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Knowledge Bowl at #ACR21
⭐️Which HLA allele confers an increased risk for anterior uveitis and inflammatory sacroillitis?
➡️HLA-B27
@RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
BAFF & APRIL support B cell development, diff, survival.
ALPN-303: Antagonist of both BAFF & APRIL
💠⬇️B cell fxn & Ab production,⬇️Plasma cells
💠⬇️UProt, dsDNA, renal immune complexes (mouse model)
💠Pending human studies
https://t.co/kzVpUDuNWs
#ACR21 Abst#1429 @RheumNow
Pedro Castillo _Castillo_Pedro ( View Tweet)
My summary article on some of the many abstracts at #ACR21 on #WorkParticipation in #axSpA.
Featured abstracts in this article:
#0358 https://t.co/LrZYWqCuOm
#0362 https://t.co/flL5MiqDL8
@RheumNow
https://t.co/tu5L0yIVIV
Links:
Mrinalini Dey DrMiniDey ( View Tweet)
Are you using less #rituximab in #SLE during #COVID #ACR21 @RheumNow #Lupus hub
Janet Pope Janetbirdope ( View Tweet)
#ACR21 Knowledge Bowl Final Question: Vasculitis Mimics: @RheumNow https://t.co/laD3oO8Uq9
Eric Dein ericdeinmd ( View Tweet)
1st Place in #ACR21 #Rheum Knowledge Bowl Gulls of Galveston
Congrats to Daniel Gonzalez and Aparna Das!
@RheumNow @UTMBProvost @UTMBInternalMed https://t.co/nXjy0CD1uY https://t.co/fAUTE3V8lo
Akhil Sood MD AkhilSoodMD ( View Tweet)
Knowledge Bowl at #ACR21
⭐️This disease featuring purple-red papulosquamous eruptions, on the hands and elsewhere, can have preceding painless erosive symmetrical arthritis at the DIPs, and has a 30% malignancy risk.
➡️Multicentric Reticulohistiocytosis
@RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Top Influencers of #acr21: @ACRheum @rheum_cat @RheumNow @RichardPAConway @CreakyJoints @KDAO2011 @alhkim More 📊 https://t.co/vyMAwk1Mia
Symplur Hashtags healthhashtags ( View Tweet)
Knowledge Bowl at #ACR21
⭐️This HLA allele can be seen in a certain vasculitis where panuveitis is a possibility and has a venulitis predilection
➡️HLA B51
@RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
If you need a #knee replacement move out of Ontario. More income disparity of access to #TKR in Ontario vs Pennsylvania. Lack of universal #healthcare in 🇨🇦. Oh Canada we fail. @RheumNow #ACR21 abst#1037 https://t.co/kobUlT3Ugr
Janet Pope Janetbirdope ( View Tweet)
Novel way to treat inflammatory arthritis!
A bioengineered probiotic bacterium, L. reuteri (LrS235) was found effective to reduce inflammation and clinical signs of inflammation in rats with inflammatory arthritis.
Abst # 1707 #ACR21 @rheumnow https://t.co/UC28yRlGYP
TheDaoIndex KDAO2011 ( View Tweet)
"Baseline and routine EKGS are NOT required for SLE patients just because they are on HCQ!" - Dr. HM Belmont. "The drug has been demonized due to its use in COVID patients. We don't need to hold HCQ for EMR alerts (e.g, with cipro, SSRIs, etc)." Abstr#1743 #ACR21 @rheumnow https://t.co/5Bxavo6dRg
TheDaoIndex KDAO2011 ( View Tweet)
Wager question that cemented the winners: @UTMB:
⭐️This monogenic disease can mimic Behcet's & occurs d/t mutat in TNFAIP3.
➡️Haploinsufficiency A20
Congrats to the winners & all contestants, including the top 2 finalists: @MGHrheumatology & @EmoryUniversity!
#ACR21 @RheumNow https://t.co/LZqsBKiPL8
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Anti-NETs antibodies in #COVID.
1️⃣ correlate➖ w/ SpO2/FiO2 ratio (IgG r=-0.17 IgM r=-0.30
2️⃣correlate➕ w/ ⬆️D-dimer (IgG r=0.33 IgM r=0.19
3️⃣ ⬆️ in pts requiring MV
In a study of 328 pts. Probably driving complement activation!
#ACR21 #Abst1430 @RheumNow https://t.co/2MCrLueTzN
Aurelie Najm AurelieRheumo ( View Tweet)
AQUILA study, SEC improved disease activity, depression of PsA patients in both men and women. Women showed overall higher burden of disease. SEC effective up to 52 weeks with high treatment retention rates irrespective of gender @RheumNow #ACR21 Abst#1334 https://t.co/9cPGq5M648 https://t.co/iTrkRWoot0
Dr. Antoni Chan synovialjoints ( View Tweet)
Low incidence of GI-related serious AE in pooled 1 year data from VOY1&2 and DISC1&2 trials of Guselkumab for PsA/PsO treatment
⭐️no new onset IBD or exacerbation of IBD
⭐️no uveitis, infections, TB
Abs#1342
#ACR21
@RheumNow
https://t.co/x3OmLgInV0
Robert B Chao, MD doctorRBC ( View Tweet)
⭐️ Wanna catch up with the latest news on JAKi safety trials presented at #ACR21? Our @Rheumnow interview with @ErnestChoy1 is out. Link below
https://t.co/zYb4rXcw1x https://t.co/i39xXnfC3Q
Aurelie Najm AurelieRheumo ( View Tweet)
You can <but not as frequently> treat to target in #RheumatoidArthritis with virtual v in person visits. 45 docs in 18 practices comparing in person to virtual. In person wins but not by a large gap! Abst#1448 @dansolomon @RheumNow #ACR21 #ACRBest session today coming up https://t.co/8lcuMW0bwb
Janet Pope Janetbirdope ( View Tweet)
SEC demonstrated significantly longer time to flare vs PBO w/ sustained improvement of ERA and JPsA signs and symptoms up to Wk 104. No new safety signals. Plenary Abs 1424 #ACR21 #RheumNow @RheumNow https://t.co/VF2HmJ3Ha9 https://t.co/ApYFusADHX
Dr. Rachel Tate uptoTate ( View Tweet)
RheumNow’s expanded coverage of the #ACR21 annual meeting is sponsored in part by @Novartis. All content chosen by RheumNow & its Faculty.
Dr. John Cush RheumNow ( View Tweet)