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EULAR 2022 Featured Industry Abstracts

d Jack Cush, MD

Below is a collection of several EULAR 2022 abstracts highlighted in recent press releases from companies sponsoring major clinical trials. You can search the EULAR site for these abstract and others here.

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GCA temporal artery

Giant Cell Arteritis Growing More Lethal

d MedPage Today

Mortality rates among patients with giant cell arteritis (GCA) in Canada's Ontario province rose by 15% from 2000 to 2018, a new study found, even as the general population saw declines in overall mortality.

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PSS.scleroderma.arthritis.contractures

Immune Checkpoint Inhibitor Associated Arthritis

d Jack Cush, MD

Immune checkpoint inhibitors (ICIs) have dramatically improved outcomes in numerous cancers but have been hampered by a growing spectrum of immune-related adverse events (irAEs). Rheumatic complaints may be less frequent than other irAEs associated with ICI in cancer patients. 

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Bridge Prednisone Use Fails to Improve Outcomes

d Jack Cush, MD

A one year, X-ray outcome trial has shown that the initial use of prednisone (high or low dose) in newly treated active early rheumatoid arthritis (RA) did not improve radiographic outcomes.

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Where is overall mattock disease following a covid vaccine range from 4.4 to 14.9% period this study of 4627 showed an 11.7% flare rate within 3 months of VAX #EULAR2022 abtr POS 0200 https://t.co/sxI4791rll
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Baricitinib fails in 2 phase 3 lupus trials, BRAVE I & II #EULAR2022 abtr POS 0190 https://t.co/ecGA2A42kP
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Voclosporin in lupus nephritis - good 3 year continuation data. #EULAR2022 abtr POS 0186 https://t.co/s4Dj6ZTh71
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Bridge Prednisone Use Fails to Improve Outcomes A one year, X-ray outcome trial has shown that the initial use of prednisone (high or low dose) in newly treated active early rheumatoid arthritis (RA) did not improve radiographic outcomes. https://t.co/Ugl05Mljwj https://t.co/zXYYTHE7yW

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Tuesday Night Rheumatology: HOT TOPICS IN RHEUMATOLOGY https://t.co/tMMrRU3sXa

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NEJM Image: Salt-and-Pepper Skin Changes in Systemic Sclerosis https://t.co/MVjFgMYBoI https://t.co/yIxsEp3xKz

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Dr. Jack Cush reviews the news, regulatory updates and journal reports from the past week on https://t.co/V10S4oVFsv. This week gout worries, mortality risks, measuring anti-drug antibodies and a better way in lupus? https://t.co/RWH0JoHdFA https://t.co/iEtfj5UnEC

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RNL 2022: Rheumatoid Arthritis - Best Management Last week's Tuesday Night Rheumatology, hosted by Dr. Jack Cush, featured highlights from the 2022 RheumNow Live Rheumatoid Arthritis - Best Management Pod, followed by a lively audience Q & A. https://t.co/trgaAqbB5J https://t.co/OiFd66ZanY

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Is Gout Protective Against Dementia? People with gout appeared less likely to develop dementia than age- and sex-matched peers, a database study from Korea found. https://t.co/I0eW805oqR https://t.co/BeQEcjxOIo

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Cardiovascular Risk in Calcium Pyrophosphate Deposition Disease A recent EHR study shows that acute CPPD crystal arthritis was significantly associated with elevated risks for non-fatal CV events. https://t.co/c0Nbjko3OQ https://t.co/SC9J80ROFT

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Watch: Who Killed Caravaggio? Peter Nash, MBBS, FRACP shares thoughts on what or who exactly killed Caravaggio six centuries ago. https://t.co/9iOlArIIpb https://t.co/GQX8aDZGjy

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Increasing Corticosteroid Use in Non-Hospitalized COVID-19 JAMA reports that despite NIH recommendations, non-hospitalized COVID infected patients were oftent prescribed systemic corticosteroids. https://t.co/1BADbI5j3z https://t.co/QtZZd7UJkc

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Retrospective pregnancy outcome study in 154 Rheumatic pts. Systemic sclerosis pts had higher risk of adverse preg outcomes (vs HC - 60.6% vs 10.0%; OR = 14; SSc had increase in 1st trimester miscarriage, preeclampsia, SGA & Preterm https://t.co/hfd6SsCRmr Conclusions

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Single center muscle bx of 860 pts muscle biopsy had 531 with IIM (61.7%), 253 with non-IIM (29.4%), and 76 undiagnosed (8.8%). 7.9% were classified as immune mediated necrotizing myositis, 40% DM, 9.5% synthetase synd, IBM 0.3% https://t.co/KTsjpu0qPY

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Long COVID Manifestations The acute consequences of a SARS-CoV-2 infection may be bothersome or devastating, but the long-term consequences may lead to so-called "long COVID" syndrome. Long COVID appears to affect up to 20% of those who survive COVID-19. https://t.co/Oh5R9xPKYD https://t.co/5iRVEjdWZW

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Disease modification has been defined in multiple disease areas but no widely accepted definition exists for SLE. Learn about the benefits & why there’s a need to consider therapies that modify the immunologic mechanisms of SLE. Sponsored by GSK USMA https://t.co/GV20emEpki https://t.co/onX7To2zvn

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