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Florida Approves Import of Drugs from Canada Last Friday, the FDA approved Florida’s plan to import certain prescription drugs directly from Canada. Florida is the first time a state to undertake this pathway to save money. https://t.co/OoYew2zr5M https://t.co/UMds4m0WvC

Florida Approves Import of Drugs from Canada | RheumNow

QD Clinic - A Non-Textbook Patient Widespread pain and a swollen wrist https://t.co/OixGhsKHRQ https://t.co/lvZ0duYwxw

QD Clinic - A Non-Textbook Patient | RheumNow

Curcumin therapy for knee osteoarthritis Curcumin is widely used in traditional Chinese medicine to treat arthritis and is presumed to have analgesic and antiinflammatory effects that may benefit those with osteoarthritis, particularly KOA. https://t.co/0EmPrEZTce https://t.co/74uNQJ3a34

Curcumin therapy for knee osteoarthritis | RheumNow

Biomarker Predicts Survival in Autoimmune Lung Disease One major subgroup of patients with ILD arising from polymyositis/dermatomyositis (PM/DM) survived significantly longer when serum levels of interferon-λ3 were relatively low, researchers found. https://t.co/2nYPBbNfCh https://t.co/n2Llxb7tdx

Biomarker Predicts Survival in Autoimmune Lung Disease | RheumNow

Congratulations to Professor Paul Emery OBE on being named CBE: Commander of the Most Excellent Order of the British Empire for his research and advances in rheumatology. He is the Versus Arthritis Professor of Rheumatology, Leeds Institute https://t.co/27igYiQxna https://t.co/KcQk5LasfN

Colleagues celebrate New Year Honours

AutoAbs in poly/dermatomyositis - ANA+ 50% to 80%, but not helpful in Dx. Look for MSA Abs - espec antisynthetase ABs (anti-Jo-1), but also newer Abs: MDA-5, TIFF-1 gamma, NXP-2 (to be discussed #RNL24 Dr. Christopher-Stine) https://t.co/ZRlMPE48qX https://t.co/kxD1jw832C https://t.co/afC617tbmq

GNSC-001 gene therapy w/ a recombinant adeno-assoc. viral vector expressing IL-1Ra, to block IL-1. GNSC-001 now in a phase Ib, 50 pt, 10 center USA trial to assess its efficacy in Knee OA. Given as single injx in the affected joint; results in late 2024 https://t.co/jW9FHlGyC2 https://t.co/Dbv15Flqlv

https://t.co/jW9FHlGyC2

Global temporal trends in MSK disorders in women of childbearing age increasing in138 countries, 24 decreasing & 42 w. flat trends. In 2019, the prevalence was 354 million w/ India, with China, USA, Indonesia & Brazil highest w/ 51% of global prevalence https://t.co/8nn4lTtNU2 https://t.co/BdkR3aXsZO

Global, regional and national temporal trends in prevalence for musculoskeletal…

Full Read review of #PMR in Lancet: - Start @ 12·5–25mg prednisone qd - Remission in most but, relapses in 40–60% - Onset sudden; AM stiffness predominates; Shoulders>Pelvic ~50% have distal MSK Sxs - US: look for B/L sub-acromial/deltoid bursitis https://t.co/NwrbdMMdLU https://t.co/eRls0fLMJs

Polymyalgia rheumatica

JAMA: cutaneous hallmarks of dermatomyositis. Printable Patient education overview. https://t.co/S7MaAz6fX2 https://t.co/5ETcQRz8Fd

Dermatomyositis

Plantar Fasciitis study of 180 PF patients shows no clinically meaningful difference between pts treated with patient advice plus heel cup alone (PA) versus PA and lower limb exercise (PAX) versus PAX plus corticosteroid injection (PAXI) https://t.co/X5Q1MlmkzW https://t.co/NtbLQv6b2q

Does a corticosteroid injection plus exercise or exercise alone add to the effe…

Best of 2023: PMR: glad or bad tidings? “Life was turned upside down overnight” – PMR patient. https://t.co/l7jZei5Kfm https://t.co/Ct3qlHd34P

Best of 2023: PMR: glad or bad tidings? | RheumNow

Best of 2023: EULAR/ACR Guidance on Haemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome https://t.co/QQ2IEEMQVy https://t.co/M4NHkasFz6

Best of 2023: EULAR/ACR Guidance on Haemophagocytic Lymphohistiocytosis/Macroph…

Best of 2023: 2023 ACR/EULAR Criteria for Calcium Pyrophosphate Deposition Disease The prevalence of radiographic chondrocalcinosis is estimated to be 4% to ≥10% in older adults, but the prevalence of symptomatic CPPD disease is unknown. https://t.co/gsCtfHzn4Z https://t.co/lIaf36epZY

Best of 2023: 2023 ACR/EULAR Criteria for Calcium Pyrophosphate Deposition Dise…

Best of 2023: How Being a Patient Taught Me to Be a Better Doctor Since I can remember, I always wanted to be a doctor. My dad was a trauma surgeon and my mom a nurse. https://t.co/JE4QoJy4jp https://t.co/jrJoqRD30P

Best of 2023: How Being a Patient Taught Me to Be a Better Doctor | RheumNow

Best of 2023: LAVLI - A New Autoinflammatory Disorder NIH researchers have have described a novel autoinflammatory disorder called "Lyn kinase-associated vasculopathy and liver fibrosis" (LAVLI), based on a mutation in the LYN gene. https://t.co/5nzq6KvOpy https://t.co/Y2MCXkGck2

Best of 2023: LAVLI - A New Autoinflammatory Disorder | RheumNow

Does King Charles have Sausage Digits (dactylitis) or OA? https://t.co/HpOdaXAxff https://t.co/HpOdaXAxff https://t.co/IrjJcxUG9b

Metanalysis of Steroids in hosp community-acquired pneumonia (CAP). 18 studies, 4661 pts. Corticosteroids reduced mortality in more severe CAP(RR 0.62; 0.45 to 0.85), but not less severe CAP(RR 1.08). Steroids lower need for mech ventilation, ICU https://t.co/1QbuCZRXze https://t.co/16qiqIatJq

Corticosteroids in Community-Acquired Bacterial Pneumonia: a Systematic Review,…

Denosumab Reduces Type II Diabetes Risk. The British Medical Journal has published a matched cohort analysis demonstrating that adults receiving denosumab had a lower risk of NIDDM compared with those taking oral bisphosphonates for osteoporosis. https://t.co/vZALPMU8lI https://t.co/yGvDLHIp5y

Denosumab Reduces Type II Diabetes Risk | RheumNow

Bimekizumab in Hidradenitis Supprativa (HS) - results of 2 phase III BE HEARD I & II trials show Week 16 50% HS Responses to be 48% and 52% (vs PBO 29% and 32%). >75% maintained response out to wk 48; at wk 48, a 75% HS response seen in 55%. https://t.co/vAMPWV1gKi

AAD: Awaiting FDA decision in psoriasis, UCB touts 48-week data for bimekizumab…

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