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An Alternative Pain Protocol Following Knee Replacement Surgery
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EurekAlert!
A study led by Vinod Dasa, MD, Professor of Orthopaedics at LSU Health New Orleans School of Medicine, reports that a novel surgical pain management strategy following total knee arthroplasty (TKA), or total knee replacement, provided pain relief without opioids.
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The Late Edition (2.24.2023)
Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com
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Periodontal Mucosal Breaks Trigger RA Disease Activity
Periodontal disease (PD) is more common in RA, especially those with anti-citrullinated protein antibodies (ACPAs). RA activity has been linked to the severity of PD and mucosal inflammation.
https://t.co/eTDNqlOHyp https://t.co/VZoeqJmsr0
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Dr. John Cush RheumNow ( View Tweet)
Metanalysis of 25 studies, betw 1985 - 2021, showed US average annual visits for RA=5.25 for US rheums (vs 3.3 ex-US) & 4.8 US non-rheums. SLE=3.24 & 12.3 for US non-Rheums. FM=1.8 for US rheums & 0.4 vs ex-US Rheums. Rheum Visits Decreased 1982 to 2019 https://t.co/WIXDXUCG60 https://t.co/s7W9gcd5dd
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Dr. John Cush RheumNow ( View Tweet)
5 Nordic register study of new b/tsDMARD starts in in PsA - 5659 ADA (56% biologic-naïve) & 4767 other b/tsDMARD (21% naïve) starts. ADA more often 1st line; newer b/tsDMARDsin biologic-experienced. 2nd line retention: ADA 65%, ABA 45%, Otez 43%. https://t.co/XKLiana6vB https://t.co/PotwYlYXto
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Dr. John Cush RheumNow ( View Tweet)
National study of 184,722 #RA pts (182 RISE sites) shows High % of socially deprived, high comorbidity, Medicaid- RA pts mainly in the south; <10% of Rheum practices cared for >50% of Medicaid RA pts. Moderate correlation betw comorbidity & Dz activity https://t.co/dsjH78cJqp https://t.co/U3l2m566d1
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Dr. John Cush RheumNow ( View Tweet)
Chest Pain & Fever
Lessons from the clinic, brought to you by https://t.co/4UQlqwujiR March 18 &19, 2023 - Dallas, TX
https://t.co/6iMT1Tt7KR https://t.co/owui66FMPJ
Dr. John Cush RheumNow ( View Tweet)
Comparing ACR21 vs EULAR22 RA Guidelines
https://t.co/dLtEaUBTKM https://t.co/Rang58z2N2
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Dr. John Cush RheumNow ( View Tweet)
Overview of Juvenile idiopathic arthritis (JIA) assoc uveitis (JIA-U) seen in 10–15% ofJIA pts, higher risk w/ ANA+, oligo-JIA, f& onset ≤6 yrs age. Rx options: topical steroids, MTX, ADA, INFLX, RTX and TCZ (review of TCZ in JIA-U) https://t.co/fqQ8ZhSLCM https://t.co/1GkUpCqJoE
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Dr. John Cush RheumNow ( View Tweet)
Survey of 300 Rheums, GI, Derms - concerns w/ new biosimilars
- majority say economics arent favorable to switch to biosimilar
- Yet majority "very to somewhat” comfortable w/ biosimilars
- US: Slow biosimilar uptake due to disappointing costs https://t.co/DOhrfELssY https://t.co/f2iy9igq5d
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Dr. John Cush RheumNow ( View Tweet)
Im not sure this was necessary but - a metanalysis of 10 RCTs w/ 847 OA patients shows colchicine use in osteoarthritis had no efficacy as far as pain reduction (vs control; SMD= 0.17) & no improvement in function (SMD, - 0.37) https://t.co/pDR0XO6vCg https://t.co/o8yYByBj8I
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Dr. John Cush RheumNow ( View Tweet)
Specific ACPAs and Autoantibodies Lead to RA-Associated ILD
https://t.co/AuTDGt8gYJ https://t.co/Q1rKdxkbLZ
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Dr. John Cush RheumNow ( View Tweet)
Vision Loss with ANCA-Associated Vasculitis
Shelley K. Dhillon, MD, presents her poster at RWCS 2023.
https://t.co/wE76hDJq4y https://t.co/pbuH4SBTSp
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Dr. John Cush RheumNow ( View Tweet)
Subscribe to the RheumNow podcast on your favorite podcast app to get automatic downloads of the latest content. Listen in the car, airplane, anywhere! Rate, review and subscribe!
https://t.co/3EENe1VFKl https://t.co/V0X5BAtDBq
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Dr. John Cush RheumNow ( View Tweet)
Comparing ACR21 vs EULAR22 RA Guidelines
https://t.co/sqYLrg9wC2 https://t.co/y3a8yDVQhP
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Dr. John Cush RheumNow ( View Tweet)
QD Clinic - Arthralgia, Raynaud's & Anemia
https://t.co/2H9EAZvP2s https://t.co/Bcerjoucjf
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Dr. John Cush RheumNow ( View Tweet)
A Singular Case of Plural Effusion
Shashank Suresh, MD, presents his poster at RWCS 2023.
https://t.co/xAR2WcK9MN https://t.co/KVGM9ri3cj
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Dr. John Cush RheumNow ( View Tweet)
Which Meds are Best for Acute Low Back Pain?
Acute low back pain (LBP) is a common cause of disability. An analysis in the Journal of Orthopaedic Research examined which non-opioid drugs are best for treating this condition.
https://t.co/StteWi87Y5 https://t.co/9CvYIqx5Cv
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Dr. John Cush RheumNow ( View Tweet)
New Drug Formulations – For Patients or Profits?
Wang et al in JAMA Network Research Letter, reviewed Medicaid expenditures on ADA, noted that the introduction of the citrate-free formulation cost an extra $4.4B to Medicaid from 2014-2021.
https://t.co/W1sst12GJK https://t.co/OYLkSHEQ2X
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Dr. John Cush RheumNow ( View Tweet)
32 men w/ B27+ #AS (Rx NSAIDs, BASDAI ~5.3) underwent exercise training (10d, 60min) w/ or w/o Pre-Rx w/ whole-body cryotherapy (WBC). WBC had significant drops in hsCRP, sP-Selectin, sVCAM-1, neopterin & signif decreases in BASDAI, BASFI, pain intensity https://t.co/8bmjTS4VOk https://t.co/ajrD8Z7C8v
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Dr. John Cush RheumNow ( View Tweet)