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Enzyme Porcupine inhibition of Wnt signaling is a promising treatment forsclerosteosis - rare Dz caused by SOST mutations & loss of functional sclerostin. Results in high bone mass & skeletal overgrowth (Sxs of facial paralysis, hearing loss, incr intracranial pressure https://t.co/Bgr5zoHyMG
Dr. John Cush RheumNow ( View Tweet)
JAMA Pt Education handout - Scleroderma https://t.co/UpK24WfyNF
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Dr. John Cush RheumNow ( View Tweet)
Genetic Sequencing in Rheumatology
Genetic sequencing as a research and diagnostic tool has expanded in medicine and rheumatology. An interesting review in Arthritis and Rheumatology suggests that despite currently modest use, there will be an expanded role for genetic
Dr. John Cush RheumNow ( View Tweet)
Everyone is entitled to his own opinion, but not his own facts.
- Daniel Patrick Moynihan https://t.co/VQTvdtm9cw
Dr. John Cush RheumNow ( View Tweet)
Is High Dose Aspirin Needed in Kawasaki Disease (KD)?
Does aspirin add any advantage to intravenous immunoglobulin (IVIG) alone in children with KD? A randomized clinical trial IVIG alone was not inferior to IVIG plus aspirin, suggesting that high-dose aspirin during initial https://t.co/uuCgDmgNif
Dr. John Cush RheumNow ( View Tweet)
Genetic Analysis of Asymptomatic Antinuclear Antibody Positive Patients
A large scale genomic population study found antinuclear antibodies (ANA) in up to 14% of the population; most with ANA are asymptomatic, and ANA production is not associated with significant genetic risk. https://t.co/Ltqf1yaaoy
Dr. John Cush RheumNow ( View Tweet)
Recent Medscape Physician Compensation Report 2025, MD Salaries dropped by:
Dermatology: -11%
Neurology: -6%
Urology: -6%
Plastic surgery: -4%
Cardiology: -4%
Ophthalmology: -4%
Gastroenterology: -3%
Rheumatology: -3% https://t.co/kNKuBwbL8J https://t.co/fA7d5A3wJp
Dr. John Cush RheumNow ( View Tweet)
Our Chief Medical Editor Leonard H. Calabrese, DO, (@LCalabreseDO) shares his reflections on the book: Masterclass in Medicine: Lessons from the Experts
@ClevelandClinic
https://t.co/gZhbrBLcnR
Healio Rheumatology HealioRheum ( View Tweet)
Rheums! Have a rheumatology question or case for Dr. Cush? Record it here and we may feature it on an upcoming podcast. Tell us your name and where you practice rheumatology.
https://t.co/uLoRmsAkiG https://t.co/ExthuSBSXs
Dr. John Cush RheumNow ( View Tweet)
Is High Dose Aspirin Needed in Kawasaki Disease (KD)?
Does aspirin add any advantage to intravenous immunoglobulin (IVIG) alone in children with KD? A randomized clinical trial IVIG alone was not inferior to IVIG plus aspirin, suggesting that high-dose aspirin during initial https://t.co/vThkP4AH6x
Dr. John Cush RheumNow ( View Tweet)
Full read state of the art review of treatments for Axial Spondyloarthritis
Concluding unmet needs:
-Suboptimal Tx Response
- Limited Drug Options
- No Biomarkers
- Extra-Axial Dz
- Non-Inflammatory Pain https://t.co/K3oqRCgTCP https://t.co/rkX2givwF8
Dr. John Cush RheumNow ( View Tweet)
🚨 New publication alert!
We review the latest advances in imaging for axial spondyloarthritis—from high-res MRI and synthetic CT to deep learning algorithms improving lesion detection.
🔗 https://t.co/oddjoFOGzM
#AxSpA #AIinMedicine
@XBaraliakos @WalterMaks @krystelaouad https://t.co/VwuUwYL1Xs
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Nelly ZIADE 🍀 Nellziade ( View Tweet)
Pregnancy-Related Deaths in the US
A CDC cross-sectional national study showed an increase in pregnancy-related deaths in the US from 2018 to 2022, with highest rates among American Indian, Alaska Native women, and non-Hispanic Black women.
https://t.co/H1s649GyiL https://t.co/MXnrQrAcrT
Dr. John Cush RheumNow ( View Tweet)
ACP: Best Practice Advice on Cannabis or Cannabinoids Use for Chronic Noncancer Pain
The American College of Physicians published a best practice advisory on cannabis or cannabinoids in the Annals of Internal Medicine.
https://t.co/B0eWstjN0Z https://t.co/IzSEIeosme
Dr. John Cush RheumNow ( View Tweet)
"Don’t ever let anyone tell you you ain’t strong enough" – Janis Joplin https://t.co/1B1YD5gDLk
Dr. John Cush RheumNow ( View Tweet)
Uveitis Risk with Slow Adalimumab Weaning
Patients with pediatric non-infectious uveitis (NIU) who achieved remission on adalimumab (Humira) had lower recurrence rates when the drug was withdrawn more gradually, a retrospective cohort analysis indicated. https://t.co/KgQsK6fVnr
Dr. John Cush RheumNow ( View Tweet)
2nd Opinions in Rheumatology
https://t.co/R4CjJHEaL4 https://t.co/0quDwdANyU
Dr. John Cush RheumNow ( View Tweet)
📢Calling all paediatrics! #BSR25 is almost here - Check out our top paediatric highlights from a packed Annual Conference programme 🔗Read our latest blog now: https://t.co/8uJMiqg2fW https://t.co/PAASNk3ZuF
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BSR RheumatologyUK ( View Tweet)
In our latest episode, @deodhara takes us behind the scenes of his research on IV secukinumab in #AxSpA. Discover key findings from the INVIGORATE-1 study, how it’s shaping treatment options, & what’s next in AxSpA research. LISTEN NOW → https://t.co/2IBixQSdpO @ACR_Journals https://t.co/HzcJw0pzWI
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American College of Rheumatology ACRheum ( View Tweet)
43 days to the Lupus Congress 2025 in Toronto 🦋...see you soon!
Abstract Sessions, Poster Tour Presentations, Plenary Sessions, Scientific Sessions, Debate Sessions, Patient Sessions, Fishbowl Discussion, and GALA DINNER on May 23!!!
@LupusCongress https://t.co/MaWjyofnIz
Zahi Touma, MD, PhD ZahiTouma ( View Tweet)
