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Stopping Biologics Before Joint Surgery: Is Earlier Better?

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d RheumNow

Feb 14, 2019

Withholding intravenous abatacept (Orencia) for longer than a month before hip or knee arthroplasty among patients with rheumatoid arthritis (RA) did not lower the risk for postoperative infection, a retrospective claims-based analysis found.

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Mortality and Hospitalization with Pulmonary Hypertension in Systemic Sclerosis

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d Jack Cush, MD

Feb 14, 2019

PHAROS is a prospective cohort studying the natural history of pulmonary hypertension (PH) in systemic sclerosis (SSc). They have shown that risk factors for poor outcomes in this cohort included male sex, DLCO < 50%, exercise oxygen desaturation, and pericardial effusions.

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Dr Aryeh Fischer on MTX lung dz - it is rare. #RWCS2019 https://t.co/pIQvv0jEFW

Dr. John Cush RheumNow ( View Tweet)

Feb 15, 2019

Dr Aryeh Fischer on risk factors for ILD. #RWCS2019 https://t.co/a86BBgxEMm

Dr. John Cush RheumNow ( View Tweet)

Feb 15, 2019

Dr Aryeh Fischer on ILD increasing #RWCS2019 https://t.co/euvky7H3Bs

Dr. John Cush RheumNow ( View Tweet)

Feb 15, 2019

Good morning from #RWCS2019! Year in Review #1: HCQ doesn't work for hand OA, so stop using it! Jack Cush @RheumNow has talked about this multiple times on his podcast. I'd say the same for Sjogrens (see my podcast on JOQUER trial), but that's more controversial. https://t.co/fmb2bfVhg0

Mike Putman EBRheum ( View Tweet)

Feb 15, 2019

Analysis of a large Pediatric hospital database and 5679 SLE admissions shows that 12.4% had Pericardial Effusion (PCE) at entry. PCE was assoc w/ 2.5 higherrisk of In-hospital mortality(p 0.027) and 1.5 time more 30Day readmissions (p 0.001). https://t.co/XS6FEGfdH5

Links:

https://buff.ly/2tiby6Q

Dr. John Cush RheumNow ( View Tweet)

Feb 15, 2019

927 Lupus registry study shows that use of combined hormonal contraceptives was low (8%) and nearly half (55%) took place in the setting of possible contraindication such as aPL (52%), HTN (34%), migraine with aura (22%). More study and info is needed https://t.co/yTCKbRTp2m

Links:

https://buff.ly/2tlTclk

Dr. John Cush RheumNow ( View Tweet)

Feb 15, 2019

RCT of 559 patients undergoing hip replacement shows that postoperative use of paracetamol plus ibuprofen or ibuprofen alone significantly reduced morphine consumption. https://t.co/JbnkvBzibC

Links:

https://buff.ly/2S1ubWs

Dr. John Cush RheumNow ( View Tweet)

Feb 14, 2019

JBMR reports that women with single & multiple fractures (hip, spine, ribs) strongly negatively impacts the HRQL of older people over a prolonged period, and that they may not recover their prefracture QOL. https://t.co/1udPUiyCc0

Links:

https://buff.ly/2GppqVw

Dr. John Cush RheumNow ( View Tweet)

Feb 14, 2019

Small study of 25 pregnancies in RA compared those who continued biologics till conception vs those who stopped before conception. Continuing biologics till conception lead to a significantly shorter time to pregnancy. https://t.co/NjhMDbQVux

Links:

https://buff.ly/2RZ6aPL

Dr. John Cush RheumNow ( View Tweet)

Feb 14, 2019

Dr Anne Stevens at RWCS. Many dysregulated paths contribute to fibrosis in disease. #RWCS2019 https://t.co/dCXjoge0yL

Dr. John Cush RheumNow ( View Tweet)

Feb 13, 2019

Dr Anne Stevens at RWCS. Pathways to Fibrosis. #RWCS2019 https://t.co/gTYWWrxY81

Dr. John Cush RheumNow ( View Tweet)

Feb 13, 2019

Dr Paul Emery at RWCS. RA without xray erosions- 45% have ultrasound erosions #RWCS2019 https://t.co/MlOUaMTgfd

Dr. John Cush RheumNow ( View Tweet)

Feb 13, 2019

Dr Paul Emery at RWCS. #RWCS2019 https://t.co/MFqjLVzpDa

Dr. John Cush RheumNow ( View Tweet)

Feb 13, 2019

Dr Aretha Fischer on how to tx ILD. #RWCS2019 https://t.co/vZhX25NhFF

Dr. John Cush RheumNow ( View Tweet)

Feb 13, 2019

Dr Aretha Fischer on ILD. #RWCS2019 https://t.co/YAyXapxr8C

Dr. John Cush RheumNow ( View Tweet)

Feb 13, 2019

The Best Rheums go to the Best Meetings - RHEUMNOW LIVE - March 22-24 2019 Great Venue =Fort Worth. Short Lectures, interactive sessions, Q&A panels, TED (like) Talks, digital, streaming and much more. You dont want to miss this meeting! https://t.co/5TVg0Frsbf

Links:

https://buff.ly/2qX0Mlp

Dr. John Cush RheumNow ( View Tweet)

Feb 13, 2019

Genetic study using Mendelian randomization methods in a large UK biobank shows that whereas serum Uric acid has no association with eGFR level nor CKD risk, sUA does show a significant risk of #Gout. https://t.co/YRiVuOKof4

Links:

https://buff.ly/2W2kdHO

Dr. John Cush RheumNow ( View Tweet)

Feb 13, 2019

In a mouse model of Pso/SpA/IBD the administration of IL-23 was associated with specific microbiome changes that correlated with disease activity https://t.co/wWjVNkvOfz

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