Fallen Angels (1.17.2025)
Dr. Jack Cush reviews the news and journal reports from the past week on https://t.co/V10S4oVFsv; and pays homage to colleagues who passed away in 2024.
https://t.co/1DvtGbUHEk https://t.co/EnZ8D6xzgk
Dr. John Cush @RheumNow( View Tweet )
We must learn to live together as brothers or perish together as fools.
Martin Luther King Jr. (1929 - 1968) https://t.co/3mWHhPY5rH
Dr. John Cush @RheumNow( View Tweet )
"I'd rather be a failure at something I love than a success at something I hate."
- Martin Luther King Jr. https://t.co/E2f5mEV9Jx
Dr. John Cush @RheumNow( View Tweet )
Challenging the status quo is difficult, and worth it. Happy Birthday.
-Seth Godin https://t.co/xVgdC8wJnD https://t.co/Mdtm9XwOs9
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Dr. John Cush @RheumNow( View Tweet )
U.S. overdose deaths far outpace other countries. In 2023 US drug overdoses >100,000 for 3rd year — a >50% jump since 2019. 2022 rate=324/1 million. High rates attributed to fentanyl, polysubstance use, counterfeit pills, variance in state policies on harm reduction… https://t.co/IYpytkEgpt https://t.co/HrrU9SCJT1
Dr. John Cush @RheumNow( View Tweet )
QD Clinic - Treating Overlap with ILD
Polyarthritis, ILD, Dermatomyositis - how to treat?
Features Dr. Jack Cush.
QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025
Register at https://t.co/2dcFVgu8z6
https://t.co/CsIpdS8hyd https://t.co/I92p5U3UTp
Dr. John Cush @RheumNow( View Tweet )
QD Clinic - Acute Neck & Back Pain
Acute onset febrile, polyarthritis, neck and low back pain
Features Dr. Jack Cush.
QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025
Register at https://t.co/2dcFVgu8z6
https://t.co/2GqyqXAjbF https://t.co/vIeqdHyayV
Dr. John Cush @RheumNow( View Tweet )
2024 In Memorium
Sadly, in 2024, Rheumatology lost many of our greatest brethren, mentors, do-gooders and clinicians. These clinicians were responsible for the care of hundreds of thousands with MSK problems, while driving the scientific advances that will shape the lives of… https://t.co/c8xvPyXbft https://t.co/TEQihNmZnr
Dr. John Cush @RheumNow( View Tweet )
Eltrombopag, a Potential New Treatment for ITP
A pilot trial has shown a thrombopoietin receptor agonist, eltrombopag (Promacta), to be effective in connective tissue disease-related (CTD), refractory immune thrombocytopenia (ITP).
https://t.co/hYSAEKOjq5 https://t.co/QzBNA3SWVo
Dr. John Cush @RheumNow( View Tweet )
Pan American Health Org announces that in 2024 saw largest dengue epidemic in the Americas, >12.6 million cases reported (3x record in 2023); 21,000 severe w/ 7,700 deaths; 90% from Argentina, Brazil, Colombia, Mexico. Most USA cases (FL, HI, TX, AZ, CA) seen in travelers… https://t.co/nhuJIP9Y8v https://t.co/QLju8uRKZ8
Dr. John Cush @RheumNow( View Tweet )
Just published, a new review of Axial spondyloarthritis from Baraliakos, et al in Lancet! https://t.co/AuMTLo8iQO https://t.co/1icGoXKfB9
Links:
Dr. John Cush @RheumNow( View Tweet )
RheumThoughts: Overlap Syndrome with ILD
How would you manage a patient with Overlap (anti-synthetase) syndrome, ILD, polyarthritis and myositis?
https://t.co/4RyV1zkphe https://t.co/qTZ4JYlJmW
Dr. John Cush @RheumNow( View Tweet )
U.S. overdose deaths far outpace other countries. In 2023 US drug overdoses >100,000 for 3rd year — a >50% jump since 2019. 2022 rate=324/1 million. High rates attributed to fentanyl, polysubstance use, counterfeit pills, variance in state policies on harm reduction… https://t.co/oHtiMytdtR https://t.co/DLFPYEkdRC
Dr. John Cush @RheumNow( View Tweet )
Systematic review of 208 pts w/ IgG4–related disease & pachymeningitis - mean age 52 yrs; 2/3 male. HA & cranial nerve dysfunctions were most common Sxs. nearly half had systemic Dz. Abnl imaging of cavernous sinus and middle fossa. Incr. IgG4 in 65% w/ CSF pleocytosis in 52%… https://t.co/0TberfIXsH https://t.co/6k5QgGTnkw
Dr. John Cush @RheumNow( View Tweet )
Marketscan claims data study assessed fall risk in 57 086 older adult starting gabapentin vs duloxetine & found gabapentin was not associated with increase in falls. At 6-mos, gabapentin had lower risk of falls (HR 0.52; 0.43 to 0.64]. https://t.co/agrdzkxNdL https://t.co/Te981iDMZU
Dr. John Cush @RheumNow( View Tweet )
Prevalence of Autoimmune Diseases in the United States
An epidemiologic assessment of the prevalence of autoimmune diseases in the United States (US) finds that nearly 5% of the population has an autoimmune disorder, twice as many in women compared to men.… https://t.co/L5BusRvcFP https://t.co/JTw8CXf1Tq
Dr. John Cush @RheumNow( View Tweet )
Spanish registry ARTESER, looked at GCA outcomes from 2013 to 2019. In 1200 GCA pts ~ 2 yrs F/U, The 5-Yr mortality 37.9/1000 pt/yrs; higher in males vs females (59 vs 29 p<0.001), but was same as gen population . Incr mortality w/ age & male sex. HA & Hgb were protective… https://t.co/idnuUL9Kog https://t.co/2MsOxuTtCd
Dr. John Cush @RheumNow( View Tweet )
Rheumatologist Survey: Active Lupus on pred + DMARD w/ (more than skin/Joint) organ & serologic activity- whats your preferred "add-on" drug?
Dr. John Cush @RheumNow( View Tweet )
Retrospectively review of 165 #EGPA pts, GI manifestations were assoc w/ Eosinophils > 19.5%, weight loss, & myalgia; & included abdominal pain (78%), diarrhea (40%), N/V (33%); GI hemorrhage (27%), ulcers (17%), obstruction (10%), & pancreatitis (6%) https://t.co/EzsGcFs2l2 https://t.co/mQrgjTG6NV
Dr. John Cush @RheumNow( View Tweet )
Full read JAMA ILD Review article. ILD= 33% idiopathic (IPF) + 15% hypersensitivity pneumonitis + 25% from CTD.
30% of ILD has cough
Chest CT 91% sensitive, 71% specific
5% decr in FVC/12 mos assoc w/ 2-fold incr in mortality
Rx options nintedanib or pirfenidone, TCZ, MMF, RTX… https://t.co/s5v3XD8QmC https://t.co/iP5yFWkQwb
Dr. John Cush @RheumNow( View Tweet )
Online survey of 1,531 in 2019 showed that rural women have greater psychological and physical burdens than their suburban/urban women - with more mood swings, muscle and joint pain, vaginal dryness and urinary problems . https://t.co/TlaEEENdzp https://t.co/TTtyWK5urZ
Dr. John Cush @RheumNow( View Tweet )
Algorithm for the treatment of calcinosis #calcinosis @RheumNow #ACR24 https://t.co/NZhP7Enzrp https://t.co/1mO8waM5DI
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Dr. John Cush @RheumNow( View Tweet )
Best of 2024: Mixed Long-term Effects of Calcium and Vitamin D in Postmenopausal Women
https://t.co/rFOW4OpZS7 https://t.co/A0EN8b9KYB
Dr. John Cush @RheumNow( View Tweet )
Full read JAMA ILD Review article. ILD= 33% idiopathic (IPF) + 15% hypersensitivity pneumonitis + 25% from CTD.
30% of ILD has cough
Chest CT 91% sensitive, 71% specific
5% decr in FVC/12 mos assoc w/ 2-fold incr in mortality
Rx options nintedanib or pirfenidone, TCZ, MMF, RTX… https://t.co/FKZyNU1s06 https://t.co/w5q0hOesEH
Dr. John Cush @RheumNow( View Tweet )
What is Osteoarthritis? A downloadable patient education page from JAMA. https://t.co/PfoimFgxRp https://t.co/WVQbofTzGC
Dr. John Cush @RheumNow( View Tweet )
Recent Blogs
How would you manage a patient with Overlap (anti-synthetase) syndrome, ILD, polyarthritis and myositis?
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