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Interesting potential upcoming SLE treatments
Data from China
Improvement of SRI-4 response rate compared to placebo
@RheumNow #RNL2022 https://t.co/VE5Tza7xt8
Robert B Chao, MD doctorRBC ( View Tweet)
Anifrolumab and lupus.
Don not forget Herpes zoster vaccination!!
Sonail Narain @RheumNow #Rnl2022 https://t.co/hNWaSHH27d
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
#ClinicalPearl Maybe..2 approaches that may Rx #SLE. More data needed but restoring IL2 or use of Telitacept latter w BLyS & APRIL effects (B cell signalling) #RNL2022 @RheumNow https://t.co/qjHZH9Xg0k
Janet Pope Janetbirdope ( View Tweet)
Safety in pregnancy still not clear #RNL2022 https://t.co/xs8bxja2VX
madan madanpadmajan1 ( View Tweet)
Great talk by Sonail Narain at #Rnl2022 @RheumNow
Take home message!! https://t.co/rT8WNPRtvB
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Targeting the BLyS-APRIL signaling pathway in SLE
Sonail Narain @RheumNow #Rnl2022 https://t.co/g3MbO4swKy
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Role of Anti-CD-19 CAR-T therapy in treatment of refractory SLE?
Case reports only thus far
@RheumNow #RNL2022 https://t.co/0dIid7viZ5
Robert B Chao, MD doctorRBC ( View Tweet)
“Physician global impression on RA control changes DMARD prescription, while patient global changes DMARD adherence” —Dr. Michaud #RNL2022
Ara Dikranian RumorDoc ( View Tweet)
Emphasizing what we should know. Do not stop or decrease HCQ - associated with SLE flares
@RheumNow #RNL2022 https://t.co/ko37cBOQPF
Robert B Chao, MD doctorRBC ( View Tweet)
Great presentation by Dr. Narain on Novel Treatment of SLE #RNL2022 https://t.co/l9LyH1oPhd
Dr. John Cush RheumNow ( View Tweet)
Poor prognostic factors and mortality in lupus and lupus nephritis.
Joan Merrill @RheumNow #Rnl2022 https://t.co/j6mn87f7QJ
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Plaquenil
▶️Immune system
Effect on toll like receptor and interferon production.
▶️ Effect on mortality
Decrease it.
▶️ Metabolic
Anti platelet , anti diabetic and anti lipid.
▶️Pregnancy
Decrease transmission of Anti Ro to baby
@RheumNow #Rnl2022
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Be aware of "Lupus podocytopathy"
non-immune complex mediated nephritis
can be similar to minimal change disease
may respond to immunosuppression
@RheumNow #RNL2022
Robert B Chao, MD doctorRBC ( View Tweet)
Could combination therapy from get go, work?!
Joan Merrill @RheumNow #Rnl2022 https://t.co/m1Mt78J4RX
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Dr. Joan Merrill reviews Lupus Nephritis at #RNL2022 @RheumNow https://t.co/bFiRp9xxTs
Dr. Rachel Tate uptoTate ( View Tweet)
Lupus podocytopathy.
Minimal change disease in lupus patient, no immune complex deposit.
Joan Merrill @RheumNow #Rnl2022 https://t.co/Ao2XEEMdb5
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Dr. Joan Merrill on Lupus Nephritis
Developing field of urinary markers for LN but not quite ready for primetime
@RheumNow #RNL2022 https://t.co/IrUiD3eJOP
Robert B Chao, MD doctorRBC ( View Tweet)
Lupus nephritis classes:
Do not forget to Look for ⬇️
▶️Crescent and tubulointerstitial findings are a poor prognosis.
▶️Microangiopathic changes (afferent and efferent arteriole) +- role of anti coagulation.
Joan Merrill @RheumNow #Rnl2022 https://t.co/06bjobCtZZ
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Lupus podocytopathy: emerging nonimmune complex mediated nephropathy. Consider in nephrotic syndrome pts w/ normal/FSGS renal bx. Can mimic minimal change. Approx. 1% of LN bx. May benefit from cyclosporine (podocyte stabilizer) & immunosuppression. Dr. Merrill #RNL2022 @RheumNow
Dr. Rachel Tate uptoTate ( View Tweet)
Dr. Joan Merrill on lupus at #RNL.. new Bx class lupus podocytopathy. May respond to immunosuppression and cyclosporine (podocyte stabilizer)
Dr. John Cush RheumNow ( View Tweet)