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All News

Psoriatic Arthritis Responds to Tyk2 inhibition with Deucravacitinib

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d Jack Cush, MD

Mar 10, 2022

Deucravacitinib, a selective tyrosine kinase 2 (TYK2) inhibitor, was studied in a phase II trial of active psoriatic arthritis (PsA) patients and shown to be effective and safe.

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Could Anifrolumab Work in Lupus Nephritis?

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d Jack Cush, MD

Mar 10, 2022

Anifrolumab is effective and FDA approved for use in systemic lupus erythematosus (SLE); and now, a trial in lupus nephritis that almost shows benefit.

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Kawasaki Disease Guideline from ACR and Vasculitis Foundation

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d ACR

Mar 09, 2022

The American College of Rheumatology (ACR), in partnership with the Vasculitis Foundation (VF), released a new guideline for the management of Kawasaki disease that addresses diagnostic issues relating to Kawasaki disease, the treatment of high-risk patients, and the management of

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Combo MTX and Leflunomide in Psoriatic Arthritis

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d Jack Cush, MD

Mar 09, 2022

A recent study has shown that the combination of methotrexate (MTX) plus leflunomide (LEF) yields better disease control in psoriatic arthritis, but may not be as well tolerated as monotherapy with MTX.

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Baricitinib’s COVID-19 Efficacy in the RECOVERY Trial

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d Jack Cush, MD

Mar 08, 2022

Pre-print results of the RECOVERY Trial has shown that when baricitinib (BAR) is given to hospitalized severe COVID-19 patients, it results in significantly less mortality.

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Failed Osteoarthritis Pulse Ultrasound Study

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d MedPage Today

Mar 08, 2022

A promising therapy aimed at halting and even reversing the pathology underlying osteoarthritis (OA) of the knee failed to show any benefit in a randomized trial.

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CDC reports no cross-reactivity of serologic tests performance between Dengue, Zika and SARS-CoV-2 EIA. Study of febrile patients in Puerto Rico (DENV is endemic) with confirmed SARS-CoV-2, DENV, or Zika Dx. EIA specificity was ≥98% https://t.co/nXEBMuSDZL https://t.co/fa9yOqtxiI

Links:

https://bit.ly/3IWpVmx

Dr. John Cush RheumNow ( View Tweet)

Mar 10, 2022

Changing to a new biologic or sticking with the old one - a PsA patient chooses QD Clinic is sponsored by https://t.co/4UQlqwujiR (March 19 & 20, 2022 in Las Colinas, Texas) https://t.co/VJ5tuLN6ae https://t.co/OrxVBwNUsx

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Dr. John Cush RheumNow ( View Tweet)

Mar 10, 2022

Baricitinib’s COVID-19 Efficacy in the RECOVERY Trial https://t.co/PcQC6sQWyu https://t.co/Dqsq6BneM9

Links:

https://bit.ly/3w1D4a6

Dr. John Cush RheumNow ( View Tweet)

Mar 10, 2022

Failed Osteoarthritis Pulse Ultrasound Study https://t.co/6JpiVBOfuV https://t.co/3F4iRVZjUs

Links:

https://bit.ly/3634KAE

Dr. John Cush RheumNow ( View Tweet)

Mar 09, 2022

Single center study of individualized anakinra use in 47 autoinflammatory pts (32kids; 43% MAS; 40% systemic JIA). Off-label use in 38%, higher doses in 21 kids (5-29mg/kg); & 5 given IV anakinra; such doses were well tolerated without major AE. https://t.co/wQgw3YAPKX https://t.co/zL3HfdX4Ns

Links:

https://bit.ly/35I8ojF

Dr. John Cush RheumNow ( View Tweet)

Mar 09, 2022

Juvenile CADM: JAMA Case - 6 yoF with 4 yrs of rash on hands, feet, elbows, knees. No Resp to topicals. ROS rare cough & SOB; no weakness. Gottrons over hands, knee. Bx +, ANA+ 1:320, nl enzymes, MSA- See how she was Rx https://t.co/l26Y666JKZ https://t.co/XlzWNKILJU

Links:

https://bit.ly/3pPyCaB

Dr. John Cush RheumNow ( View Tweet)

Mar 09, 2022

Good review of Diagnosis and Treatment of Pulmonary Sarcoidosis in JAMA. - Lung progression (in only 10%) assoc w/ 12-18% 5yr mortality - Sx Sarcoid w/ Lung: start Pred 20 to 40 mg/d for 2 -6 wks - Steroid sparing w/ MTX, AZA or TNFi https://t.co/ylF8KR47gc https://t.co/VUvjYYC8gG

Links:

https://bit.ly/3pRMPnx

Dr. John Cush RheumNow ( View Tweet)

Mar 09, 2022

Shared Decision Making in PsA Changing to a new biologic or sticking with the old one - a PsA patient chooses QD Clinic is sponsored by https://t.co/4UQlqwujiR (March 19 & 20, 2022 in Las Colinas, Texas) https://t.co/Hc7ctWtj7A https://t.co/BAApPkxefc

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Dr. John Cush RheumNow ( View Tweet)

Mar 09, 2022

We are excited to announce that Dr. Philip Mease will be joining us at RheumNow Live, leading a presentation and discussion on Axial Psoriatic Arthritis & Fatigue and Central Sensitization. Join the discussion on March 19-20, on site or virtually! https://t.co/AIteIEHY9E https://t.co/ybXhIelSgM

Links:

https://bit.ly/3hQ9JY0

Dr. John Cush RheumNow ( View Tweet)

Mar 09, 2022

Gout is common but disproportionately affects certain groups (e.g., the elderly, Pacific Islander, Blacks). Ethnic links to gout were also recently shown to be linked to modifiable behavioral factors that may prove useful in managing gout patients. https://t.co/uvIuw3zFnq https://t.co/EZomBGQIyt

Links:

https://bit.ly/3IVLCD8

Dr. John Cush RheumNow ( View Tweet)

Mar 08, 2022

Study of 155 adult patients (PsA 61/AS 94) looked at labs & CV risk factors; found IL-18 elevated in peripheral PsA more than axial PsA & AS. Elevations were higher in PsA pts w/ ischemic heart disease correlated w/ atherogenic index & TG levels https://t.co/PQ3fBi8Qdo https://t.co/mewrcwhi4o

Links:

https://bit.ly/3KsQgJp

Dr. John Cush RheumNow ( View Tweet)

Mar 08, 2022

Another Kind of COVID Discussion Another kind of COVID (vaccination) discussion - kindness and respect for the patient QD Clinic is sponsored by https://t.co/4UQlqwujiR (March 19 & 20, 2022 in Las Colinas, Texas) https://t.co/XkUkqQ1Vli https://t.co/lrPd6jBMjt

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Dr. John Cush RheumNow ( View Tweet)

Mar 08, 2022

Tocilizumab Works Best in Non-Mechanical Ventilated COVID-19 Patients https://t.co/nUrAikqyPS https://t.co/CfmyB7Wwb6

Links:

https://bit.ly/3hNlA9b

Dr. John Cush RheumNow ( View Tweet)

Mar 08, 2022

Download this week’s podcast titled “When Less (Drug) is More (Activity) “ https://t.co/omdC3fElsb https://t.co/Hva4h9yEa9

Links:

https://bit.ly/3twOX5c

Dr. John Cush RheumNow ( View Tweet)

Mar 08, 2022

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