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Healthy Diets Prevent Gout in Women

d Jack Cush, MD

A prospective cohort from the Nurses’ Health Study has demonstrated that eating a healthy diet results in a 12% to 32% lower risk of incident gout and an even greater risk reduction (65% to 68%) when combined with normal weight and avoiding diuretics.

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ACR, guidance, guidelines

ACR Newly Revised COVID-19 Vaccine Clinical Guidance for RMD Patients

d ACR

The ACR has updated its clinical guidance for the use of COVID-19 vaccination in patients with musculoskeletal disorders (MSK). 

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The Last Word on JAK Inhibitor Safety & 1133 Study (1.28.2022)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.  This week a trifecta of Gout reports and the last word on the ORAL Surveillance study...

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Risk vs. Benefit Lessons from the ORAL Surveillance Study

d Jack Cush, MD

In an editorial in the current edition of the NEJM, Dr. Jasvinder Singh comments on the Oral Surveillance trial (Ytterberg et al.), a 4-year randomized, open-label, noninferiority, postauthorization, safety end-point trial, in high risk active rheumatoid arthritis patients over age 50 years.

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Systematic review of GI Safety of IL-17 inhibitors included 106 RCTs and 40,053 patients. Inflammatory bowel disease occurred in 0.4%; Most freq Sxs - diarrhea (2.5%), nausea or vomiting (0.7%), and gastroenteritis (0.2%). https://t.co/tv3QXHU1Hg

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Top Tweet in January Clinical trials generally fail in Sjögren's syndrome; but now a study shows that a biologic B cell inhibitor, ianalumab, met its primary endpoint with a dose-related decrease in disease activity (measured by ESSDAI) at week 24. https://t.co/j0BRs9snVH https://t.co/4OTmbNJ2GP

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RheumNow Live: Shorter Lectures, More Discussion - Rheumatologists like us, go to meetings like this; meetings that matter; meetings that change thinking We have a packed agenda with experts from around the world. https://t.co/94QmsCqSdj https://t.co/DIJrI8hwDa

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Study of Academic Clinicians showed that for every $1 generated though office visits (E&M coding) by 5 practicing academic rheums, $12.14 were generated through downstream revenue (mostly infusions). https://t.co/YQ1RL5JF9u

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The US FDA has published a 52 page report entitled, "DRUG SAFETY PRIORITIES 2021" covering, REMS, Sentinal program, Drug safety communications (eg, Xeljanz), nitrosamine impurities (NMDA), opioids, COVID drug safety & more...https://t.co/vcMZqkdsz5

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We are excited to announce that Dr. Ernest Choy will be joining us at RheumNow Live, leading a presentation on Precision Medicine in Rheumatoid Arthritis. Join the discussion on March 19-20. Invigorate, Instigate and Debate Rheumatology at #RNL2022 https://t.co/4uXQfRvRgc https://t.co/7KcPXadGcY

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Following a mild bout of COVID-19, Dr. Kathryn Dao, shares insights on the best way to handle mild cases whether it is yourself or a friend/family member who has COVID19. https://t.co/mevbQVNjPp ( @KDAO2011) https://t.co/CSzB9ChH3r

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Article in JAMA estimates that there are 110,000 LESS deaths per year when US adults aged 40-85 years or older had a modest increase in their modest increases in moderate-to-vigorous physical activity intensity per day (ie, 10 minutes per day) https://t.co/n1ictmjnqi

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2021 approved Efgartigimod (Vyvgart) for myasthenia gravis: (binds neonatal Fc receptor, stops Ig recirculation): pts w/ AChR Abs respond best (68% vs 30%). Common AEs include URI, UTI, HA; other AE: eyelid swelling, rash, and SOB. https://t.co/wQKZuAlXoR

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ICYMI: MMWR reports >40,000 pregnant women who received COVID-19 vaccination during pregnancy- VAX not associated with preterm birth or small-for-gestational-age at birth overall compared with unvaccinated pregnant women. https://t.co/GtRMsNrFnn

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ICYMI: How Preventable Is Rheumatoid Arthritis? https://t.co/epc6BvYKzq https://t.co/2hKIuE66zT

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ICYMI: NEJM clinical case -42 yoM w/ red, painful eyes, facial-nerve palsy OS, a large oral ulcer, and petechiae. +ANCA, +PR3. Skin biopsy revealed leukocytoclastic vasculitis with perivascular eosinophils. Dx eosinophilic granulomatosis with polyangiitis https://t.co/zXTQYfPa1t

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ICYMI: Physical Therapy is More Cost-Effective than Intraarticular Steroids in Knee OA https://t.co/My5xa8vEaP https://t.co/lGL57nwJiZ

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ICYMI: FDA Approves Skyrizi for Active Psoriatic Arthritis https://t.co/0HpoZYHK2V https://t.co/pvIC6ECqjF

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ICYMI: FREED study (asympt hyperuricemic without gout) showed febuxostat x 24 mos dint alter carotid atherosclerosis, but at 3 years, (Substudy of 1004 pts), showed FEB signif lowered risk of CVA, CV, renal renal events and death (vs PBO) https://t.co/x2pYrOBZVG

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Dr. Ernest Choy will be part of the Rheumatoid Faculty panel Q&A at RheumNow Live this March. Grab the mic & ask a question! Register Today! https://t.co/aJYMyKMGMn #RNL2022 https://t.co/oH4oG797XA

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