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PsO vs PsA patient and disease characteristics COPPAR registry:
PsO pts 🔼mean BSA
Both 🔼 % of biologic therapy
sPGA and PASI 🔼PsO
🔽QOL and physical health in PsA
🔼daily work impairment PsA
Abst # 1779 #ACR21 @RheumNow
swethaann23 swethaann23 ( View Tweet)
🚫Infection risk after COVID vaccination: US database
536 954 Controls and 47 303 pts w/ RMDs
〽️BNT162b2 19 vs. 36/1000
〽️ mRNA-1273 16 vs. 33/1000 〽️Janssen 26 vs. 47/1000
Infections ⬆️ RA, SpA, SLE, SSc, Polymyositis
#ACR21 #AbstL16 @RheumNow
https://t.co/xzOaFIu06e
@RheumNow https://t.co/tmr4USETJ3
Links:
Aurelie Najm AurelieRheumo ( View Tweet)
#ACR21 2022 ACR/EULAR Large Vessel Vasculitis Criteria:
🌎One reason for updating 31 year old criteria -> now an international effort that better reflects heterogeneous global disease
@RheumNow https://t.co/6YWmabNzuH https://t.co/YXm85uQZCK
Links:
Eric Dein ericdeinmd ( View Tweet)
#ACR21 #Abstr1909 📢We need to stress the importance of hydroxychloroquine adherence to our patients. Adherence (>90% of the time) reduced premature CVD mortality by 52% in #rheumatoidarthritis and #lupus. The study didn’t adjust for smoking @RheumNow https://t.co/D9pGqwWhje https://t.co/R6r3cSexUB
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Looking forward to the #ACR21 roundup by Drs. Cush and Kavanaugh at 7pm EST tonight. Always entertaining and informative. A highlight of ACR for me. We met in person the last time in Atlanta #ACR19. It’s virtual & the link is at @RheumNow Hope to meet in person again #ACR22 🤞 https://t.co/pgAcBExL7G
Dr. Antoni Chan synovialjoints ( View Tweet)
Can we predict who will develop #RA-ILD?
Perhaps anti-MAA is the answer!
#ACR21 Abs#1916
👉🏼⬆️anti-MAA antibody assoc with incident ILD risk
👉🏼Associations are antigen &
isotype dependent
👉🏼Antibody measurement may be useful to risk stratify for RA-ILD
@RheumNow https://t.co/nC0OkuWtGU
Mrinalini Dey DrMiniDey ( View Tweet)
ORAL Surveillance: MACE and malignancy are getting all the attention...
but did you know that non-zoster infections are also more likely with tofacitinib vs TNFis?
#ACR21 ABST1684 @RheumNow https://t.co/GiBkvPYs4j
David Liew drdavidliew ( View Tweet)
ACR/EULAR Classification Criteria for Large Vessel Vasculitis (TAK/GCA), updated from prior to include imaging
Must emphasize typical disclaimers; these are for classification, not specifically for diagnosis
Great effort and useful result, esp for trials
#ACR21 @petercgrayson https://t.co/IYFyh5oYBT
Mike Putman EBRheum ( View Tweet)
⭐️Ustekinumab+MTX vs. UST+PBO in PsA?
➡️Additional MTX has no positive impact on UST efficacy for arthritis, enthesitis, dactylitis, skin, QoL, & function.
*️⃣Thus, no evident to add or maintain ongoing MTX when starting UST
Late-Breaking Poster#12. #ACR21 @RheumNow #ACRBest https://t.co/k96PPUtwct
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
#ACR21 2022 ACR/EULAR GCA Criteria
▶️Classification, NOT diagnostic!
⭐️Must be >50yo
⭐️Clinical, lab, imaging, and biopsy findings
+TA biopsy or Halo sign = 5 points, 6+ points needed for classification
@RheumNow https://t.co/6YWmabNzuH https://t.co/cZVrWA02U6
Links:
Eric Dein ericdeinmd ( View Tweet)
Once again #steroids are bad in #RheumatoidArthritis from 2 large admin databases in age >65 in Medicare data, not in younger pts -Optum data. Clear dose response #ACR21 #ACRBest @RheumNow abst#1915 https://t.co/XL93jty7C9
Janet Pope Janetbirdope ( View Tweet)
#ACR21 Abs#1915
👉🏼Chronic steroid use in older adults on stable DMARD therapy
assoc w/ ⬆️CV risk
👉🏼Risk even present among older adults receiving low dose ≤5mg/day
👉🏼Larger studies needed in younger healthier adults
@RheumNow https://t.co/Lsj5YBz7IG
Mrinalini Dey DrMiniDey ( View Tweet)
Congratulations @KenSaag the 85th President of @ACRheum Under your guidance we will flourish as a team that “is there for our members so they can be there for their patients”. #ACR21 #RheumatologyIsAmazing
David Karp DrDavidKarp ( View Tweet)
#ACR21 2022 ACR/EULAR TAK Criteria
▶️Classification, NOT diagnostic!
⭐️Must be <60 yo, needs vasculitis on imaging
⭐️Clinical criteria + imaging finding (more points for more arteries, 3 pt for abd aorta with renal or mesenteric involvement)
@RheumNow https://t.co/6YWmabNzuH https://t.co/fJka2a9tqm
Links:
Eric Dein ericdeinmd ( View Tweet)
HCQ adherence (>90%) associated with 52% reduced cardiovascular mortality in RA and SLE. Seen for MI, stroke, not VTE. Abstr#1909 #ACR21 @RheumNow https://t.co/5UncmqZVNp
Richard Conway RichardPAConway ( View Tweet)
Long-term low dose glucocorticoid use associated ⬆️cardiovascular risk. Clear effect in Medicare population (older), not evident in Optum (younger). Dose dependent. Abstr#1915 #ACR21 @RheumNow https://t.co/oFet3Hhsfo
Richard Conway RichardPAConway ( View Tweet)
Claims data looked at 21,114 #RA & #SLE pts - 4.3% had CV Death. The risk of CVD was worse w/ HCQ nonadherence (HR 1.08; 0.91-1.31) and better w/ HCQ adherence (HR 0.51;0.42-.66) HCQ nonadherence shows higher CV mortality #ACR21 Abst# 1909 https://t.co/di1mBliMN6
Dr. John Cush RheumNow ( View Tweet)
Retrospective cohort study FORWARD databank :
⭐️ 🔼opioid use was associated with higher HAQ-DI and BASDAI scores among patients with PsA or AS
Annualized avg opioid use and costs 🔼with 🔼HAQ-DI and BASDAI scores for patients in both cohorts
Abst#1117 #ACRBest @RheumNow https://t.co/KB9QUITbAe
swethaann23 swethaann23 ( View Tweet)
#ACR21 TM18
⭐️Spontaneous coronary artery dissection (SCAD) of LAD
▶️ +Sicca, Photosensitivity, malar erythema, alopecia, oral ulcers, arthralgias
▶️ ANA negative, dsDNA HIGH
Rare case of ANA negative SLE with odd presentation!
https://t.co/jfmVtZ4iOV @RheumNow https://t.co/pMHcColeUn
Links:
Eric Dein ericdeinmd ( View Tweet)
SpA & Pregnancy Outcomes?
➡️SpA pts txed w/ bDMARDs at conception are not at higher risk for adverse pregnancy outcomes compared to those w/o bDMARD
➡️Stopping bDMARDs after conception assoc w/ ↑ dz activity during pregnancy + after birth & ↑flares
Abst#1730 #ACR21 @RheumNow https://t.co/Y4c7vI0cgS
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)