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Lovastatin Fails to Lower CRP and Activity in RA

Aug 04, 2020

Ridker and colleagues have shown that statins (3-hydroxy-3-methylglutaryl coenzyme-A (HMG Co-A) reductase inhibitors) are effective at treating hyperlipidaemia and lowering C-reactive protein levels; Aranaow and colleagues have shown that lovastatin, when given to rheumatoid arthritis (RA)

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#Texas we REALLY need to #WearAMaskSaveALife ... 6 patients of mine have tested positive for #COVID19 in the last week. #MedTwitter @rheum_covid @COVID19Tracking

Mohammad A. Ursani MD, RhMSUS DrMAUrsani ( View Tweet)

Jul 19, 2020
Registry of COVID CNS complications reports 125 pts; 77 (62%) w/ Cerbrovascular event (57 ischemic CVA), 9 intracerebral hemorrhage, 1 CNS vasculitis. 39 w/ AMS, 9 encephalopathy & 7 encephalitis.

Dr. John Cush RheumNow ( View Tweet)

Jul 17, 2020
Regeneron/Sanofi have reported their US phase 3 trial of Kevzara (sarilumab) 400 mg given to 194 critically ill COVID-19 patients, requiring mechanical ventilation, did not meet its primary and key secondary endpoints when added to supportive care.

Dr. John Cush RheumNow ( View Tweet)

Jul 17, 2020
Who you gonna call? Fauci that's who. Listen to Fauci LTF! LTF!

Dr. John Cush RheumNow ( View Tweet)

Jul 13, 2020
Reminders on Masking: 1. Everyone should wear masks; most who are infected dont know they are infx (asymptomatic); 2.

Dr. John Cush RheumNow ( View Tweet)

Jul 13, 2020
10 FALSE reasons for not wearing a mask - https://t.co/zOViN8n4Yw Please wear a mask out of concern and care for others !!

Dr. John Cush RheumNow ( View Tweet)

Jul 10, 2020
Great NY Times article on 30+ years of an adversarial friendship between Dr. Tony Fauci and AIDS activist Larry Kramer (who recently passed away). Keen that adversaries can still be on the same side, pushing for change differently https://t.co/lnfk6fXfF2

Dr. John Cush RheumNow ( View Tweet)

Jul 10, 2020
AHRQ estimates that 40-80% of information a patient is told during an office visit is forgotten immediately, and that almost half of the information a patient does retain is actually incorrect https://t.co/XeGx2YXsOQ

Dr. John Cush RheumNow ( View Tweet)

Jul 08, 2020
23 yoF with 1 mos digital ulcers, hair loss, sicca Sxs, dysphagia; No sclerodactyly but finger tips cyanotic w/ distal pitting scars, ischemic ulcers, periungual erythema & dilated nailfold capillaries (no hemorrhages). +tests for ANA, Ro52, Ro60 and Scl-70 Abs. How to treat?

Dr. John Cush RheumNow ( View Tweet)

Jul 08, 2020
Rheumatology Round-Up from #EULAR2020 w/ Drs. Kavanaugh & Cush.

Dr. John Cush RheumNow ( View Tweet)

Jul 07, 2020
CDC guidelines for Rx of Latent Tuberculosis; Preferred: A) 3 months of once-weekly INH plus rifapentine (3HP); B) 4 months of daily rifampin (4R); C) 3 months of daily INH plus rifampin (3HR) - Shorter, safer, effective with higher completion rates.

Dr. John Cush RheumNow ( View Tweet)

Jul 07, 2020
A msg from my nurse friend: “A blood clot from my pt yesterday. Covid lungs. I helped changed his code to DNR, talked to his son/ex wife/brother&sister to say goodbye. He asked if I would pray w/him. I prayed. He cried. Then I walked out & lost it.
Jul 06, 2020

ICYMI: Outcomes of Critically-Ill COVID Patients in NYC

Jul 06, 2020

Lancet has reported COVID outcomes from NewYork-Presbyterian hospitals in NYC during March 2020 showing high rates of hospitalization, ICU admission, mechanical ventilation and death. 

A prospective observational cohort study 2 2 NYC hospitals from March 2 to April 1, 2020, looking at

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I have entered more patients with #COVID19 in the @rheum_covid registry in the last 3 days than I have in the last 3 months. Come on Texas- we can do better! Wear your mask, watch your distance, and help each other stay healthy #July4th @RheumNow
Jul 03, 2020
Claims data study of nearly 3 million receiving influenza vaccination shows an increased risk of subsequent subdeltoid bursitis, but incredibly low with an attributable risk was 7.78 additional bursitis per 1 million vaccinated.https://t.co/qtzd8pWk4O

Dr. John Cush RheumNow ( View Tweet)

Jul 03, 2020
UK population study shows fibromyalgia pts have a higher risk of Self harm (HR 2.06; 1.60,2.65)), RA (HR 1.59) & OA, but not ank spondylitis.

Dr. John Cush RheumNow ( View Tweet)

Jul 02, 2020
66 critically ill & 13 non‐critically ill COVID‐19 were tested for multiple anti‐phospholipid (aPL)Abs. APL common (47%) in critically ill, may be transient (35‐39d post onset). Multiple medium/high levels aPLs may identify at risk for CVA or APS

Dr. John Cush RheumNow ( View Tweet)

Jul 01, 2020
According to the Agency for Healthcare Research & Quality, it is estimated that 40-80% of information a patient is told during an office visit is forgotten immediately, and that almost half of the information a patient does retain is actually incorrect https://

Dr. John Cush RheumNow ( View Tweet)

Jun 30, 2020
RECOVERY RCT, dexamethasone vs usual care in COVID19 ⬇️28d mortality in pts on O2 (21.5% vs 25%, NNT ~22) or IMV (29% vs 41%, NNT~8)... ?⬆️ for pts w/out O2 1. Preprint*️⃣ 2. No blinding, but hard outcome & meaningful benefit Will likely be adopted, kudos 🇬🇧 for a useful RCT!
Mike Putman EBRheum ( View Tweet)
Jun 27, 2020
35 pregnant women w/ baseline & postpartum MRI-SIJ. 27/35 (77%) had SI bone marrow edema postpartum, 60% met ASAS definition of +MRI. 6 and 12 mos after, 46% and 12% still showed BM edema.

Dr. John Cush RheumNow ( View Tweet)

Jun 23, 2020
The 5 states with the highest slope of case increasing, per million population, June 20th 1. Arizona (way out in front) 2. South Carolina 3. Florida 4. Texas 5. Oklahoma (pre-rally) https://t.co/M1PsBgmhJb
Eric Topol EricTopol ( View Tweet)
Jun 21, 2020
Congratulations to Christopher Buckley, Kennedy Professor of Translational Rheumatology at the University of Birmingham and Oxford, for being awarded the 2020 Carol Nachman prize for Rheumatology https://t.co/xis9RmsoCf

Dr. John Cush RheumNow ( View Tweet)

Jun 18, 2020
African-Americans with Ank Spondylitis have worse disease compared to whites. Study of 10,990 AS patients shows AA to have high frequency of anterior uveitis, hypertension, diabetes, depression, and heart disease and higher ESR and CRP levels.

Dr. John Cush RheumNow ( View Tweet)

Jun 17, 2020
Measures to address Rheumatology Workforce shortages: 1) increase Rheum training programs; 2) expand use/utilization of NP, PA,pharmacists; 3) Telemedicine expansion; and 4) measures to reduce physician burnout https://t.co/oCE8ZxBpVv

Dr. John Cush RheumNow ( View Tweet)

Jun 17, 2020
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