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ICYMI: Outcomes of Critically-Ill COVID Patients in NYC
Lancet has reported COVID outcomes from NewYork-Presbyterian hospitals in NYC during March 2020 showing high rates of hospitalization, ICU admission, mechanical ventilation and death.
A prospective observational cohort study 2 2 NYC hospitals from March 2 to April 1, 2020, looking at laboratory-confirmed COVID-19 and were critically ill with acute hypoxaemic respiratory failure, and collected clinical, biomarker, and treatment data. The primary outcome was in-hospital death.
I have entered more patients with #COVID19 in the @rheum_covid registry in the last 3 days than I have in the last 3 months. Come on Texas- we can do better! Wear your mask, watch your distance, and help each other stay healthy #July4th @RheumNow
k dao KDAO2011 ( View Tweet)
Claims data study of nearly 3 million receiving influenza vaccination shows an increased risk of subsequent subdeltoid bursitis, but incredibly low with an attributable risk was 7.78 additional bursitis per 1 million vaccinated.https://t.co/qtzd8pWk4O
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Dr. John Cush RheumNow ( View Tweet)
UK population study shows fibromyalgia pts have a higher risk of Self harm (HR 2.06; 1.60,2.65)), RA (HR 1.59) & OA, but not ank spondylitis. Pain and depression are risk factors for self-harm & self harm is a key risk factor for suicide.https://t.co/vXmZKYq3Pe
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Dr. John Cush RheumNow ( View Tweet)
66 critically ill & 13 non‐critically ill COVID‐19 were tested for multiple anti‐phospholipid (aPL)Abs. APL common (47%) in critically ill, may be transient (35‐39d post onset). Multiple medium/high levels aPLs may identify at risk for CVA or APS
Dr. John Cush RheumNow ( View Tweet)
According to the Agency for Healthcare Research & Quality, it is estimated that 40-80% of information a patient is told during an office visit is forgotten immediately, and that almost half of the information a patient does retain is actually incorrect https://t.co/XeGx2YXsOQ
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Dr. John Cush RheumNow ( View Tweet)
RECOVERY RCT, dexamethasone vs usual care in COVID19
⬇️28d mortality in pts on O2 (21.5% vs 25%, NNT ~22) or IMV (29% vs 41%, NNT~8)... ?⬆️ for pts w/out O2
1. Preprint*️⃣
2. No blinding, but hard outcome & meaningful benefit
Will likely be adopted, kudos 🇬🇧 for a useful RCT! https://t.co/m5OAYMIvZy
Mike Putman EBRheum ( View Tweet)
35 pregnant women w/ baseline & postpartum MRI-SIJ. 27/35 (77%) had SI bone marrow edema postpartum, 60% met ASAS definition of +MRI. 6 and 12 mos after, 46% and 12% still showed BM edema. Findings assoc w/ short labor & no epidural https://t.co/mhX3W96zR3
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Dr. John Cush RheumNow ( View Tweet)
The 5 states with the highest slope of case increasing, per million population, June 20th
1. Arizona (way out in front)
2. South Carolina
3. Florida
4. Texas
5. Oklahoma (pre-rally) https://t.co/M1PsBgmhJb
Eric Topol EricTopol ( View Tweet)
Congratulations to Christopher Buckley, Kennedy Professor of Translational Rheumatology at the University of Birmingham and Oxford, for being awarded the 2020 Carol Nachman prize for Rheumatology https://t.co/xis9RmsoCf
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Dr. John Cush RheumNow ( View Tweet)
African-Americans with Ank Spondylitis have worse disease compared to whites. Study of 10,990 AS patients shows AA to have high frequency of anterior uveitis, hypertension, diabetes, depression, and heart disease and higher ESR and CRP levels. https://t.co/YyLqlM85sD
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Dr. John Cush RheumNow ( View Tweet)
Measures to address Rheumatology Workforce shortages: 1) increase Rheum training programs; 2) expand use/utilization of NP, PA,pharmacists; 3) Telemedicine expansion; and 4) measures to reduce physician burnout https://t.co/oCE8ZxBpVv
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Dr. John Cush RheumNow ( View Tweet)
MMWR reports that hospitalizations were 6 times higher and deaths were 12 times higher when the COVID patient presented with comorbidities - the most common being cardiovascular disease (32%), diabetes (30%), and chronic lung disease (18%) https://t.co/JPynBcJYfR https://t.co/kiBEIV38Sg
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Dr. John Cush RheumNow ( View Tweet)
#EULAR2020 #op0201 nationwide cohort study: higher incidence of dementia in SLE (3.9/1000pys) vs non-SLE ( 2.73/1000pys). HR 1.43. In SLE risk of Alzheimer’s 1.4x &risk of vascular dementia 1.6x Higher than non-SLE cohort. Further studies to identify mechanism needed @RheumNow
Olga Petryna DrPetryna ( View Tweet)
#EULAR2020 #op0148 real world European study of Mepolizumab in 142 pts w/EGPA shows significant improvement of general, ENT, pulm&neuro symptoms. Significant reduction in BVAS, 90%decrease of asthma attacks by 12 mo, decreased steroid use. 21.1%non-serious AEs @RheumNow https://t.co/fN4tKPvUaE
Olga Petryna DrPetryna ( View Tweet)
It is also important that I recognise the critical role of the @ACRheum and @eular_org to @rheum_covid as well as many other supporting organisations. Their contributions have been instrumental. We now also have corporate sponsors. Thank you all https://t.co/T15q5OwTLK
Dr Philip Robinson philipcrobinson ( View Tweet)
My brush with COVID- heart-breaking and inspirational. A story about Larry and Jessica. https://t.co/zZTmwcmRe0
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Dr. John Cush RheumNow ( View Tweet)
The first randomized clinical trial of convalescent plasma in #COVID19, reported by Li et al in JAMA suggests that high titer antibody against #SARSCoV2 may have antiviral efficacy https://t.co/6YIib2GXGX
JAMA JAMA_current ( View Tweet)
I'm really humbled by the amazing ongoing effort to collect cases for @rheum_covid. So many ppl are working tirelessly to help including the steering committee, patients & the pt board, contrib. rheums & the CASC. Please continue to contribute cases. Thank you 🙏 https://t.co/cK4FZXquMp
Dr Philip Robinson philipcrobinson ( View Tweet)
Best advice by Dr. R Landewe @EULAR2020 "Do NOT lose contact with your patients during the pandemic!" Many patients are fearful and will not reach out to their physicians; don't let them get lost in the shuffle. @rheumnow https://t.co/FAkEYexsGo
k dao KDAO2011 ( View Tweet)
