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A Phase 2b study demonstrated the sustained efficacy of bimekizumab in pts with active AS to Week 48. Bimekizumab was generally well tolerated and no new or unexpected safety findings were identified #ACR19 @RheumNow
Dr. Antoni Chan synovialjoints ( View Tweet)
You can treat all of the Hep C all of the time - but you won’t get rid of related cryoglobulinaemic vasculitis >10% of the time.
SVR with DAA in HCV does not equal vasculitis cured!
(PS you can even get it de novo after SVR)
n=1019 Egypt, France, Italy
#ACR19 ABST0948 @RheumNow https://t.co/Lp3ZVMwTgj
David Liew drdavidliew ( View Tweet)
Here is result to save you looking it up in this highly refractory group
#ACR19 @rheumnow Abst0930 https://t.co/gYv7CZcMvL https://t.co/ToIavKEn4z
Dr Irwin Lim _connectedcare ( View Tweet)
Abstr# L14: data shows that in PsA you’re able to withdrawal MTX from the combo of tofacitinib+MTX without any loss of efficacy. Great news, because pts really like to minimize their meds when possible. #ACR19 @rheumnow https://t.co/3cDoTc1gWB
Dr. Paul Sufka psufka ( View Tweet)
@RheumNow #ACR2019 ABS899 Tart cherry concentrate had NO effect on serum urate, urine urate excretion or the frequency of gout flares over 28-day study period (p=0.76). However, those receiving allopurinol had significantly greater increases in urinary anthocyanins (p< 001) https://t.co/JJm9RCILoH
Olga Petryna DrPetryna ( View Tweet)
The amazing @GrantSchulert helps us begin to understand sJIA-associated lung disease #ACR19 @rheumnow #Abstr #ACRBest https://t.co/NGnjEYDBnL
Jonathan Hausmann MD hausmannMD ( View Tweet)
How would vagus nerve stimulation help Rheumatoid Arthritis??
#ACR19 @rheumnow Abst0930 https://t.co/NupaKJkXCL
Dr Irwin Lim _connectedcare ( View Tweet)
The C-VIEW open-label study found a significant reduction in the AAU flare rate in axSpA pts with a history of recurrent AAU during the first 48 wks of Certolizumab. Pts also experienced significant improvement in axSpA disease activity #ACR19 @RheumNow
Dr. Antoni Chan synovialjoints ( View Tweet)
@RheumNow #ACR19 ABS377 Stanford Univ retrosp stdy of pts w/ cardiac sarcoidosis supports use of TNFi in pts who failed cDMARs. Pts were able to reduce steroids dose w/no decline in LVEF in pts with preexisting CHF. larger, prospect studies needed
Olga Petryna DrPetryna ( View Tweet)
This is the device they used for the vagus nerve stimulation
#ACR19 @rheumnow Abst0930 https://t.co/XGKRjONTqf
Dr Irwin Lim _connectedcare ( View Tweet)
2 papers looking at TNFi on radiographic progression in Ankylosing Spondylitis. TNF inhibitor treatment slowed radiologic progression when compared to other therapies but covariables such as smoking and NSAIDs need to be considered #ACR19 @RheumNow
Dr. Antoni Chan synovialjoints ( View Tweet)
Filgotinib in RA (FINCH3); Another👍🏼 result for JAKi
How will we choose which JAKi to use in an increasing crowded space? Any thoughts?
#ACR19 @rheumnow Abst0927
Dr Irwin Lim _connectedcare ( View Tweet)
@rheumnow #ACR2019 ABS857 Stdy of 21 SLE pts received allogenic mesench stem cells IV ⬇️ inflamm through upregulation of periph tolerogenic CD1c+ DC, esp in LN. UC-MSCs express FLT3L that binds to FLT3 on CD1c+DCs to promote proliferat&inhibit apoptosis of tolerogenic CD1c+DCs
Olga Petryna DrPetryna ( View Tweet)
Over two years, there can be progression of facet joint ankylosis with most progression occurring in the thoracic spine. Whole spine low dose CT is a research tool to study progression of facet joint in radiographic axSpA patients. van Gaalen #ACR19 @rheumnow
Dr. Antoni Chan synovialjoints ( View Tweet)
#acr19 @rheumnow abstr#0849 #ACRbest
French database: Risk for CA in RA with biologics compared to traditional sDMARDS: n= 83,659
1. No ⬆️ risk solid malig
2. HR lymphoma 1.35. p value not sig
3. NO diff CA b/t biologic monoRx vs comb biologic + DMARD
*nonmelanomatous skin CA
k dao KDAO2011 ( View Tweet)
The discrepancy in diagnosis between rheumatologists and radiologists reflects the increasing insecurity of including only BME of SIJ as the major criterium for diagnosing axSpA. Structural changes are also important. Baraliakos #ACR19 @RheumNow #axialspondyloarthritis
Dr. Antoni Chan synovialjoints ( View Tweet)
Listening to @AngusWorthing talk about what @ACRheum's advocacy efforts are doing for their members. #ACR19 @rheumnow https://t.co/aLYPuh0Clr
Dr. Paul Sufka psufka ( View Tweet)
Semi-axial combined with standard semi-coronal scans in MRI protocols for sacroiliitis improved recognition of non-specific BME, which is in the posterior lower ilium in association with SIJ features, and in the anterior upper sacrum #ACR19 @RheumNow #axialspondyloarthritis
Dr. Antoni Chan synovialjoints ( View Tweet)
There is a strong association between smoking and MRI-SIJ inflammation over time in axSpA patients with type of work and level of education level irrespective of other socio-economic factors, systemic inflammation and treatment. Nikiphorou #ACR19 @RheumNow
Dr. Antoni Chan synovialjoints ( View Tweet)
Abstr#0848 @rheumnow #acr19 another study confirming that steroids dose correl to hospitalized infx: from Medicare database https://t.co/6SZqd0A8Xv
k dao KDAO2011 ( View Tweet)
