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Presenting Features of Early SLE

d Jack Cush, MD

What clinical features best identify early systemic lupus erythematosus (SLE) patients from mimics?  A multicenter, multinational study aimed to evaluate manifestations at disease onset and to compare early SLE manifestations to those of diseases mimicking SLE.

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Artificial Intelligence to Predict Rheumatoid Disease Activity

d Jack Cush, MD

A recent study in JAMA Network Open shows that artificial intelligence models can use electronic health record data to prognosticate future patient outcomes in rheumatoid arthritis (RA).

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Autoimmune Disease Clustering at ENDO 2019

d Jack Cush, MD

A twin registry database study was presented at the Endocrine Society's annual meeting (ENDO 2019) in New Orleans, showed that that having autoimmune disease significantly increases the risk of other autoimmune disorders and that autoimmune clustering was highest in Addison's disease and vit

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2019 Doximity report shows Rheumatologists are the 14th lowest paid of all medical specialties; but is amongst the lowest with a gender gap difference. check it out here https://t.co/j3YOybQ78n

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Murine BM–derived macrophages or human monocytes treated w/ tofacitinib or selective JAK1, JAK3 inhibitors. Both TOFA & JAK1i but not JAK3i effectively inhibited STAT1 phosphorylation & IFN gamma production, suggesting affects on macrophage function. https://t.co/qILxzCDrCH

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Boehringer Ingelheim announce s FDA and EMA regulatory submission for nintedanib in systemic sclerosis associated ILD https://t.co/BQz94Kg4Px

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The genetics of ANKYLOSING SPONDYLITIS. #RNL2019 - Dr. John Reveille https://t.co/wIszzNqU01
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Ascending aortic involvement - you should do genetic testing to r/o Marfans >> or Ehlers Danilo’s. Here’s how. #RNL2019 - Dr. Philip Seo https://t.co/ISqWuSSdR3
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Erdheim Chester dz as a mimic of vasculitis or IgG4 related disease. Pearls from #RNL2019 Dr. Philip Seo https://t.co/TPuLfwG5Ye
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In newly Dx GPA it’s ok to treat with steroids PLUS MTX or MMF or RTX. #RNL2019 Dr Carol Langford https://t.co/rihhR6x7u3
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#RNL2019 Dr Carol Langford discusses when to use RTX vs CTX in GPA https://t.co/w0vWVrf7JX
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Catastrophic antiphospholipid syndrome 500pts: Most had a precipitating factor (65%), half infections. Organ involvement - kidneys (73%), lungs (60%), brain (56%), heart (50%), skin (47%). LAC, IgG ACL & IgG β2-glycprot Abs were most common. Mortality=37% https://t.co/puLeBn0kBu

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After either RTX or CTX induction, 102 pts w/ ANCA-associated vasculitis were give maintenance w/ azathioprine plus belimumab or placebo. Belimumab did not reduce the flare rate (HR=1.07;) or relapse (HR=0.88) (NS) in these patients https://t.co/5EgdzRRXq8

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Lab testing for disorders of the ascending aorta. Dr Philip Seo. #RNL2019 https://t.co/asobKYdRma
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#RNL2019 Dr Carol Langford’s approach to Rx if GPA https://t.co/khy0h6sMA4
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Dr Phil Conaghan on the similarity between OA and PsA #RNL2019 https://t.co/za9YDAWilE
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Coal miners at higher risk for any arthritis (HR 2.3) and rheumatoid arthritis (HR 3.6) https://t.co/OKx9LiADWw

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serum soluble programmed cell death protein 1 (sPD-1)shown to correlate w/ BVAS activity in 59 pts w/ ANCA-associated vasculitis (AAV). sPD-1 was correlated with hemoglobin and serum albumin, but not ESR or CRP. https://t.co/GOShh8Kwb2

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Prevalence of gout continues to rise. NHANES data say prevalence of gout is 9.2 million inUS adults (2015-2016) (5.9 mill men; 3.3 mil women); hyperuricemia prevalences is 20.0%. ULT use in gout was 33% between 2007-2014. https://t.co/nDEJM7gTGA

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A review of OP Guidelines, published in Osteoporosis International, shows only 27 of the 70 guidelines patient Beliefs, Values or Perceptions. https://t.co/zGoX2aaxdP

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