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Why do PROs matter? @DrLauraCoates reviewed this slide regarding the increased survival curve in end-stage cancer patients when we monitor PROs. @RheumNow #RNL2023 https://t.co/JfHNBKJGRl
Dr. Rachel Tate uptoTate ( View Tweet)
Dr.Robert Spiera approach to GCA #RNL2023 @RheumNow https://t.co/ublzYwBbIF
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Steroid sparing agents in GCA , what worked? By Dr.Robert Spiera #RNL2023 @RheumNow https://t.co/7Q9UYRSAhR
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
PMR by @anisha_dua @RheumNow #RNL2023 https://t.co/mHIBqqRUWh
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
How is a biosimilar approved?
Comparative effectiveness study for the reason that the medication was initial approved required, not for other indications
Jonathan Kay shows ex of ETN-ykro vs reference ETN in RA
Non-inferior in immunogenicity, safety, efficacy
@RheumNow #RNL2023 https://t.co/OOHie9Qr5t
Eric Dein ericdeinmd ( View Tweet)
Great #RNL2023 Plenary with "Miracle Larry" after 128 days in hospital for COVID-19, on 3-year anniversary of going into coma
"I am the expert on what this virus can do. I don't want the world to ever forget"
@RheumNow https://t.co/kTuDXDhTtQ
Eric Dein ericdeinmd ( View Tweet)
Tremendously emotional (and unfiltered) first person account of his fight with COVID-19 by Miracle Larry who thanked our Dr. Cush @RheumNow for his ingenuity in fighting COVID-19, thanking healthcare workers for all they do, and reminding us to be empathic.
#RNL2023 https://t.co/i0D7r8dR8n
Robert B Chao, MD doctorRBC ( View Tweet)
Was amazed at the tons of biosimilar TNF options @_connectedcare uses in Australia... coming soon to the US!
Jonathan Kay #RNL2022 shows the lists of biosimilar
May be w/in batch-to-batch variability, unintended drift, or deliberate process changes (evolution)
@RheumNow https://t.co/sfVQspxbyr
Eric Dein ericdeinmd ( View Tweet)
Jonathan Kay on #RNL2023:
Biosimilar is well-researched with cost savings
These savings should benefit the patients
Incentives for physicians as well in form of decreased prior auth burdens
@RheumNow
Eric Dein ericdeinmd ( View Tweet)
RBC MTX polyglutamate levels may be the “truth serum” for those pts stating they are taking their MTX but you question it. Dr. Kremer @RheumNow #RNL2023
Dr. Rachel Tate uptoTate ( View Tweet)
Larry Kelly celebrates life as he went on his “vent-cation” due to COVID19 three years ago today. #RNL2023 @RheumNow https://t.co/9sj3urqWD1
Dr. Rachel Tate uptoTate ( View Tweet)
Great #RNL22 Plenary with "Miracle Larry" after 128 days in hospital for COVID-19, on 3-year anniversary of going into coma
"I am the expert on what this virus can do. I don't want the world to ever forget"
@RheumNow https://t.co/6zgRwzOwz4
Eric Dein ericdeinmd ( View Tweet)
MTX is a prodrug!
MTX polyglutamate is true active ingredient
1/2 of MTX PG is 60 days, compared to only 6-8 horus for MTX
Steady state is not until 27.5 weeks!
Joel Kremer at #RNL2023 @RheumNow https://t.co/hodFZ2oi11
Eric Dein ericdeinmd ( View Tweet)
Do you stop MTX on patients on bDMARD?
MTX decrease anti-drug antibodies on patients on infliximab - increases drug duration.
Similar seen with new combination usage with pelogloticase
Joel Kremer MD
#RhuemNow @RheumNow https://t.co/8UrGZaFStA
Eric Dein ericdeinmd ( View Tweet)
“We valued sports, wit, and friendship. By all accounts that would make him a rich man but that was before COVID19.” @RheumNow #RNL2023 introduces “Miracle Larry”who battled 128 days hospitalized from the pandemic (and 62 years of knowing Cush!) https://t.co/91p5nPl0n9
Dr. Rachel Tate uptoTate ( View Tweet)
How do you wean MTX?
Consider every other week dosing as options - supported by 2 randomized studies from 1995 and 1999
Option to lower weekly dosing in patients that want to take less often
Joel Kremer #RNL2023 @RheumNow https://t.co/3GMdn3lLhy
Eric Dein ericdeinmd ( View Tweet)
MTX lung disease:
Presents at 6-12 months
Baseline CXR is key to know if lung infiltrates are new
#RNL2023 @RheumNow https://t.co/Whu4O1GLA9
Eric Dein ericdeinmd ( View Tweet)
Do and don’t around MTX , Dr.Kremer approach to MTX #RNL2023 @RheumNow https://t.co/dXLQ0epsp4
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
@Janetbirdope at #RNL2023
RA is not a disease of young
Incidence increasing in elderly population, not often offered the full range of medications due to co-morbidities, despite safety data
Higher DAS, seroneg
Co-morbidities decrease outcomes
@RheumNow
Eric Dein ericdeinmd ( View Tweet)
Myths of RA by Dr. Janet Pope
- RA development should have ACPA years before?
- there is a significant minority of early RA patients who are seronegative!
@RheumNow #RNL2023 https://t.co/pnOxTkfW0l
Robert B Chao, MD doctorRBC ( View Tweet)