Neoplasia and Autoimmune Disease

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Malignancy rivals cardiovascular disease as a leading cause of death in patients with systemic autoimmune diseases. Chronic inflammation and immune dysregulation can drive oncogenesis, while antitumor immune responses can trigger autoimmune phenomena (paraneoplastic syndromes, checkpoint inhibitor-induced rheumatic disease).

Switch or Cycle - Upadacitinib vs Adalimumab in Refractory RA

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After the first tumour necrosis factor inhibitor (TNFi) failure, patients with active rheumatoid arthritis (RA) responded by switching to upadacitinib, compared to cycling to a second TNFi, adalimumab.

Follow the Money (4.23.2026)

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Dr. Jack Cush follows the money and all the news that fits the Rheumatology Gab for this past week. 

Twofold Mortality in SLE

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NSAIDs in Inflammatory Bowel Disease?

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At least some patients with inflammatory bowel disease (IBD) can safely use common drugs for musculoskeletal aches and pains, a large study of insurance claims data suggested, contradicting a widespread concern that these products can trigger IBD flares.

ACR Endorses New Training Model for Pediatric Subspecialties

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The American College of Rheumatology (ACR) welcomes the recent announcement from the American Board of Pediatrics (ABP) outlining new training models for pediatric subspecialties.

Rheumatology Salaries 2025

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Medscape has published its annual Physician Compensation report with physican salaries up roughly 3% and eight specialties earning more than $500,000 per annum. 

Aspirin Cardiovascular Prevention in Giant Cell Arteritis

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A retrospective target trial emulations has shown that low-dose aspirin (ASA) given with a giant cell arteritis (GCA) diagnosis is associated with a lower risk of major adverse cardiovascular events (MACE), but a higher risk of GI bleeding.

Weight-loss drugs may affect joints directly

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A new study from Aarhus University shows that the hormone GLP-1, which is mimicked in medication for diabetes and weight loss, is present in joint fluid. In the long term, this may open up new treatments for arthritis.

Prescribing Lessons (4.17.2026)

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Dr. Jack Cush reviews the news and journal articles from this past week on RheumNow.com.

Adjunctive Prednisolone for Kawasaki Disease

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An NEJM study has shown that glucocorticoids provide no added benefit when added to standard primary treatment in Kawasaki disease patients.

ACR Backs the Provider Reimbursement Stability Act

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The American College of Rheumatology (ACR) today thanked lawmakers in the U.S. House of Representatives for introducing the bipartisan Provider Reimbursement Stability Act of 2025 (H.R. 8163), legislation designed to stabilize Medicare payments for physicians and protect patient access to care.