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ACR20 - Day 3 Report
Here are my highlights from day three, Sunday, of the ACR 2020 Convergence.
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Prelim. results: Immunogenicity of adjuvanted #HerpesZoster subunit #vaccine in #RheumatoidArthritis patients taking #JAKinhibitors
- Most RA pts on JAKi have sufficient antibody response to HZ vaccine
- Acceptable safety profile
Abs#1997 #ACR20 @RheumNow
https://t.co/8HWAIwOATD
Mrinalini Dey DrMiniDey ( View Tweet)
Checkout this session live now for an update on RA treatment guidelines (last updated in 2015)! #ACR20 @RheumNow https://t.co/Y4Ax3E4OHb
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Poll results are in! 50% of those that responded note that they recommend breathing exercises, yoga, and increase dietary intake of turmeric and ginger to their RA patients! #ACR20 @RheumNow https://t.co/04vOUOzRtj
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Poll results are in! 48% of those that responded are not yet convinced of the benefits of omega-3 fish oil supplements in pts w/ RA! #ACR20 @RheumNow https://t.co/B6f8ecWj07
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
A large observat study showed no difference in risk of major CV events in RA pts that were newly started on either MTX or HCQ. A greater stroke risk but lower risk of MI & hospitalized HF was seen in MTX initiators. #Abst1993 #ACR20 @RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Dr Kaellmark reports on immunogenicity of adjuvant herpes zoster subunit vaccine in RA patients treated with JAKi. 40 RA patients and 20 controls. Satisfactory serological responses and tolerability seen. @rheumnow #ACR20 Abstr#1997 https://t.co/UlDe4NllU0
Richard Conway RichardPAConway ( View Tweet)
Abatacept in RA and ILD Patients: Dr Richard Conway (@RichardPAConway) #ACR20
https://t.co/e31VsnXFq5 https://t.co/sCrqLtXFFc
Links:
Dr. John Cush RheumNow ( View Tweet)
IA steroids for knee OA did NOT ^ X-ray progression to TKR vs IA Hyaluronic acid! Data from 2 cohorts, n=792 knees. Similar X-rays for single & multiple injections of either Rx. Not Randomized but helpful! Abstr#1652 @RheumNow #ACR20 @CRASCRRheum https://t.co/1yzr5QkIzV
Janet Pope Janetbirdope ( View Tweet)
New PT-CDAI showed agreement w/ MD(DO)-CDAI at id-ing active vs. controlled RA. Results suggest that PT-based swollen joints were more c/w physician assessments than PT tender joint counts. Useful for telemed! #ACR20 @RheumNow @Janetbirdope #ABS0483 https://t.co/tozp9qBRXT
Dr. Rachel Tate uptoTate ( View Tweet)
Dr Castillo-Bustamante presents a human otopathological study demonstrating RA involvement of ossicular joints of middle ear. Is there a functional effect on hearing? @rheumnow @bososhea #ACR20 Abstr#1759 https://t.co/iWlKs2KdOW
Richard Conway RichardPAConway ( View Tweet)
There is hope for RA fatigue - improvements seen in F sex, non-smokers, lack of depression, high baseline fatigue. Abst#1737 @RheumNow #ACR20. Interested in role of exercise in the study. Smoking is BIG cause of fatigue, must address with fatigued RA pts.
Eric Dein ejdein1 ( View Tweet)
Dr Winthrop reports on rates of influenza in RA in tofactinib clinical programme over 14-15 seasons. No significant differences in rates between tofa, ADA, MTX, and placebo. @rheumnow #ACR20 Abstr#L04 https://t.co/8RrG0I2Zwm
Richard Conway RichardPAConway ( View Tweet)
Kaleb Michauds study from the RA FORWARD registry shows, during the pandemic, significant medication changes (w/o MD consult) or appts. These observations show we were not prepared for this and that Rx suffered. #ACR20 Abstr#L05 https://t.co/vrDd0myGos https://t.co/JFUXItVdRQ
Dr. John Cush RheumNow ( View Tweet)
Dr Bergman reports on PROs in RCT of upadacitinib versus abatacept in bDMARD-IR RA patients. Greater improvement in PROs with upadacitinib especially in physical functioning, pain, and general health @rheumnow #ACR20 Abstr#1728 https://t.co/NWKrhYAfZn
Richard Conway RichardPAConway ( View Tweet)
Smartphone T2T management of RA & SLE is possible. With over 127,316 DAS28 & 42,593 SLEDAI assessments over 2 yrs. T2T was lowest in spring for both, correlating w/ holidays in China. #ACR20 Abstr#1018 https://t.co/bGJtSTDqzo https://t.co/34za6kokOp
Dr. John Cush RheumNow ( View Tweet)
SELECT-CHOICE on UPA vs ABA in RA in NEJM Oct 2020. How about PROs? UPA wins in phys fxn, pain, general health over ABA. Abst#1728 @RheumNow #ACR20. ABA better if a safety concern, but this is more evid to go for UPA
Eric Dein ejdein1 ( View Tweet)
#mskus findings in pt w/normal muscle volume(ABC) vs. w/sarcopenia(DEF).
This Japanese study showed US of VL muscle is useful in discriminating RA pts w & w/o sarcopenia. @RheumNow #ACR20 abs1537 https://t.co/Gv7V0eebEt
sheila RHEUMarampa ( View Tweet)
Accdg to this study, no association was found between IFN levels and cognitive function in SLE pts (even after considering factors like SLE dse duration)
Interesting! @RheumNow #ACR20 abs1788 @ZahiTouma https://t.co/F4j8H1CWJ9
sheila RHEUMarampa ( View Tweet)
High-intensity interval training (HIIT) benefits RA, & it looks more than just exercise-FM-CV health.
Changes in T cell activity, muscle oxidative metabolism after HIIT in sedentary RA pts n=12
Looking forward to seeing more in this area
@dukemedicine #ACR20 ABST1757 @RheumNow https://t.co/5gKheEUYJ6
David Liew drdavidliew ( View Tweet)
