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I worry about really long term use and atypical fractures Irwin, pretty serious consideration after 7 years of BP therapy. https://t.co/RUQeLbpZjm
Dr Philip Robinson philipcrobinson ( View Tweet)
@_connectedcare @LaurentGrange I am just curious to see their names but really challenging to remember them. https://t.co/TuKQNcfu5m
Alberta Hoi tuna0sashimi ( View Tweet)
Gout and associated comorbidities - Edward Roddy @KeeleUniversity #EULAR2019 https://t.co/KC3ITm0FKZ
Dr.Martínez MtzReuma ( View Tweet)
Multitarget therapy for #Lupus under development
👉🏻 Fenebrutinib @Roche
👉🏻 Evobrutinib @MerckHealthcare
👉🏻 Spleen Kinase Inhibitors @GileadSciences @RigelPharma
👉🏻 Encoding transcription factors @Celgene
👉🏻 JAK/Tyk Inhibitors @PfizerCongress @LillyRheumEU @bmsnews @GSK
#EULAR2019 https://t.co/CeUwIQaCx4
Juan Ovalles, MD, PhD DrJuanOvalles ( View Tweet)
Gout management in CKD & allopurinol in the renal function.. - Roddy @KeeleUniversity #EULAR2019 https://t.co/B9TP4jHb4k
Dr.Martínez MtzReuma ( View Tweet)
Links:
Dr Suleman Khan Rheumatologistt ( View Tweet)
Marc de Meulemeester presents finding of #gout survey of 1100 patients across Europe at #EULAR2019. Significant burden of disease: 10% of patients had lost their job/retired due to gout, ability to walk, sleep, mental health & sex lives affected. https://t.co/uAcoChIBhV
Arthritis Ireland Arthritisie ( View Tweet)
Ustekinumab, an IL-12 and IL-23 inhibitor, in patients with active systemic #lupus erythematosus - a between group difference of 29%. Article in @TheLancet https://t.co/kic3xAfHcE #EULAR2019 #LancetRheumatology https://t.co/Wizel4nnSk
Links:
The Lancet Rheumatology TheLancetRheum ( View Tweet)
Predictors of severe cranial ischemic complications in Giant cell arteritis. 20%GPC patients presented/developed severe vision manifestations and/or ischemic stroke.. age and jaw claudication predicted severe cranial ischemic complications ~ Alojzija Hocevar #eular2019 https://t.co/PSaRfD5kSa
Dr.Martínez MtzReuma ( View Tweet)
GIACTA update #eular2019
RT @drdavidliew: To recall, part 1 52 wks, TCZ vs placebo & wean prednisolone. By end 52 wks, defined themselves by their response categories: remission no treatment, remission on treatment, active on treatment. What happens when IL-6 inhibition stops?
Dr Irwin Lim _connectedcare ( View Tweet)
IL-17A and IL-17F are secreted by entheseal T cells, and both synergize with TNF to recruit IL-17+ T cells to sites of inflammation. Timely translational data for bimekizumab #EULAR2019 THU0013 from Dennis McGonagle’s Leeds group @RheumNow https://t.co/27DMCBj1VV
David Liew drdavidliew ( View Tweet)
#Comorditiy is common in #gout & distinct #clusters form. #allopurinol can be safely be used in #ckd at higher than historically suggested doses. Uncertainty remains around association between gout & #neurodegeneration. #EULAR2019 @GoutEducation @GoutandYou @PCSciences @elinlowri https://t.co/7z6ZkbnZRZ
Dr James Prior DrJamesPrior ( View Tweet)
Lots of interesting questions posed by Dr. Eckstein #EULAR2019 here’s the FDA draft guidelines on structural endpoints in DMOAd development: https://t.co/mAKpASXXDb https://t.co/xAncVGyZjn
Jamie Collins CollJamie ( View Tweet)
GM-CSF may be implicated in many pathways in GCA, and its genetic signature in fresh temporal arteries is markedly increased in GCA vs controls. The anti-GM-CSF mAbs for GCA - watch this space #EULAR2019 THU0008 by Maria Cid @RheumNow https://t.co/smStOBq17b
David Liew drdavidliew ( View Tweet)
Comorbidity is common in gout, is challenging in CKD, allopurinol can be safely dosed higher than historical, uncertainty about relationships between urate gout and neurodegeneration .. avoid <3mg/dl in long term.. Dr. Roddy UK @KeeleUniversity #EULAR2019 https://t.co/TvESMxHG6y
Dr.Martínez MtzReuma ( View Tweet)
We’re starting to get a better idea of rheumatic irAE phenotypic clusters, which is the first step to better understanding and treatment - onward to collect more data, to get better detail! Many congratulations @ramos_casals! #EULAR2019 THU0649 @RheumNow https://t.co/TBYqb70Hsp
David Liew drdavidliew ( View Tweet)
Updated treatment algorithm for various pathological subtypes of #Lupus Nephritis #EULAR2019 https://t.co/Uun2OQXJLl
Juan Ovalles, MD, PhD DrJuanOvalles ( View Tweet)
In hand OA, both structural and inflammatory features are associated with pain sensitization (PPT = pain pressure threshold) #EULAR2019 OP0417 from Diakonhjemmet in Oslo @RheumNow https://t.co/97GwGGhH6Z
David Liew drdavidliew ( View Tweet)
As we start to use MRI to treat nr-axSpA outside of the tertiary centers, we’ve got to ask - how good are the local readers compared to specialized ones? Caution and more community radiologist education required #EULAR2019 THU0359 from ASAS classification cohort @RheumNow https://t.co/7Qqp1z0chO
David Liew drdavidliew ( View Tweet)
Is GCA seasonality present in the Southern Hemisphere (summer starts in December)? Maybe it’s when our pathologists are feeling summer-generous... small numbers but nice work from @winkler_gemma #EULAR2019 THU0323 @RheumNow https://t.co/v9iT965BAM
David Liew drdavidliew ( View Tweet)