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Higher Rates of Childlessness in Rheumatic Diseases
A large Finnish population study shows that several rheumatic diseases may impair reproduction and pregnancy outcomes, with significantly higher rates of childlessness or fewer children overall for women.
ACR Supports FY 2024 Budget
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ACR
The American College of Rheumatology (ACR) today expressed strong support for several key measures included in the Fiscal Year (FY) 2024 budget.
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Predicting Vasculitis Relapse
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MedPage Today
Scores on a patient-reported sino-nasal symptom questionnaire were associated with subsequent flares of one type of ANCA-associated vasculitis (AAV), researchers said.
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Window of Opportunity in Psoriatic Arthritis
A Dutch Early Psoriatic Arthritis cohort study shows that psoriatic arthritis (PsA) patients treated early (referred and diagnosed within in less than 12 weeks) had the best clinical outcomes.
Secondary Sjogren’s Ups Rheumatoid Arthritis Severity
A Swiss observational study has shown that rheumatoid arthritis (RA) patients with concomitant Sjögren’s disease (SjD) are more likely to have a severe RA phenotype, and be less responsive to treatment.
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Korean biologics registry study 526 Ank Spondylitis pts on TNFi > 1yr and tapered; 24.1% experienced flares. Predictors of flare included B27+, inflammatory LBP, psoriasis, SpA Fam Hx, DM, ≥50% TNFi tapering, Dz activity (ASDAS-CRP, BASFI) at tapering https://t.co/Pila2PBlpN https://t.co/WgF9UtfTiR
Dr. John Cush RheumNow ( View Tweet)
GEM: Your Clinic Desk needs to be where you can see your patients enter/walk/rise into the clinic. Also pts can see where you work. They learn you & you learn them in ways not gleaned from the exam room https://t.co/WfFqiuztW1
Dr. John Cush RheumNow ( View Tweet)
Window of Opportunity in Psoriatic Arthritis
A Dutch Early Psoriatic Arthritis cohort study shows that psoriatic arthritis (PsA) patients treated early (referred and diagnosed within in less than 12 weeks) had the best clinical outcomes.
https://t.co/mbftcq1dv8 https://t.co/VYNtByK9l0
Dr. John Cush RheumNow ( View Tweet)
Secondary Sjogren’s Ups Rheumatoid Arthritis Severity
A Swiss observational study has shown that RA patients with concomitant Sjögren’s disease (SjD) are more likely to have a severe RA phenotype, and be less responsive to treatment.
https://t.co/CZqLO2GSeM https://t.co/VyLKvUIfJ9
Dr. John Cush RheumNow ( View Tweet)
Obesiy (& Visceral abdominal fat) in Ankylosing Spondylitis is assoc w/ worse Dz activity, funct disability, & spinal mobility in study of 74 radiographic axSpA treated with bDMARDs. https://t.co/Z5e9cU62nS https://t.co/fD9lhj085B
Dr. John Cush RheumNow ( View Tweet)
High Mortality & complication rates seen in 53 #RA pts presenting w/ Periprosthetic joint infection - 54 PJI w/ avg age 65 yrs (32-88); mortality rate was 19%. Most common was Staphylococci (63%), w/ 20% w/ multiorganism infx & 6 C/S neg https://t.co/Syrm5qPKDQ https://t.co/bnMfMLmFJ7
Dr. John Cush RheumNow ( View Tweet)
BIOBADASER registry 1128 RA pts Rx w/ 1st ts/bDMARD, Among the 9.3% w. multimorbidity they noted higher DAS28 dz activity, but no differences in ts/bDMARD retention rates betw those w/ and without multimorbidity https://t.co/hZDpceuOFq https://t.co/pxSg6rKNNr
Dr. John Cush RheumNow ( View Tweet)
Korean claims study of #RA & pregnancy (& adverse preg outcomes (APO), shows MTX or LEF use w/in 3 mos of conception assoc w/ incr. in APOs (aOR 2.14-.68). In 5728 preg: 1152 APOs, HCQ most commonly used, DMARD use decreased during preg. https://t.co/fGRZS5ID4A https://t.co/LXaaVYcFsh
Dr. John Cush RheumNow ( View Tweet)
Post-COVID MDs spend more time on EHR mostly messaging w/ patients, with a 157% increase from prepandemic average. Each additional patient message was associated with a 2.32-min increase in EHR time per day (P < .001), mostly messaging https://t.co/yfPM3vTmRo https://t.co/XVwC50CH2C
Dr. John Cush RheumNow ( View Tweet)
Naysayers & Disrupters
Dr. Jack Cush reviews the news and journal reports from the past week - including a few contrary reports on infection, seropositivity and plasmapheresis.
https://t.co/tm3V8U7pv4 https://t.co/R8U04urRXg
Dr. John Cush RheumNow ( View Tweet)
Autoimmune dz pts have higher risk of macular degeneration. Cleveland Clinic study of 200K AMD vs controls, finds:
- SLE (RR 1.73)
- Scleroderma (1.65)
- Psoriasis (1.48)
- Vasculitis (1.48)
- RA (1.4)
- UC &CD (~1.42)
- Sarcoid (1.42) https://t.co/RKyriK1zPe https://t.co/9F7N1jHKxX
Dr. John Cush RheumNow ( View Tweet)
According to CDC, drug overdose deaths increased in 2022 - up to 107,941, ~1% higher than the nearly 107,000 overdose deaths in 2021. 70% of these are males. 2023 numbers are not yet final but appear to be stable... https://t.co/esTuwpp4YP https://t.co/Ap5XanllU9
Dr. John Cush RheumNow ( View Tweet)
CV Risk Early with Rheumatic Disease Diagnosis
A Finnish populaton study shows that the temporal relationship between cardiovascular (CV) comorbidities in rheumatic diseases (RMD) is seen early after the RMD diagnosis.
https://t.co/GlcVJdx7Ls https://t.co/VKp6Tgqkof
Dr. John Cush RheumNow ( View Tweet)
2023 EULAR Psoriatic Arthritis Recommendations
EULAR has updated its treatment recommendations— The updated guidance includes 7 overarching principles and 11 recommendations regarding treatment strategy and pharmacological therapies.
https://t.co/0hofxzGX9O https://t.co/FXOgEJ0P0F
Dr. John Cush RheumNow ( View Tweet)
Case of Delayed Rheum Diagnosis
The Washington Post recently published a case titled, "Medical Mysteries: A rolled ankle set this runner down a painful path", which tells the tale of how/why rheums are often not consulted or consulted too late.
https://t.co/Iigmf5jdDu https://t.co/mYYm5CEvtX
Dr. John Cush RheumNow ( View Tweet)
