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Low dose rituximab for retreatnent of RA. —6 month trial —RCT 1000 mg or 500 mg or 200 mg single dose. —there were more flares with low dose but less SI. — DAS 28 response was similar #EULAR2019
Dr. Dinesh Khanna sclerodermaUM ( View Tweet)
Exercise program 30 min 12w (combination of generalised upper limb and specific hand exercises) helps to improve pain, function, dexterity, QOL over time more so than controlled group #eular2019 @RheumNow
Alberta Hoi tuna0sashimi ( View Tweet)
MTX withdrawal in tofacitinib MR 11mg ORAL shift 1y study @week 24, MTX blindly withdrawal for pt achieved LDA (CDAI <=10) n>200 each arm no difference between arms consistent with anecdotal evidence of how pt can withdraw MTX in real life. #eular2019 @RheumNow
Alberta Hoi tuna0sashimi ( View Tweet)
Vagal nerve stimulation for management of RA. Effective in refractory RA #EULAR2019 https://t.co/petEUKty7v
Dr. Dinesh Khanna sclerodermaUM ( View Tweet)
Please please publish this so we can quote it for our patients RT @CreakyJoints: Reassuring news about hair loss and methotrexate: a #EULAR2019 study of around 100 #RA patients found there was minimal hair loss related to MTX therapy. https://t.co/vHis3KZhbz
Alberta Hoi tuna0sashimi ( View Tweet)
#eular2019 H2H abatacept vs adalimumab prev study “AMPLE” showed similar efficacy (single blinded RA <2y study). Now “Early AMPLE” study for seropositive RA with or without HLA shared epitope confirmed previous observation of superiority of ABA at 24w
Alberta Hoi tuna0sashimi ( View Tweet)
It is always an absolute privilege working with Iain
Looking forward to his stint as @eular_org President...his track record suggests there will be some innovations ahead!
@Racegbn @iiiglasgow @UofGMVLS @imidbio https://t.co/932Iz9kayV
Stefan Siebert StefanSiebert1 ( View Tweet)
EULAR HIGHLIGHTS. Ixekizumab beats adalimumab in PsA on combined end pt of skin + joints due to high skin response #EULAR2019 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
EULAR Highlights. 2 new JAKs presented more RA data. Upadacitinib and Filgotinib. Safety of JAKs in meta-analysis -no new safety signals. Tofacitinib use in Corrona = TNFI except slightly more shingles. 7yr Baricitinib data good - no VTE in LTE #EULAR2019 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
Eular highlights. RA guidelines still mostly like before - all MOA drugs ok after MTX and still taper if sustained remission. I think don't fully D/C all background Rx in most #EULAR2019 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
Eular highlights. Don't forget aerobic supervised exercise to be prescribed in Axial SpA #EULAR2019 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
Comparison of high and low iris acid levels in a large cohort of gout patients shows high SUA associated with more comorbidities and CKD, more colchicine & indocin use. #EULAR2019 SAT0435 https://t.co/FvUU4Q6Ky9
Dr. John Cush RheumNow ( View Tweet)
Dr. Peter Lipsky - 1 Million #Gout Patients & who cares for them. SAT0435 #EULAR2018 https://t.co/WfFR4tRf2p
Links:
Dr. John Cush RheumNow ( View Tweet)
A very productive Mentor Mentee meeting with the best mentors and best mentees @EMEUNET #EULAR19 #Madrid https://t.co/nLQkdnK0u3
EMEUNET EMEUNET ( View Tweet)
@drdavidliew @OrphaLung @TobyMMaher @RheumNow See @RheumILD! We love Ritux!
Isabelle Amigues, MD, MS, RhMSUS, human, mom etc isa75012 ( View Tweet)
Eular highlights? SSc trials near misses for efficacy. Abatacept v placebo in early diffuse scleroderma had begun primary outcome for skin but positive composite measure of response (CRISS) TCZ beg on skin but nearly significant; maybe less lung progression #EULAR2019 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
Eular highlights SLE Rx Belimumab in largest SLE RCT is safe. Ustikinumab decreases interferon in SLE- Eploratory results from + RCT. Maybe blood levels of hydroxychloroquine may reduce Retinopathy by decreasing dose if high and detect adherence if too low #EULAR2019 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
Eular highlights in scleroderma. Nintedanib + for SSc ILD. Positive correlations of combined response in SSc measure and PROs in RCT exploratory analysis of Lenabusum a cannabinoid receptor agonist, maybe riociguat helps Raynauds and digital ulcers #EULAR2019 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
Eular highlights Sjögren's syndrome. Maybe new Rx pathway of small early phase RCT with RSLV-132 via toll like receptor 8 acting on interferon - reducing fatigue. Too early to know. #EULAR2019 @RheumNow
Janet Pope Janetbirdope ( View Tweet)