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✅ #EULAR2022 positive Phase 2 results for #deucravacitinib (TYK2 inhibitor) in systemic #Lupus with SRI(4) at 32W:
- DEU 3mg BID: 58.2% (p=0.0006)
- DEU 6mg BID: 49.5% (p=0.021)
- DEU 12mg QD: higher (but NS)
vs Placebo 34.4%
+ secondary endpoints.
https://t.co/QCWqW97tre
Laurent ARNAUD Lupusreference ( View Tweet)
#Cytokine #StormHour 🌀🌪️
#EULAR2022
#Great session by Dr.Peter Nigrovic🔥
❓Why sJIA/AOSD often accompanied by MAS❓⚡️
#Always wondered about this!🤔
✅Multiple mechanisms at play
✅Whats New➡️IFN gamma switch
✅mTORC1 is the NEW PIECE in the puzzle of sJIA/AOSD/MAS!🧩🧩 https://t.co/xLzCABunMb
debaditya_roy debaditya_roy ( View Tweet)
#EULAR2022 quote of the day. I was going to go to the fatigue session @eular_org but I was too tired and burnt out! @RheumNow
Janet Pope Janetbirdope ( View Tweet)
Subcutaneous #methotrexate in #rheumatoidarthritis is safer and better tolerated with better continuation rates than oral #MTX
#eular2022 https://t.co/cjmKntsEMe
Volker Bahr VolkerBahr ( View Tweet)
#Lovely slide when deep into the maze of AOSD!🌎🔍❓
#EULAR2022
⚡️Identify level of disease activity
⚡️Systemic/Articular?
⚡️Close monitoring
⚡️Identify non-responders early!
⏲️"DAVID" Project ongoing- validation of EULAR Disease Activity Score in AOSD!
Exciting times ahead!🔥 https://t.co/fuPPj4lEhs
debaditya_roy debaditya_roy ( View Tweet)
I also wonder about the significance of Ro52. Some of the commonly observed features like gastrointestinal dysmotility are not captured. https://t.co/UPljYf65vH
Alberta Hoi alberta_hoi ( View Tweet)
#EULAR2022
How to Manage (HOT): Lupus Nephritis
Voclosporin is the new CNI
long term reno-ischemic effects need to be looked at https://t.co/8RqayemaRu
EnvisionRheumat ERheumat ( View Tweet)
#EULAR2022
WIN session
Sarcoidosis – an update for rheumatologists
Clinical Approach https://t.co/AYOEDsnDZ6
EnvisionRheumat ERheumat ( View Tweet)
#EULAR2022 COVID orals
OP0172
Swedish COVID19-Reuma registry with n=414 ARD + 61 controls
RTX n=145, ABA n=21
In MVA, use of RTX, ABA were a/w lower Ab response. We've known this about RTX; growing data for ABA as well? https://t.co/Es9bA54m8E
Rheum Cat rheum_cat ( View Tweet)
Excited to share our recent work "IPAF: What the Rheumatologist Needs to Know."
@jeffsparks @UnaMakris @DrDavidKarp @UTSW_LungLadies @UTSWRheum https://t.co/O0BsrRyHx8 https://t.co/R3lQMGFgUb
Elena Joerns EJoerns ( View Tweet)
🔥Hot off the press🔥
🆕Our Comments on various GC protocols in @IJRheum
The changing paradigm of glucocorticoid therapy in antineutrophil cytoplasmic antibody-associated vasculitis
https://t.co/4BjfkvPVAY https://t.co/gMXg7qQJWY
Kunal Chandwar kunalchandwar ( View Tweet)
do we need another IL17a inhibitor? https://t.co/yf8cFNruzU
Peter Nash drpnash ( View Tweet)
"Implementation (of guidelines) is key but remains the weakest part of the process" Dr. @DanielAletaha #EULAR2022 @RheumNow https://t.co/9ULIAA7dvg
Dr. Rachel Tate uptoTate ( View Tweet)
Easy clinical tool for predicting lymphoma development at the time of #Sjogrens syndrome #EULAR2022 https://t.co/tQ6B0iVRnb
Christian Ammitzbøll RheumTweeter ( View Tweet)
Dr Buch. ORAL Surveillance. MACE, VTE, Malignancy all more common in those with high (>20%) baseline CV risk or history CAD. HRs 1-2 for most but for VTE and high baseline CV risk, HR 6-11! @RheumNow #EULAR2022 POS0237 https://t.co/9DI4KotyOp
Richard Conway RichardPAConway ( View Tweet)
Dr Elena Nikiphorou explaining how the Western diet can bring on and worsen inflammation joint disease symptoms. We should look to include more Omega 3 than Omega 6 in our diets #EULAR2022
PB https://t.co/nIKOSDPURU
ARD & RMD Open ARD_BMJ ( View Tweet)
A very comprehensive overview of progress in the understanding of #IIM pathogenetic mechanisms outlining the role of
👉 Type 1 INF pathway
👉 Vasculopathy
👉 NETs
👉 Mitochondrial Dysfunction
#EULAR2022
Dr. Lisa Rider https://t.co/BXbXlYTHYM
Ashima Makol MD AshimaMakol ( View Tweet)
van Dijk et al. MTP squeeze positivity is caused by both MTP synovitis (OR 3.2 (1.4–7.2) and intermetatarsal bursitis (OR 3.9 (1.7–8.8)). If + MTP squeeze - 10% synovitis, 15% IMB and 13% both @RheumNow #EULAR2022 OP0290 https://t.co/eVSU4i8gBK
Links:
Richard Conway RichardPAConway ( View Tweet)
Robert Landewe isn't lying down.
"I am chatting to my artificial intelligence doctor in the United States. I am asking him why I had a headache in the last talk"
He worries telehealth reverts to box checking, & we're not ready to drop thinking from medicine #EULAR2022 @RheumNow https://t.co/ApBS4T4Wpc
David Liew drdavidliew ( View Tweet)
CAR-T cell treatment of refractory systemic #lupus
Biological results
#SLE
#EULAR2022
>CR https://t.co/JK4lsWcn2c
ARD & RMD Open ARD_BMJ ( View Tweet)