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Low dose #glucocorticoids in rheumatic diseases can lower bone mass and increase # even 2.5 mg #prednisone. The change in #BMD was more predictive of fracture not absolute BMD. L01 #ACR22 #ACRBest @RheumNow https://t.co/MbTk0L4DoK
Janet Pope Janetbirdope ( View Tweet)
Mortality in patients with SpA
Abstract #0569 #ACR22 @RheumNow
✏️systematic review/meta-analysis of 19 studies
✋No increased mortality in patients with PsA compared to gen. pop.
🦠Infection, 🫀CV, and 🫁 pulm. specific mortality sig. higher in PsA patients
Catherine Sims, MD DrCassySims ( View Tweet)
How do we know what PMR is all about?
Imaging has helped enormously, and every step of the way, imaging has got better and better. Specific findings which reveal the culpable pathology.
@drceowen #ACR22 @RheumNow https://t.co/4OOOk0F3jW
David Liew drdavidliew ( View Tweet)
NSAIDs and CV risk in Inflammatory Arthritis
Dr. Richard Conway discusses abstract 1207, being presented #ACR22 meeting.
https://t.co/CjU2YbA3tk https://t.co/bHE4xw2IRF
Links:
Dr. John Cush RheumNow ( View Tweet)
#ACR2022 L07: Telitacicept - anti-BlyS and APRIL in SLE
335 pts P3 52 wk study TEL 160 mg SQ q7d vs PBO
83% SRI4 response in TEL vs 38% PBO (p<0.001)
As early as w4, sustained to w52
Most common AEs: URIs, decr IgG/IgM, injxn site rxn, UTI
@RheumNow #ACRBest https://t.co/UpEwEaonDO
Eric Dein ericdeinmd ( View Tweet)
Khanna et al Transdermal NaHCO₃ in gout flare. N=98. Response rate D7 95% vs 79% (p=0.01). Lower rescue med, 6% vs 20%. @RheumNow #ACR22 Abstr#1787 https://t.co/DWtlvjzBHw https://t.co/DOk993gCwz
Richard Conway RichardPAConway ( View Tweet)
Joy et al. Disease activity rather than steroid use increases risk of diabetes in RA in BeST study over 10 years. @RheumNow #ACR22 Abstr#1987 https://t.co/VT2eb3Q4m9 https://t.co/kquZ70o9bU
Richard Conway RichardPAConway ( View Tweet)
L08 #ACR22 TIX/CIL (Evusheld) in Rheum Pts
157 pts, f/u 154 days
24 breakthrough COVID ifns (15%)
2 pts required hospitalization, rest had mild-mod symptoms
No SAEs (CVD)
@RheumNow
Eric Dein ericdeinmd ( View Tweet)
#ACR22 Best in PsA and SpA - new Rxs, unraveling responses to Rx by sex/gender. X-ray inhibition w SpA drugs is a reality. Nice peeps working in these areas @RheumNow @ACRheum https://t.co/8VfdyyHPZi
Janet Pope Janetbirdope ( View Tweet)
Here's the 1 year model #ACR22 @RheumNow https://t.co/VhEuJMMyIt
Richard Conway RichardPAConway ( View Tweet)
Eder et al. New PRESTO prediction model for PsA development in PsO. 1 year and 5 year models presented @RheumNow #ACR22 Abstr#1612 https://t.co/xMMVaIGnN5 https://t.co/RlJ3ZlEeDE
Richard Conway RichardPAConway ( View Tweet)
Krijbolder et al. TREAT EARLIER DBRCT. MTX vs PBO for pre-RA. Treat 1 year, stop, and follow 1 year. No difference in RA development. Delay in ACPA+ or high risk. Sustained benefit in MTX group on pain, EMS, function, MRI. @RheumNow #ACR22 Abstr#1603 https://t.co/M2qQfgrhC1 https://t.co/UUeknTLx0K
Richard Conway RichardPAConway ( View Tweet)
Yazici et al. RCT of IA Lorecivivint for moderate/severe knee OA. CLK/DYRK inhibitor. No effect seen. @RheumNow #ACR22 Abstr#1899 https://t.co/XGQrMmNnSR https://t.co/rSJrT6Hms6
Richard Conway RichardPAConway ( View Tweet)
Bihlet et al. Anti-histamines may reduce structural progression of knee OA. Post-hoc analysis of 2 trials @RheumNow #ACR22 Abstr#1893 https://t.co/RrrelHDz75 https://t.co/Sf7RpjjAaN
Richard Conway RichardPAConway ( View Tweet)
Post-hoc analysis of SELECT-COMPARE showing decreased residual pain at week 12 but not week 26 cf. ADA, regardless of residual inflammation. Does this just reflect differing onset of action?
@RheumNow ABST0297 #ACR22
https://t.co/9WyZAN3B16 https://t.co/fAC1bLw9EB
Julian Segan JulianSegan ( View Tweet)
Shanahan et al. RCT of Genicular nerve block for knee OA. It works but temporary, with loss of effect by week 12. @RheumNow #ACR22 Abstr#1892 https://t.co/VySjBGrVeR https://t.co/JNKQeOVB6z
Richard Conway RichardPAConway ( View Tweet)
In a prospective cohort where MTX was withheld for 1 week post COVID vaccine, antibodies higher than other DMARDs which were continued (mostly RTX/MMF).
Good to see more direct data rather than having to extrapolate from flu.
@RheumNow ABST0913 #ACR22
https://t.co/YphKywNJfA
Julian Segan JulianSegan ( View Tweet)
Please find our Day 2 #ACR22 Daily Recap Video by @RheumNow Faculty
https://t.co/f3BbKkgzRp
@Janetbirdope @synovialjoints @doctorRBC @bella_mehta @AkhilSoodMD @RHEUMarampa @DrCassySims https://t.co/VZM53cUyWL
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Ho et al. Consistent colchicine use assoc reduction in MACE in patients with gout and pre-existing CVD. @RheumNow #ACR22 Abstr#1815 https://t.co/tXwa2FrSrp https://t.co/8TKl4z7iaH
Richard Conway RichardPAConway ( View Tweet)
Kastrati et al. Case series immune apheresis in IIM. 24 patients. Reduced CK in 21/24, 971 to 347. Reduced steroid 25%, median 12.5mg reduction @RheumNow #ACR22 Abstr#1882 https://t.co/UUlm4xEX61 https://t.co/bS2IA9OKnH
Richard Conway RichardPAConway ( View Tweet)