All News
Methotrexate and hepatic fibrosis: we must be doing something right
Methotrexate may be a rheumatologist’s best friend, but a key part of counselling any patient about its use has always been the risk of hepatotoxicity.
Read Article
Loved this session on: Preclinical Rheumatoid Arthritis- Can we stop RA? As a patient advocate living with RA, my providers have always ran tests on my microbiome. The findings have correlated with my disease flares, and was a big trigger overall. #ACR21 @ACRheum Thank you! https://t.co/6hm6hr85JS
Effie Koliopoulos RisingAboveRa ( View Tweet)
MRI Imaging in RA and SpA: Dr. Sheila Reyes ( @RHEUMarampa)
Dr. Sheila Reyes discusses abstracts #0468 and #0469, presented at the #ACR21 annual meeting.
https://t.co/MeVia60BNa https://t.co/WRgCifpioQ
Links:
Dr. John Cush RheumNow ( View Tweet)
Alcohol and MTX don't go along!
In a cohort of 1000+ early RA
Factors associated w/
1️⃣Nausea
Female OR 2
🍺 Alcohol OR 1.44
DAS28CRP OR 1.16
2️⃣Alopecia
Age OR 4.87
🍺 Alcohol OR 1.98
HAQ score OR 1.62
#Abst1444 #ACR21 @RheumNow https://t.co/zZG6aFR1SX
Aurelie Najm AurelieRheumo ( View Tweet)
Rheumatology Research Foundation Lecture: Learning lessons from @Google to harness #omics to better understand #RA
#ACR21 @RheumNow @RheumResearch https://t.co/NVAe2Rqo1O
Mrinalini Dey DrMiniDey ( View Tweet)
@NamrataRheum on outcomes in RA patients on RTX who get COVID-19. ⬆️hospitalisation, ICU, mech ventilation, but not mortality (in this cohort) Abstr#1445 #ACR21 @RheumNow https://t.co/8RcrzTdEb0
Richard Conway RichardPAConway ( View Tweet)
Yup, another large database shows more #hospitalizations with #RheumatoidArthritis with #rituximab but NOT higher mortality in matched analysis. Abst#1445 #ACR21 @RheumNow https://t.co/9XV8iX10sA
Janet Pope Janetbirdope ( View Tweet)
You can <but not as frequently> treat to target in #RheumatoidArthritis with virtual v in person visits. 45 docs in 18 practices comparing in person to virtual. In person wins but not by a large gap! Abst#1448 @dansolomon @RheumNow #ACR21 #ACRBest session today coming up https://t.co/8lcuMW0bwb
Janet Pope Janetbirdope ( View Tweet)
Does #baricitinib affect #fatigue in RA patients?
👉🏼Results from RA-BEAM and RA-BEACON
👉🏼4mg baricitinib significantly reduced fatigue, starting week 16, compared to placebo
👉🏼Effect independent of disease activity in active RA
Abs#1235 #ACR21 @RheumNow
https://t.co/0SKhUKJHd7 https://t.co/R76wc56u6I
Mrinalini Dey DrMiniDey ( View Tweet)
What predicts response to MTX in RA?
👉🏼DAS28-ESR
👉🏼RA duration
👉🏼Pt global assessment
👉🏼Swollen joint count
Abs#1227 #ACR21 @RheumNow
https://t.co/s942zvFiZ1
Mrinalini Dey DrMiniDey ( View Tweet)
Plenary Abs#1428 #ACR21
👉🏼Long-term #steroid use is common in RA incl in pts with high risk of #MACE
👉🏼30days of steroids ➡️ 15% increased odds of MACE
@RheumNow
https://t.co/fCM3m04ruS https://t.co/FWGmAatYu5
Mrinalini Dey DrMiniDey ( View Tweet)
26K Veterans data with RA #ACR21 plenary abst#1428
30 days on glucocorticoids - ⬆️15% odds of Major Adverse Cardiovascular events @RheumNow @BethIWallace https://t.co/BOram4o2rp
Bella Mehta bella_mehta ( View Tweet)
Role of GC on MACE in RA:
US database analysis 26000+pts
23% on GC >90d/6mo
Each 30days of GC dispensed ⏭15% increase in odds of MACE in the following 6month period!
Adjustment on several confounders but not disease activity.
#Abts1428 #ACR21 @RheumNow https://t.co/prdA7D5fLz https://t.co/F3wCcRAfuf
Aurelie Najm AurelieRheumo ( View Tweet)
Plenary Abs#1427 #ACR21
👉🏼#Statins assoc w/ reduced #CVD & all-cause mortality, outweighing
modest #T2DM risk increase in RA pts
👉🏼Reduction in all-cause mortality greater in RA than gen population
👉🏼Incr in T2DM risk is NOT greater in RA compared to gen population
@RheumNow https://t.co/WcF11B0C2s
Mrinalini Dey DrMiniDey ( View Tweet)
Statins in RA - plenary at #ACR21 UK Clinical
Practice Research Datalink 1989-2018 @RheumNow
Reduction in CVD risk, All cause mortality
INCREASE in Type 2 DM risk🧐 - need to make sure we look into it for RA patients!
Great work @UNMC_Rheum by Gulsen Ozen! https://t.co/YmTO0xcdjj
Bella Mehta bella_mehta ( View Tweet)
RA and CVD: take your statins!
Obs UK study
Statins ⬇️CVD HR=0.46
⬇️All cause death HR=0.68
w/ mild ⬆️ T2DM risk HR=1.33
(but not more than in general population)
⭐️NNT to prevent CVD 102
⭐️NNT to prevent death 46
⭐️NNH 127
#ACR21 #Abst1427 @RheumNow https://t.co/v6TinuklNv https://t.co/r0rD4jMmuh
Aurelie Najm AurelieRheumo ( View Tweet)
In a telemedicine world where you can't palpate joints virtually, how can we use pt self-joint counts well?
Patients & rheums might not always rate the same, but:
when RA pts say their joints are up or down,
rheum exam usually agrees👍
@earlyarthritis #ACR21 ABST1203 @RheumNow https://t.co/spUNTlMnDY
David Liew drdavidliew ( View Tweet)
#ACR21 Abst#1205- Discordance bw pt and MD global assessment in RA?
⭐️15% discordance (>30 mm difference in GA score)
⭐️⬆️ in LDA and mod disease, ⬇️ remission/high disease
⭐️♂️ sex, pain VAS, normal CRP, less TJC&SJC predictive
@Rheumnow https://t.co/N2qAaDiBE5
Links:
Eric Dein ericdeinmd ( View Tweet)
#ACR21 Abs#1210: Frequency of anterior atlanto-axial sublux in RA
⭐️Anterior atlanto-axial subluxation (aAAS) = 3+ mm, frequency = 25%
⭐️Radicular pain 20%, surgery 6%
▶️Longer disease duration, ⬆️ frequency of extra-articular manifestations
https://t.co/BfjCTlRJbt @Rheumnow https://t.co/xd9h5e9cDH
Links:
Eric Dein ericdeinmd ( View Tweet)
#clinicalpearls Cervical involvement in RA: is it underestimated? Cohort of 240pts: anterior atlantoaxial subluxation (aAAS) found in n=25 10.4 % patients, 1/3 with no neck pain! Joint restriction OR: 5.8 hx arthroplasty OR:3.6
#Abst1211 #ACR21 @RheumNow
https://t.co/KRkDP4ETMu https://t.co/soKTMPiMwy
Aurelie Najm AurelieRheumo ( View Tweet)
