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#EULAR2023 #POS1207 Promising therapy for dermatomyositis. Data from Stage One of Phase 2 RCT (N=18) showed Anti-IFN Beta mAb improved clinical, PROs, extra-muscular activity and reduced CK levels vs Placebo. No cases of HZV. One to watch out in the next few years @RheumNow https://t.co/Oh8sZlMzUt
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Factors related to having a flare of arthritis during COVID-19 include female gender, higher disease activity, no DMARD at time of vaccination. Stopping DMARDs need to be weighed up against risk of flares, Pedro Machado, COVID-19 #EULAR2023 @RheumNow https://t.co/3sd32tF2kW
Dr. Antoni Chan synovialjoints ( View Tweet)
The modern day poster tour #EULAR2023: the posters & speakers come to you, broadcast through a headset (it’s almost like a silent disco, in a hall with lots of background noise).
Definite innovation but at capacity, wish more people could tune in on their own devices @RheumNow https://t.co/sOXnYctsfN
David Liew drdavidliew ( View Tweet)
Debate @ #EULAR2023 @eular_org about clinically suspect arthralgia. Myth or just #rheumatoid #arthritis in the making? https://t.co/Kj4CeE3NtU
Janet Pope Janetbirdope ( View Tweet)
Did you know?
Painter Peter Paul Rubens had Rheumatoid Arthritis as demonstrated in swellings and deformities observed in this self-portrait
An image I often use in my teaching to student of clinical aspects of RA
#rheumatologyandart #teachingpearls
#EULAR23 @RheumNow https://t.co/xwDisTUHdy
Aurelie Najm AurelieRheumo ( View Tweet)
#EULAR2023 #POS1124 My newly diagnosed patients & their carers often expressed heightened anxiety with poor quality web info about #SLE. Thank you @LupusEurope for this wonderful effort 👏. Available in most European languages too @RheumNow https://t.co/cr5Ls117xM
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Study on folylPG synthétase (FPGS) activity and MTX-PG measured in sperm showed low bio active form of MTX-PG, low FPGS activity resulting in lower capacity to form MTX-PG, Perez-Garcia LF, Abst#OP0224 #EULAR2023 @RheumNow https://t.co/8sGQOBxn8r
Dr. Antoni Chan synovialjoints ( View Tweet)
A shame. Pts with #scleroderma are dying waiting for organ transplant- we should list and work them up for Tx earlier. PAH Pts May do worse @eular_org #EULAR2023 @RheumNow OP0241 https://t.co/8ZlHJmETGA
Janet Pope Janetbirdope ( View Tweet)
Herpes Zoster vaccination in RA patients treated with Upadacitinib and MTX showed a satisfactory response,
slight reduction in response compared to general population in both antibody and cell mediated responses Winthrop K, Abst#OP0225 #EULAR2023 @RheumNow https://t.co/wxwbOYsn5K
Dr. Antoni Chan synovialjoints ( View Tweet)
#EULAR2023 #POS0222 Post-hoc Analyses of Phase 3 RCT in Rituximab-treated ANCA vasculitis patients only (65% of total) showed more patients met Remission rate & with lower GC Toxicity vs Pred Taper + RTX at 52 weeks, consistent with Trial Main Results @RheumNow https://t.co/BmiujbhQI9
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Let le introduce you to ARTHUR 🤖
A very skilled robot who scans your hands and wrists in 15 mn 🤚
Amazing to see new #AI developments that will make our lifes’ easier!
#EULAR23 @ROPCA3 @JustSoren Stand M6
@RheumNow https://t.co/7PtR2CGqTt
Aurelie Najm AurelieRheumo ( View Tweet)
So what kind of changes do we see in ACPA+ arthralgia patients, in the 6 months prior to them developing inflamm arthritis?
- ACPA titre up, RF pos
- EMS, pain up
- ESR up
Good things to keep an eye on in pre-RA
Emery group POS1046 #EULAR2023 @RheumNow https://t.co/cSKPb5SbVH
David Liew drdavidliew ( View Tweet)
‘Where have all the rheumatoid nodules gone?’
(Fantastic poster title @MayoClinic)
Don’t get to see them much in clinic anymore. Almost surprised when I do
Smoking is down
Therapies are better
RA is changing
(a fact worth remembering!)
POS1066 #EULAR2023 @RheumNow https://t.co/VxDNusIjOa
David Liew drdavidliew ( View Tweet)
#EULAR2023 #POS1069 SLR & meta-analysis to inform EULAR Points to Consider which included 15 studies showed that targeted therapies were not associated with increased risk of cancer recurrence in patients with inflammatory arthritis AND a historyof cancer (85% had RA) @RheumNow https://t.co/uK2XHLjpj8
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
‘Clinically suspect arthralgias: fact or myth’ - a great debate topic #EULAR2023
First, the argument for. And we start with a reminder as to what we really mean by CSA
@RheumNow https://t.co/e1CdxKi69m
David Liew drdavidliew ( View Tweet)
“There was a time when a well-rounded physician had a good grounding in the humanities as well, and we lost that as more teaching time focused on understanding medical science and technology.” Brian Goldman
@RheumNow https://t.co/tfXHPRJXAo
Aurelie Najm AurelieRheumo ( View Tweet)
To treat or not? Clinically suspect arthralgia does affect QoL including function. Both premises of treating with a DMARD are valid. OverRx v missing the very early window of opportunity @RheumNow #EULAR2023 @eular_org https://t.co/86CVZ2IjEf
Janet Pope Janetbirdope ( View Tweet)
Use of antîmalarials in RA reduced the risk of bacterial infection in RA, smaller number of viral and fungal to study impact on systematic infections Bredemeier M, Abst#OP223 #EULAR2023 @RheumNow https://t.co/RXuFi3LdZC
Dr. Antoni Chan synovialjoints ( View Tweet)
Should we use #immunesuppression EARLY in #scleroderma to prevent #ILD? Answer from a study comparing Y vs N immune suppression- there was no difference in FVC decline. Maybe not a long enough study, ? Chanelling bias scleroderma #lung #disease OP0239 @RheumNow #EULAR2023
Janet Pope Janetbirdope ( View Tweet)
#EULAR2023 #POS1128 Promising new therapy on the block for #lupus nephritis. A single arm Phase 2a study showed Zetomipozomib, selective immunoproteosome-i + MMF showed about 2/3 pts met =>50% reduction in uPCR at WK24. No safety signal including low IgG or infection @RheumNow https://t.co/0A8cCW5GVV
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)