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General Rheumatology

Expert Perspective on Calcium Pyrophosphate Deposition Disease A current perspective article by Dr. Sara Tedeschi tackles many unresolved issues around CPPD diagnosis, classification, and management, including the lack of clinical trials or FDA approved treatments. https://t.co/zxJ9aQweNl
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Gout and its' associated comorbidities - treat gout and its' comorbidities to target https://t.co/U0dolcAGEc https://t.co/mGvYQrWx25
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Nerandomilast (Jascayd) has been approved in the European Union for adults with idiopathic pulmonary fibrosis (IPF) and progressive pulmonary fibrosis (PPF). The drug was approved for IPF & PPF by the FDA for US use in late 2025 https://t.co/scOuVb3aYy https://t.co/EcmpRhyWgu
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Chikungunya Club Meeting (7.24.2026)

Dr. Jack Cush reviews the news, journal reports from the past week on RheumNow.com.

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QD Clinic: Gout, Sepsis… or Both? Dr. Mrinalini Dey, London, discusses a complex case. https://t.co/UtncfZgZyL https://t.co/xVTA0LnPpN
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QD Clinic: Gout, Sepsis… or Both? Dr. Mrinalini Dey, London, discusses a complex case. https://t.co/UtncfZgZyL https://t.co/81SyzpWbcl
Dr. John Cush @RheumNow( View Tweet )

Evidence-Based Dietary Recommendations for Gout

Gout, historically referred to as the “disease of kings,” was once associated with a lifestyle of excess, including ready access to alcohol and rich meats once reserved for society’s highest ranks. Today, it is more appropriate to refer to gout as a “disease of commoners,” as it is

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Interferon-α as an Immunologic Driver of Sjögren's Disease

Using data from a Sjogren's registry, researchers have shown that IFNα drives Sjögren's disease, and
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Persistence of education and monitoring is crucial to optimal gout management

It is important that the misconceptions and myths held by the patient are discussed and dispelled and, most importantly, establish a clear understanding of “the plan” and the reason for initiating urate-lowering therapy (ULT).

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Gout patients are at greater risk for dementia, sleep apnea, septic arthritis and erectile dysfunction. For more gout content, follow our Gout: More than Flares campaign at https://t.co/lQoiFjubZJ, https://t.co/p4WQ1GCB68
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From 2015-2024, 148 inflam arthritis pts (43 SpA, 35 PsA, 50 RA) w/ a prior cancer were followed 58.1 mos. 24 (19%) had CA recurrence/progression. Post-CA exposure to b/ts-DMARDs did not incr. recurrence risk after adjusting for age & comorbidity burden. https://t.co/MHKIqwyjNN https://t.co/uhOdq1cCPW
Dr. John Cush @RheumNow( View Tweet )

Expert Perspective on Calcium Pyrophosphate Deposition Disease

A recent perspective by Tedeschi tackles many unresolved issues around CPPD diagnosis, classification, and management, including the lack of clinical trials or FDA approved treatments.

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ACP Position Paper on Dietary Supplements More than half of U.S. adults use dietary supplements, yet only a quarter use supplements recommended by a healthcare professional, and current law allows supplements to reach the market without a premarket safety evaluation, unlike https://t.co/gwLG4ElfCq
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Fibromyalgia: Diagnosis and Management

Fibromyalgia (FM) affects 4–6% of the U.S. population, with nearly a 2 fold female predominance. Nociplastic pain underlies the pathophysiology of FM. CNS hypersensitization to both painful and non-painful stimuli occurs with little or no tissue pathology. Framing FM as a disorder of CNS

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Metanalysis of 31 studies (14,548 pts) looked at infection in idiopathic inflamm myopathy (IIMs). Infection prevalence was 24%, primarily Respiratory tract. PJP, aspergillosis, H zoster most prevalent pathogens. Risk factors: older age, male, DM, HTN,MDA5+ (OR 3.41), rapidly https://t.co/GvOvAVRkRv
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Hip Replacement Advances Hip replacement surgery has been a major advance in the management of patients with hip damage and diminishing quality of life. While this review provides new information regarding a new type of hardware (end of article), lets begin with a general https://t.co/ZosOkoawiv
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Seronegative RA Disease Activity (7.17.2026)

Dr. Jack Cush reviews the news, journal articles and Gout features from this past week on RheumNow.com.

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ACR: Medicare Cuts for Physicians Highlight Need for Reform

ACR

The American College of Rheumatology (ACR) was disappointed that the proposed Medicare Physician Fee Schedule (MPFS) from the Centers for Medicare & Medicaid Services (CMS) once again included a serious cut to the conversion factor. The -1.68% cut—the sixth proposed cut in as many years—

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Genicular artery embolization for knee OA does not work in a 12-mos randomized sham-controlled trial of 58 pts. Pain scores improved equally in both groups https://t.co/7wwmzpTaNL https://t.co/8MsRXqKDo2
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Congratulations to Dr. Chandra Mohan and Univ. of Houston for receiving a $4 million NIH grant for a 10-year longitudinal study to identify the earliest biological triggers of autoimmune disease https://t.co/6kMcv9PD5r https://t.co/CsY8QAxrXR
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ACP Position Paper on Dietary Supplements

More than half of U.S. adults use dietary supplements, yet only a quarter use supplements recommended by a healthcare professional, and current law lets supplements reach the market with no premarket safety evaluation, unlike drugs or food additives. The paper notes that under DSHEA, dietary

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Gout in Minority Populations

Gout is the most common inflammatory arthritis, but its burden is not shared equally across populations. Recent research has revealed substantial racial and ethnic disparities in both who develops gout and the care patients receive. These differences reflect not only genetic susceptibility but

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Do we need Better Strategies to Prevent Osteoporotic Fractures? In a recent JAMA Viewpoints article, Dr. Susan Ott addresses several controversies in preventing osteoporosis (OP) related fractures. https://t.co/YpmyZGCsjz https://t.co/NUkJVcxBjc
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Guidelines to Spot Cancer in High Risk Dermatomyositis

MedPage Today

International guidelines can help identify dermatomyositis patients with a particularly high risk for cancer, according to a retrospective single-center U.S. study.

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New research shows synovial lining enriched in macrophages expressing SPP1 (encoding osteopontin) in proximity to fibroblasts and fibrin deposits. SPP1+ macrophages degrade fibrin & promote fibroblast proliferation that deposit collagen & does the damage, joint remodeling. A new https://t.co/yFxwAYFPPb
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