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Infections & Lupus (10.28.2022)
Dr. Jack Cush discusses the news and journal reports from the past week on RheumNow. This week more lupus nephritis, more drug induced lupus and more lupus infections that may kill.
Read ArticleGrowing Confidence in Biosimilars?
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Today, Cardinal Health released its third edition of Rheumatology Insights, a research report based on surveys with more than 100 rheumatologists nationwide that focuses on key trends
Read ArticleInfection: a Leading Cause of Death in Lupus
Analysis of a national database of hospital discharges from Spain shows that infections accounted for 25% of lupus deaths, making infection the most common cause of death in SLE.
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Update to Axial Spondyloarthritis Guidance
EULAR and the Assessment of SpondyloArthritis International Society (ASAS) has updated their guidance on axial spondyloarthritis (axSpA) management.
https://t.co/iAUXrVp1P3 https://t.co/bHwjI6xJUq
Links:
Dr. John Cush RheumNow ( View Tweet)
New ACR/EULAR Guideline Expands RA Remission Definition
Newly released guidance for defining remission in RA is expected to increase the number of patients achieving it while maintaining its ability to predict good objective outcomes.
https://t.co/ZZN3kAGW8F https://t.co/iaYUvxYHMq
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Dr. John Cush RheumNow ( View Tweet)
PSOAS study of 354 with long-standing ankylosing spondylitis & SI radiographic changes; but 23 lacked syndesmophytes. Lack of fusion was more likely in women & w/younger age of Sx onset. All were B27+, thus B27 may be assoc w/ SI dz, not spinal dz. https://t.co/QCyTCHjK6u https://t.co/gT3tFuZCDq
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Dr. John Cush RheumNow ( View Tweet)
2022 ASAS-EULAR Guidelines for Axial Spondyloarthritis
Assessment of SpondyloArthritis international Society (ASAS) and EULAR have published their 2022 update and recommendations for the management of axial spondyloarthritis (axSpA).
https://t.co/YI3ZKfaU9k https://t.co/4bbETabYaf
Links:
Dr. John Cush RheumNow ( View Tweet)
Mayo Clinic Biobank matched case-control study (1:3) of 212 incident RA cases Active work physical activity lowered risk of RA (aOR 3.00), while 3-5 servings high-fat foods, fruits/vegetables lowered risk (OR 0.45; OR 0.54). https://t.co/PW6XRxzcDi https://t.co/wXnu9T55Yb
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Dr. John Cush RheumNow ( View Tweet)
TNF inhibitors Dont Increase Cancer Risk! 4592 RA pts:TNFi Rx (2296) vs matched DMARD Rx (2296) pts. TNFi had a lower cancer risk than DMARD Rx (IR 6.5 vs. 15.6 /1000PYs]). TNFi had Lower HR GI CA (0.432), breast CA (0.146), GU CA (0.220) https://t.co/mf1g0LwjXR
Dr. John Cush RheumNow ( View Tweet)
Predictors of serious infection (SIE) in SLE? A prior SIE conferred the highest risk of subsequent SIE. Study of 346 SLE pts shows SIE rate of 3.8/100 Pt-Yrs. Other risk factors:
Damage accrual, comorbidity, Dz activity, CTX use https://t.co/hvAtpTUPml https://t.co/QkJp7ssOUU
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Dr. John Cush RheumNow ( View Tweet)
Celebrating my 10,000 followers on TikTok. @Rheum101 is where I make videos teaching rheumatology to the general public in 3 min bites. Topics include #SLE #Steroids #RA #ANA #RheumLabs #DMARDS #biologics #JAKi #osteoporosis #PsA and more #RheumEducation #NotMedicalAdvice https://t.co/WEXspp5v28
TheDaoIndex KDAO2011 ( View Tweet)
Hematoinflammatory diseases https://t.co/3Xd76ab7yP
Luis Caminal caminalm ( View Tweet)
⏫IgG4 🚫 IgG4 RD
Elevated IgG4 levels can be seen:
👉 Chronic infections like #tuberculosis
👉Lymphoproliferative malignancies
👉 Bronchiectasis, #asthma
👉 Primary sclerosing cholangitis
#RheumTwitter #MedTwitter #Rheumatology https://t.co/N3EDYjyFLf
Pankti Mehta PanktiMehta24 ( View Tweet)
Dr. Jack Cush discusses the news and journal reports from the past week on RheumNow. This week more lupus nephritis, more drug induced lupus and more lupus infections that may kill.
https://t.co/cpOTUsok7e https://t.co/5Ew7Hr9Mcd
Links:
Dr. John Cush RheumNow ( View Tweet)
Join Dr. Jack Cush and Dr. Arthur Kavanaugh as they discuss, dissect and deliberate about data presented at the #ACR2022 meeting in Philadelphia.
https://t.co/0DOBvpsV6r https://t.co/T8VrFlu6xq
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Dr. John Cush RheumNow ( View Tweet)
CONGRATS to Dr Jean Liew: from Bronte scholar to social media influencer https://t.co/f9ZrvxaPgB
Dr. John Cush RheumNow ( View Tweet)
RA is an independent risk factor for Thyroid Dz & AITD. Study of 250 RA & 248 non-inflammatory RMD controls. RA had more abnl TFTs (34% v 19%; OR 2.2), Overt hypothyroidism, Anti-TPO Abs, & AITD (21.5% vs 9%; OR 2.8). https://t.co/lRvY4VGkUc https://t.co/ibUqPiD9Bv
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Dr. John Cush RheumNow ( View Tweet)
Will we see you there? #ACR2022
What are you most looking forward to on the agenda? https://t.co/KQGHJtwboe
Dr. John Cush RheumNow ( View Tweet)
FDA Approves Upadacitinib for Non-Radiographic Axial Spondyloarthritis in patients with objective signs of inflammation who have had an inadequate response or intolerance to tumor necrosis factor (TNF) blocker therapy.
https://t.co/ieaYyznlec https://t.co/YafTOxh8Cr
Links:
Dr. John Cush RheumNow ( View Tweet)
Update to Axial Spondyloarthritis Guidance
EULAR and the Assessment of SpondyloArthritis International Society (ASAS) has updated their guidance on axial spondyloarthritis (axSpA) management.
https://t.co/XQId2RIaVz https://t.co/vNRYSV2jRh
Links:
Dr. John Cush RheumNow ( View Tweet)


