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General Rheumatology

“Math has no opinion” - Mellody Hobson

Dr. John Cush @RheumNow( View Tweet )

Efgartigimod Efficacy in Idiopathic Inflammatory Myopathy Today Argenx announced the results of their Phase 3 "ALKIVIA" study; demonstrating efficacy and safety of subcutaneous efgartigimod for Idiopathic Inflammatory Myopathy (IIM, AKA inflammatory myositis). https://t.co/9tgAM8YVh1
Dr. John Cush @RheumNow( View Tweet )
Misdiagnosis of Still's Disease High fever, strange rashes, scary labs often lead to a consideration of Still's disease (AOSD or systemic JIA). Yet the dramatic onset of a systemic disorder may overlap with another, and possibly as rare, systemic disorder that should not be https://t.co/mCbNBAt9T5
Dr. John Cush @RheumNow( View Tweet )
Latest #s: EHR estimates from 6 large US medical systems, estimated prevalence of autoimmune Dz (AID) to be >15 million (4.6% US population); 34% have > 1 AID. Women have 2x risk. Sex ratio of 1.7:1 F:M. https://t.co/tfSCpRqHbY https://t.co/VckjIoGOaa
Dr. John Cush @RheumNow( View Tweet )

A Tribute to Thomas A. Medsger Jr., MD (1936–2026)

The rheumatology and scleroderma communities mourn the loss of Dr. Thomas A. Medsger Jr., who died August 15, 2026, in Pittsburgh, at age 89.

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Nonrigid lumbar belts for nonspecific low back pain actually work! Multicenter French trial enrolled 168 nsLBP pts - belt group had better wk 12, lower pain scores andless need for back pain medication. https://t.co/zgRclsoAR8 https://t.co/9HVwuE1YLz
Dr. John Cush @RheumNow( View Tweet )
In 2026 Abbvie granted 34 scholarships to students With Inflammatory Diseases. In the last 10 yrs, theyve granted $6 million to >350 students in the US for higher education. These awards up to $20,000 per student renewable up to 4 yrs. https://t.co/DFy5SukB6G https://t.co/9mVkrhL2lo
Dr. John Cush @RheumNow( View Tweet )

Risk of Venous Thromboembolism in Rheumatoid Arthritis

RA confers a 50–100% excess risk of venous thromboembolism (VTE) compared with the general population, with adjusted hazard/odds ratios ranging from 1.3–2.2 across large cohort studies (Vojinovic, Askling, Antovic; Rheumatology, 2026).

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Multiple chronic conditions (MCCs; AKA multimorbidity) is highly prevalent in AIRDs; complicates Rx & increases adverse outcomes & all-cause mortality. MMCs 86% in RA, 81.5% in SLE, w/ a notable patterns of cardiopulmonary and mental health disorders https://t.co/AOWCsEodXR https://t.co/NyAR0TUQkE
Dr. John Cush @RheumNow( View Tweet )

Joint Pain Prevalence is not Declining

A current report from the national NHIS survey shows that over half of US adults diagnosed with arthritis reported moderate to severe joint pain.

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JAMA: Review of Shoulder Pain

Shoulder pain affects 16% of adults annually and is the third most common musculoskeletal presentation in primary care. This new review reframes the diagnostic and therapeutic approach, moving away from pathoanatomic labels (rotator cuff tendinopathy, impingement, bursitis) toward the umbrella

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Efgartigimod Efficacy in Idiopathic Inflammatory Myopathy

Today Argenx announced the results of their Phase 3 "ALKIVIA" study; demonstrating efficacy and safety of subcutaneous efgartigimod for Idiopathic Inflammatory Myopathy (IIM, AKA inflammatory myositis).

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Can Effective Psoriasis Therapy Prevent Psoriatic Arthritis?

A review article assesses and integrates mechanistic, imaging, and clinical evidence to examine whether effective treatment of psoriasis may modify the future risk of psoriatic arthritis (PsA).

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Updated Guidance for Artificial Intelligence Use in Medical Publications JAMA has updated its guidance for the acceptable use of artificial intelligence (AI) in authoring a medical publication. Despite growing AI use, very low rates of disclosure of AI use have been reported. https://t.co/irid5koIjo
Dr. John Cush @RheumNow( View Tweet )

Doubting RS3PE (8.14.2026)

Dr. Jack Cush reviews the news and journal articles this week where RheumNow featured info on cancer, deadly viruses, AI rules, poetry and good moons rising.

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2026 PGY1 match for non–US citizen international medical graduates (IMGs) has reached a 5-year low; yet US health care relies heavily on non–US-born MDs. In US, there are 6300 Rheumatologists - 46.9% US born USMG; 5.4% US born IMG; 11.2% non-US born USMG; 36.5% non-US born IMG https://t.co/cwx5ugBaVE
Dr. John Cush @RheumNow( View Tweet )
Evaluating Inflammatory Joint Pain in Older Adults Lee, Levinson, and Makris have published an approach to evaluating inflammatory joint pain in older adults in JAMA Internal Medicine. While intended to be a practical guide for Primary Care Clinicians (PCCs), the tenets and https://t.co/TPKEOjkcKl
Dr. John Cush @RheumNow( View Tweet )

A Case of Sweet Syndrome

This overview appeared in JAMA Dermatology.

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Wealth and Where you Live Influences Outcomes Patients from wealthier European countries tend to start treatment with biologics earlier but also stop or switch treatment earlier. They also experience lower disease activity at treatment start than patients in middle- and https://t.co/MyzWRx580R
Dr. John Cush @RheumNow( View Tweet )
What's New in Lyme Disease JAMA has published an overview of new considerations on Lyme disease, focusing on Diagnostics, Vaccines, and Prevention. https://t.co/jG09wc6gI8 https://t.co/rQBW6RIz5U
Dr. John Cush @RheumNow( View Tweet )
"Be so good they can't ignore you." - Steve Martin https://t.co/lMRAY57rW9
Dr. John Cush @RheumNow( View Tweet )

2026 BSR Pain Guideline: What Rheumatologists Need to Know

The British Society for Rheumatology has issued its first guideline dedicated solely to pain in inflammatory arthritis (IA)—covering RA, PsA, axial SpA and JIA.

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Updated Guidance for Artificial Intelligence Use in Medical Publications

JAMA has updated its guidance for the acceptable use of artificial intelligence (AI) in authoring a medical publication. Despite growing AI use, very low rates of disclosure of AI use have been reported. This update provides specific information about what is permitted and not permitted, and

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From 1975 -2025, incidence of Kawasaki dz (KD) increased 16.1-fold in Japan, KD cases 15 032 and& 14 809 in 2023 & 2024, but during COVID #s dropped to 10 333 in 2022. KD #s rebounded after the COVID-19: Infants showed minimal changes, but kids 5-9 had the greatest increase https://t.co/j0BL2ZELXn
Dr. John Cush @RheumNow( View Tweet )
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