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Noninflammatory Pain Persists in RA Despite Treatment

Jun 02, 2020

Almost one-third of patients with new-onset rheumatoid arthritis (RA) reported persistent unacceptable pain after 21 months of combination therapy, according to a study by Swedish researchers.A total of 29% of patients continued to have unacceptable pain.

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Targeting the Wnt Pathway Fails in OA

May 28, 2020

The Wnt pathway modulator lorecivivint failed to meet the primary endpoint in a phase IIa study for knee osteoarthritis (OA), but showed promise in certain patient subgroups, researchers reported.

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Metanalysis of 9 clinical trials and 1014 patients fails to show added value of subacromial decompression surgery (for subacromial pain syndrome) over sham surgery or exercise but a small risk of harm from having surgery.

Dr. John Cush RheumNow ( View Tweet)

May 20, 2020

New ACR Guidelines for Gout Management

May 12, 2020

The ACR has published the 2020 guidelines on the management of gout that includes strong recommendations favoring treat‐to‐target management and starting urate lowering therapy (ULT) for patients with frequent flares, radiographic damage or tophi due to gout.

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Physical Activity Prevents Hospitalization

May 06, 2020

Modifiable lifestyle choices can impact long term health.  A recent study shows that usual and increased physical activity can results in less hospitalization amongst the the general population.

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ACR: In-Person Urgent vs. Virtual Non-Urgent Medical Care

May 05, 2020

On April 26, 2020 the American College of Rheumatology (ACR) published a guidance paper to assist rheumatologists and rheumatology health professionals in assessing the need for urgent or face-to-face medical care versus virtual or telehealth patient care.  The driving principals being the

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German Society of Rheumatology COVID Pandemic Recommendations

Apr 30, 2020

The Annals of Rheumatic Disease has published the preliminary recommendations of the German Society of Rheumatology for the management of Inflammatory rheumatic diseases patients during the SARS-CoV-2/Covid-19 pandemic.

These preliminary recommendations are based on an expert consensus from 17

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FDA Consumer Warnings on Cannabis and CBD

Apr 23, 2020

The FDA issued a new consumer update on what you need to know about Cannabis or Cannabis-derived Compounds, Including CBD. This is part of the FDA effort to answer questions about the science, safety, and quality of products containing cannabis and cannabis-derived compounds, particularly CBD

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Physical Therapy Superior to Steroid Injection for Knee OA

Apr 16, 2020

Treatment options for painful knee osteoarthritis (OA) are numerous, but comparative outcomes are seldom available. A NEJM report shows that physical therapy is superior to intraarticular glucocorticoids injections assessing the outcomes 12 months after the intervention. 


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ACR COVID-19 Guidance for Rheumatic Disease Patients

Apr 14, 2020

On April 11th, the ACR Board of Directors approved a COVID-19 guidance document written by an ACR task force charged with updating and clarifying recommendations for rheumatologists and rheumatic disease patient management during the current COVID-19 crisis.

This ACR release, in its

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Tanezumab: A Win as Last-Ditch Osteoarthritis Tx

Apr 07, 2020

A phase III study of the nerve growth factor and monoclonal antibody tanezumab showed positive results in a refractory patient population with knee or hip osteoarthritis (OA) -- good enough that this agent may finally be approved after a long and rocky development road.

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NICE Guidelines on Managing Rheumatologic Conditions During COVID-19 Pandemic

Apr 07, 2020

On April 3rd, the National Institute for Health and Care Excellence (NICE) in the UK, published a rapid guideline for managing children and adults with rheumatological autoimmune, inflammatory and metabolic bone disorders during the COVID-19 pandemic, while protecting staff from infection.

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The Immunologic Basis of Wellness in the COVID-19 Era

Apr 06, 2020

We indeed are living in interesting times and we all are seeking not to contract COVID-19 - this is logical. While our goal is to avoid infection, I think we all must agree that our aspirations must encompass more than disease avoidance. What we should be seeking now, as well, is more than

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Global Rheumatology Alliance Registry Will Study COVID-19

Mar 23, 2020

In the midst of a global pandemic of the 2019 Novel coronavirus acute respiratory disease (COVID-19), a small handful of Rheumatologists gathered on social media to collectively grapple with the impact of this virus on vulnerable populations with rheumatic disease.

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COVID-19 Rheumatology News

Mar 19, 2020

With the COVID-19 pandemic dynamically changing, we have provided several news items germane to the Rheumatologist.

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The COVID-19 Global Rheumatology Registry

Mar 17, 2020

As the highly virulent SARS-CoV-2 spreads over the world, uncertainty and fear for our patients with rheumatic diseases mount.  

As of March 17, 2020 over 183,000* cases of Coronavirus disease 2019 (COVID-19) have been recorded, with the majority in China and Europe, but that may be the

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Diabetes in OA: Pain Is Worse

Mar 09, 2020

Among patients with knee osteoarthritis (OA), pain was greater for those with coexisting diabetes mellitus (DM), and this association was independent of obesity and radiographic severity, European researchers found. 

In an analysis that adjusted for age, sex, body mass index (BMI), and

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RheumNow Podcast - Despite Corona (3.6.20)

Mar 06, 2020

Dr. Jack Cush reviews the news and journal articles from the past week on

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Need for Disruptive Innovation in Rheumatology

Mar 05, 2020

A full-read, novel Viewpoint article published in the Annals of Rheumatic Disease (Huizinga TWJ, et al) spotlights a recent international meeting of big thinkers, scientific collaborators and industry dedicated to innovation in rheumatology.

Citing examples of developing disruptive

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Drug Interactions with Cannabinoids

Mar 04, 2020

Cannbinoids are widely available and used for a variety of indications, but little is known about their safety and their potential for drug interactions. The Canadian Medical Journal has published a review of drug interactions with cannabinoids, many of which are mediated by cytochrome-P450

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RheumNow Podcast- Methotrexate Mechanisms (2.28.20)

Feb 28, 2020

Dr Jack Cush Reviews the news and journal articles from the past week on

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Fatigue Looms Large in Lupus

Feb 27, 2020

Fatigue is an important component of the disease experience in systemic lupus erythematosus (SLE), and can have a profound impact on patients' perception of well-being, Italian researchers reported.

Median scores on the Functional Assessment Chronic Illness Therapy (FACIT)-fatigue scale

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RheumNow Podcast - RWCS Quick Hits (2.14.20)

Feb 14, 2020

Dr. Jack Cush reviews the highlights from the 2020 RWCS meeting in Maui, Hawaii.

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Half of Opioids Rx Come from 1% of MDs

Jan 31, 2020

The BMJ reports that while most US providers are cautious in their prescribing, half of opioid prescriptions are written by 1% of providers.

Between 2003 and 2017, there was an annual average of 669495 providers prescribing 8.9 million opioid prescriptions.

In 2017, 1% of

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NSAIDs May Impair Healing if Taken Nightly

Jan 27, 2020

A new study in Scientific Reports suggest that circadian rhythms play an important role in wound healing, and that nonsteroidal anti-inflammatory drugs (NSAIDs) may be disruptive if taken at night given primary healing that occurs in a body at night. 

NSAIDs provide analgesic

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