All News

FDA.Safety.jpg

FDA Puts Boxed Warnings on JAK Inhibitors

d Jack Cush, MD

Based on the safety review of tofacitinib in Pfizer's Oral Surveillance (1133) study, the FDA has added serious boxed warnings to all three marketed JAK inhibitors (for inflammatory diseases) and formalized the recommendation that patients should be started on a TNF inhibitor (TNFi) before trying a JAK inhibitor. These recommendations apply to tofacitinib, baricitinib and upadacitinib.

Read Article
SI AS SpA ACR

TNF inhibitors and radiographic progression in axSpA

d Aurelie Najm, MD, PhD

A remaining challenge for clinicians is the ability to delay, if not completely stop, structural progression in patients with axSpA, whether they are diagnosed with radiographic (r-axSpa) or non-radiographic (nr-axSpA) disease.

Read Article
RheumNow Podcast square

Telemedicine Upside Interview with Dr. Alvin Wells

d Jack Cush, MD

In spite of the transformative growth of telemedicine during the COVID-19 pandemic, rheumatologists use of telemedicine is waning, much like the use of masks. Dr. Jack Cush interviews telemedicine guru, Dr. Alvin Wells, on the current state of telemedicine and what the future holds for telehealth in rheumatology.

Read Article
dementia,brain

Rheumatoid Arthritis, Dementia and Cognitive Dysfunction

d Jack Cush, MD

Rheumatoid arthritis (RA) has been linked to a higher risk of dementia and cognitive dysfunction, but interestingly this association has diminished in the last few decades with aggressive DMARD and targeted therapies..

Read Article
liver.jpg

Methotrexate and hepatic fibrosis: we must be doing something right

d David Liew, FRACP

Methotrexate may be a rheumatologist’s best friend, but a key part of counselling any patient about its use has always been the risk of hepatotoxicity.

Read Article
TNF inhibitors and radiographic progression in axSpA A remaining challenge for clinicians is the ability to delay, if not completely stop, structural progression in patients with (ax-Spa, whether they are diagnosed with -axSpa or nr-axSpA disease. https://t.co/Gn9vFlq0Bd https://t.co/CXdlU0HQG8

Links:

Dr. John Cush RheumNow ( View Tweet)
ICYMI:Methotrexate and hepatic fibrosis: we must be doing something right Despite methotrexate’s use in rheumatology, and the consequent frequency of patient counselling about it, relatively little is known about what precautions are absolutely required. https://t.co/AMvnQnMUUl https://t.co/aRzsy4ZA8z

Links:

Dr. John Cush RheumNow ( View Tweet)
ICYMI: New Insights into Uveitis in Spondyloarthritis Uveitis is the most frequent extra-musculoskeletal manifestation (EAM) in Axial Spondyloarthritis (axSpA). Read more on RheumNow. https://t.co/JF7TtE8SVJ https://t.co/Sw2b1WX5ko

Links:

Dr. John Cush RheumNow ( View Tweet)
ICYMI: Diagnosing (Bad) VEXAS: The Experts Speak Dr. Cush discusses Dr. Marcela Ferrada and Dr. David Beck to discuss VEXAS syndrome and abstract 1426, which was presented at the ACR21 annual meeting. https://t.co/oafDX0rJIl https://t.co/UoNpjABLNd

Links:

Dr. John Cush RheumNow ( View Tweet)
Guselkemab vs. Ustekinumab in PsA https://t.co/JCs5VpkyUK https://t.co/OzRtdWtqXp

Links:

Dr. John Cush RheumNow ( View Tweet)
ICYMI: DORIS - Defining Remission in Lupus Proponents of treat to target in systemic lupus erythematosus (SLE) have all agreed that "remission" should be the goal, but defining remission may be tricky in SLE. Read on... https://t.co/hVfzAtRzgY https://t.co/hSPz1eASzF

Links:

Dr. John Cush RheumNow ( View Tweet)
ICYMI: Giant Cell Arteritis Novel Treatment Options https://t.co/ywqGZNmHOa https://t.co/2hLESL1RjO

Links:

Dr. John Cush RheumNow ( View Tweet)
ICYMI: IL-35 (blood and urine) is elevated in #SLE pts with nephritis. Small study of 42 SLE pts serum IL-35 had 90% sensitivity & 65% specificity while urine IL-35 had 86.4% sensitivity and 75% specificity to establish the diagnosis of LN https://t.co/SgmGDSU8dZ

Links:

Dr. John Cush RheumNow ( View Tweet)

Telemedicine Upside Interview with Dr. Alvin Wells Dr. Jack Cush interviews telemedicine guru, Dr. Alvin Wells, on the current state of telemedicine and what the future holds for telehealth in rheumatology. https://t.co/iOpKqjIVuP https://t.co/emseMx4iZ0

Links:

Dr. John Cush RheumNow ( View Tweet)
Spondyloarthritis Panel Discussion: ACR21 Meeting Drs. Antoni Chan, Robert Chao, Rachel Tate, Sheila Reyes and Akhil Sood discuss abstracts #0562, #1919, #0907, #0364 and #0919 @synovialjoints @doctorRBC @uptoTate @RHEUMarampa @AkhilSoodMD https://t.co/g0ARcP26wt https://t.co/8Lpwpf6AI1

Links:

Dr. John Cush RheumNow ( View Tweet)
Watch Now: Can We Stop Medication in Systemic JIA? https://t.co/yRIb70YVME https://t.co/EJ2PmC6xKY

Links:

Dr. John Cush RheumNow ( View Tweet)
Third Time's the Charm - COVID Vaccination While on Rituximab https://t.co/3j0KeQtzw1 https://t.co/YvgpaDX7tv

Links:

Dr. John Cush RheumNow ( View Tweet)
Rheumatoid arthritis (RA) has been linked to a higher risk of dementia and cognitive dysfunction, but interestingly this association has diminished in the last few decades with aggressive DMARD and targeted therapies. https://t.co/T1feTkSKQv https://t.co/XElvgsGC0E

Links:

Dr. John Cush RheumNow ( View Tweet)
Best of PsA Day 4 - MACE in PsA https://t.co/NTM1GR7d5W https://t.co/ZxPJ8jDXhD

Links:

Dr. John Cush RheumNow ( View Tweet)
Watch: Rheumatic Diseases Can Take your Breath Away https://t.co/7Butbt50N3 https://t.co/4VV1myDXWV

Links:

Dr. John Cush RheumNow ( View Tweet)
×