders, hips, yellowish-brown tooth discoloration, LOM of Cx spine, hips, shoulders. Pelvic Xrays showed osteosclerosis without sacroiliitis. T scores were +12.1 LS spine, alk phos =479 https://t.co/t2lmoudUIM https://t.co/1pnXJkoCOn
Dr. John Cush @RheumNow( View Tweet )
Oct 17, 2021
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RheumNow Podcast – Quackademia (10.15.2021)

Oct 14, 2021

Dr. Jack Cush reviews the FDA approvals, news and the latest journal articles from the past week on RheumNow.com.

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Epi-4 studies of 4,376 military service persons shows the prevalence of fibromyalgia = 2.9% predeployment, but was significantly higher in those with postemployment PTSD (10.8%) (not without PTSD-0.8%) but higher if in PTSD RCTs (40%) https://t.co/95tCsMtoyw https://t.co/DpMQqPVfhP
Dr. John Cush @RheumNow( View Tweet )
Oct 08, 2021
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RheumNow Podcast – #ACA: Ask Cush Anything (10.8.2021)

Oct 08, 2021

Arthritis numbers are rising, and people are finally talking about osteoarthritis. Also, ACR 2021 is just a few weeks away - are you ready? Finally, I'll review cases and questions submitted by viewers in Ask Cush Anything (#ACA). This, and nearly a dozen news items and reports, are discussed in

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obesity.knee_.arthritis.jpg

Prevalence of Arthritis Rising in the USA

MMWR
Oct 07, 2021

The latest CDC estimates of the national prevalence of arthritis and arthritis-attributable activity limitations (AAAL) show a continued increase in absolute number: 58.5 million (23.7%) U.S. adults have arthritis, 25.7 million (43.9%) of whom have AAAL. 

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bouchard.JPG

Erosive Hand Osteoarthritis Portends Worse OA

Oct 06, 2021

An erosive hand osteoarthritis (EOA) study from the Osteoarthritis Initiative shows that EOA is more common in older women and is strongly linked to further progressive, articular structural damage.

This was a longitudinal cohort study of 3,365 individuals without prevalent erosive hand OA at

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ASK CUSH ANYTHING! Rheums: Have a question for Dr. Cush? Record it here and we may feature it on an upcoming podcast. #RheumNowhttps://t.co/wzNmOzH4VE https://t.co/KzPzWpSoW1
Dr. John Cush @RheumNow( View Tweet )
Oct 06, 2021
knee2_0.JPG (keep)

AAOS Clinical Practice Guideline for Knee Osteoarthritis

Oct 04, 2021

The American Academy of Orthopaedic Surgeons has published their Clinical Practice Guideline for Management of Osteoarthritis of the Knee (Non-Arthroplasty); updating 19 of the 29 evidence-based recommendations and focuses on nonsurgical treatmentss to provide pain and patient function.

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tylenol,acetaminophen,pills,tablets

Is Acetaminophen Potentially Hazardous in Pregnancy?

Sep 27, 2021

A consensus report from a multinational group of 91 scientists, clinicians and public health professionals alarmed the medical world last week as they suggest the use of acetaminophen (paracetamol) during pregnancy may have hazardous developmental effects on the fetus.



Tylenol (

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