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Difficult to treat RA? #EULAR2022
1) Active/progressive disease, unable to taper steroids, radiographic progressive, decreased QoL
2) Failure of medications (2+ b/tsDMARD after csDMARD)
3) Physician/patient perception
- Fatigue: not part of definition
~5-20% pts
@Rheumnow https://t.co/i5sfwoF2Gs
Eric Dein ericdeinmd ( View Tweet)
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When will this madness stop!? TNFi to treat OA (yet again). Adalimumab for "inflammatory" knee OA. And again it doesn't work. @RheumNow #EULAR2022 OP0229 https://t.co/htwyLTYwG4
Links:
Richard Conway RichardPAConway ( View Tweet)
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#POS0787 #EULAR2022 More data to support the association of Anti-Ribosomal P ab with Depression + Cognitive Dysfunction using functional MRI in #lupus. To screen for neuropsychiatric in ab+ patients @RheumNow https://t.co/9JQDImrHAt
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
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✅ #EULAR2022 positive Phase 2 results for #deucravacitinib (TYK2 inhibitor) in systemic #Lupus with SRI(4) at 32W:
- DEU 3mg BID: 58.2% (p=0.0006)
- DEU 6mg BID: 49.5% (p=0.021)
- DEU 12mg QD: higher (but NS)
vs Placebo 34.4%
+ secondary endpoints.
https://t.co/QCWqW97tre
Laurent ARNAUD Lupusreference ( View Tweet)
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#Cytokine #StormHour 🌀🌪️
#EULAR2022
#Great session by Dr.Peter Nigrovic🔥
❓Why sJIA/AOSD often accompanied by MAS❓⚡️
#Always wondered about this!🤔
✅Multiple mechanisms at play
✅Whats New➡️IFN gamma switch
✅mTORC1 is the NEW PIECE in the puzzle of sJIA/AOSD/MAS!🧩🧩 https://t.co/xLzCABunMb
debaditya_roy debaditya_roy ( View Tweet)
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#EULAR2022 quote of the day. I was going to go to the fatigue session @eular_org but I was too tired and burnt out! @RheumNow
Janet Pope Janetbirdope ( View Tweet)
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Subcutaneous #methotrexate in #rheumatoidarthritis is safer and better tolerated with better continuation rates than oral #MTX
#eular2022 https://t.co/cjmKntsEMe
Volker Bahr VolkerBahr ( View Tweet)
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#Lovely slide when deep into the maze of AOSD!🌎🔍❓
#EULAR2022
⚡️Identify level of disease activity
⚡️Systemic/Articular?
⚡️Close monitoring
⚡️Identify non-responders early!
⏲️"DAVID" Project ongoing- validation of EULAR Disease Activity Score in AOSD!
Exciting times ahead!🔥 https://t.co/fuPPj4lEhs
debaditya_roy debaditya_roy ( View Tweet)
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I also wonder about the significance of Ro52. Some of the commonly observed features like gastrointestinal dysmotility are not captured. https://t.co/UPljYf65vH
Alberta Hoi alberta_hoi ( View Tweet)
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#EULAR2022
How to Manage (HOT): Lupus Nephritis
Voclosporin is the new CNI
long term reno-ischemic effects need to be looked at https://t.co/8RqayemaRu
EnvisionRheumat ERheumat ( View Tweet)
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#EULAR2022
WIN session
Sarcoidosis – an update for rheumatologists
Clinical Approach https://t.co/AYOEDsnDZ6
EnvisionRheumat ERheumat ( View Tweet)
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#EULAR2022 COVID orals
OP0172
Swedish COVID19-Reuma registry with n=414 ARD + 61 controls
RTX n=145, ABA n=21
In MVA, use of RTX, ABA were a/w lower Ab response. We've known this about RTX; growing data for ABA as well? https://t.co/Es9bA54m8E
Rheum Cat rheum_cat ( View Tweet)
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Excited to share our recent work "IPAF: What the Rheumatologist Needs to Know."
@jeffsparks @UnaMakris @DrDavidKarp @UTSW_LungLadies @UTSWRheum https://t.co/O0BsrRyHx8 https://t.co/R3lQMGFgUb
Elena Joerns EJoerns ( View Tweet)
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🔥Hot off the press🔥
🆕Our Comments on various GC protocols in @IJRheum
The changing paradigm of glucocorticoid therapy in antineutrophil cytoplasmic antibody-associated vasculitis
https://t.co/4BjfkvPVAY https://t.co/gMXg7qQJWY
Kunal Chandwar kunalchandwar ( View Tweet)
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do we need another IL17a inhibitor? https://t.co/yf8cFNruzU
Peter Nash drpnash ( View Tweet)
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"Implementation (of guidelines) is key but remains the weakest part of the process" Dr. @DanielAletaha #EULAR2022 @RheumNow https://t.co/9ULIAA7dvg
Dr. Rachel Tate uptoTate ( View Tweet)
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Easy clinical tool for predicting lymphoma development at the time of #Sjogrens syndrome #EULAR2022 https://t.co/tQ6B0iVRnb
Christian Ammitzbøll RheumTweeter ( View Tweet)
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Dr Buch. ORAL Surveillance. MACE, VTE, Malignancy all more common in those with high (>20%) baseline CV risk or history CAD. HRs 1-2 for most but for VTE and high baseline CV risk, HR 6-11! @RheumNow #EULAR2022 POS0237 https://t.co/9DI4KotyOp
Richard Conway RichardPAConway ( View Tweet)
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Dr Elena Nikiphorou explaining how the Western diet can bring on and worsen inflammation joint disease symptoms. We should look to include more Omega 3 than Omega 6 in our diets #EULAR2022
PB https://t.co/nIKOSDPURU
ARD & RMD Open ARD_BMJ ( View Tweet)
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A very comprehensive overview of progress in the understanding of #IIM pathogenetic mechanisms outlining the role of
👉 Type 1 INF pathway
👉 Vasculopathy
👉 NETs
👉 Mitochondrial Dysfunction
#EULAR2022
Dr. Lisa Rider https://t.co/BXbXlYTHYM
Ashima Makol MD AshimaMakol ( View Tweet)