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DORIS - Defining Remission in Lupus

d Jack Cush, MD

Proponents of treat to target in systemic lupus erythematosus (SLE) have all agreed that "remission" should be the goal, but defining remission may be tricky in SLE.  A SLE Definitions Of Remission (DORIS)Task Force was convened in 2015 and first published their work in 2016.

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Giant Cell Arteritis Novel Treatment Options

d Richard Conway, MBBChBAO, PhD

Giant cell arteritis is associated with significant treatment related morbidity due to the dependence on glucocorticoids as a treatment option. After sixty years of therapeutic stagnation, these are exciting times in the management of GCA. At this year's ACR Convergence meeting, encouraging data will be presented on options for GCA.

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444 Bio-IR or csDMARD-IR #PsA pts were Rx w/ anti-IL-23, risankizumab 150 mg Sc vs PBO at Wks 0, 4, 16, @wk 24 RIZ had significantly better ACR20 resp (51% vs 26%, p<0.001). No differences in SAE (4 vs 5.5%) or SIE (0.9% vs 2.3%). https://t.co/os2AMgG4kc

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Drs. Jack Cush and Drs. Akhil Sood, Antoni Chan, Olga Petryna and Eric Dein, discuss highlights from Day 3 at the ACR21 annual meeting. Abstracts include #1367, #1044, #1444, #1083 and more. @akhilsoodsood @synovialjoints @DrPetryna @ejdein1 https://t.co/5lioAkgg2h https://t.co/YReoAepKw1

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Cardiovascular Disease for TNFi vs JAKi: Dr Jon Giles discusses abstracts #0831and #0958 presented at the ACR21 annual meeting. https://t.co/O90HInaS7z https://t.co/MdHVyxfkaW

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Watch Now: Drs. Janet Pope, David Liew and Eric Dein discuss TNF data presented at the ACR21 annual meeting, including abstracts #1251, #1442, #1448. ( @Janetbirdope, @drdavidliew, @ejdein1) https://t.co/UHmgmlrIqg https://t.co/0y03TFtJI6

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IL-35 (blood and urine) is elevated in #SLE pts with nephritis. Small study of 42 SLE pts serum IL-35 had 90% sensitivity & 65% specificity while urine IL-35 had 86.4% sensitivity and 75% specificity to establish the diagnosis of LN https://t.co/pK1rVCQQr9

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New Download Available! AOSD Disease Patterns Over Time https://t.co/IYePF20Nkn https://t.co/fOnc6jUl1b

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Dr. Jack Cush interviews Professor Edward Keystone, MD (University of Toronto) on the origins and science behind the 60/40/20 benchmark and outcomes in rheumatoid arthritis. https://t.co/Ve6zOQPxZJ https://t.co/8RuL2CCsOQ

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ICYMI:Food for Thought: "ITIS" Diet for Patients with Rheumatoid Arthritis: Dr. Akhil Sood ( @AkhilSoodMD) discusses abstract #1699 presented at the ACR21 annual meeting. https://t.co/bpQuzDGXCF https://t.co/9e2dYddsIx

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ICYMI: Data on Existing SLE Medications, Patient Centered Outcomes, and Exercise: Dr. Michelle Petri discusses data on existing SLE medications, patient-centered outcomes and the importance of exercise, presented Monday at the #ACR21 annual meeting. https://t.co/SQOLQRmQtp https://t.co/ZA1uISdGyk

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ICYMI: Update on Safety, Effectiveness of SARS-CoV-2 vaccines in SLE https://t.co/ihWapOaiNO https://t.co/daoIZtpsHH

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ICYMI: Drs. Jeffrey Sparks, Greg McDermott and Vanessa Kronzer discuss work in the area of respiratory disease in RA, mucosal paradigm, RA-ILD, bronchiectasis, as well as their experience as virtual attendees at the #ACR21 annual meeting. https://t.co/5BrxeJBWM2 https://t.co/m8CqyJ1L7A

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RheumNow Podcast - 60/40/20 Interview with Dr. Ed Keystone https://t.co/simAKtsQ7q

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ICYMI: Uveitis and Prevalence of Psoriasis in axSpA: Dr. Robert Chao ( @doctorRBC) discusses the best SpA abstracts he saw at the #ACR21 annual meeting: abstracts #1324 and #1311. https://t.co/XEJMyvKDnx

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ICYMI: COVID-19 in Patients with Primary Systemic Vasculitis and Polymyalgia Rheumatica Dr. Bella Mehta ( @bella_mehta) interviews Dr. Sebastian Sattui about abstract #0952 presented at the #ACR21 annual meeting. https://t.co/UN66qOGqRd

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ICYMI: Does Control of Inflammation Lower Cancer Risk? https://t.co/OBMIdPki7O https://t.co/zV04iAOjAz

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ICYMI: Multimorbidity, the presence of multiple overlapping chronic comorbid conditions, is increasingly common at first presentation of rheumatoid arthritis (RA), increasing as a person gets older and/or during disease progression. https://t.co/CL2xEyjKmd https://t.co/inoyahbkM9

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Food for Thought: "ITIS" Diet for Patients with Rheumatoid Arthritis: Dr. Akhil Sood ( @AkhilSoodMD) discusses abstract #1699 presented at the ACR21 annual meeting. https://t.co/wSPuGimFjP https://t.co/nc7bg1Odjk

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Infection Risk in Offspring Exposed to Biologics: Dr. Rachel Tate ( @uptoTate) https://t.co/oYpKpCix7Q https://t.co/0yIk9Qhc1h

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