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RheumNow Podcast – Driving in Pain (8.20.2021)

d Jack Cush, MD

You know, I'm a very good driver. We all think we're great drivers - but consider what it's like to drive in pain: would you be a good driver? Also, I want you to consider the diagnosis of calcium pyrophosphate dihydrate disease (CPPD). But first, let's look at a study out of Scotland, looking at military service and greater risk of hip and knee replacement.

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PsA.Hands_.jpg

Oligoarticular vs. Polyarticular Psoriatic Arthritis

d Jack Cush, MD

A psoriatic arthritis (PsA) cohort analysis reveals many similarities and few distinctions between those who present with oligoarticular and polyarticular PsA.

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vaccine,mRNA,Covid,vial

Sustained Effectiveness of mRNA Vaccines Against COVID-19 Hospitalizations

d MMWR

The CDC has reported that mRNA vaccine effectiveness against COVID-19–associated hospitalizations was sustained over 24 weeks; but there is evidence of waning protection amongst the immunosuppressed.

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Breakthrough infections: As of Aug. 9, almost 74% of the 8,054 vaccinated people that were hospitalized with COVID-19 were above the age of 65, according to the U.S. Centers for Disease Control and Prevention. ~20% of those cases ended in deaths https://t.co/jaSmKv5pPS

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Oligoarticular vs. Polyarticular Psoriatic Arthritis https://t.co/lQVNdmWgMc https://t.co/Kswfkbp5nC

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The CDC has reported that mRNA vaccine effectiveness against COVID-19–associated hospitalizations was sustained over 24 weeks; but there is evidence of waning protection amongst the immunosuppressed. https://t.co/UpQjFgKTpE https://t.co/3dQ2jacwJD

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https://t.co/wM1iRxtHvk The interleukin-6 inhibitor, tocilizumab (TCZ), was studied in a cohort of difficult systemic sclerosis (SSc) and was shown to be effective in refractory joint and skin disease with good long-term retention rates and disease stabilization. https://t.co/XkJDVwJLwb

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ICYMI: Belimumab in Pregnancy? a study of 13 pregnancies in 13 pts, mean age 38 yrs.. There were 11 live births, 1 case omphalitis (recovered w Abx) . No fetal anomalies found. 6 pts (46%) w/ Hx of recurrent pregnancy loss, four had live births on BEL https://t.co/FJJhepa25M

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#RA & Driving studied w/ installed auto sensor-based instrumentation - 23 controls compared to 33 RA pts (1292 driving hrs): shows RA & worsening Dz severity assoc w/ poor vehicle control; Braking/accelerating & steering variability liked to CDAI levels. https://t.co/umXGAbuicz https://t.co/EYxVVkzxR8

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Are you holding Otezla, SSZ, or leflunomide post vaccination? @RheumNow @LCalabreseDO @CCalabreseDO @DrDavidKarp @RADoctor @JointMD @JYazdanyMD

k dao KDAO2011 ( View Tweet)

@AngusWorthing @rheumecraig @ravenswoodrheum @JointMD @RheumNow @LCalabreseDO @CCalabreseDO @DrDavidKarp @RADoctor @JYazdanyMD @alhkim Do we have data that NSAIDS and acetaminophen alter antibody response? I would rather pts take acetaminophen or ibuprofen post-vax than prednisone.

k dao KDAO2011 ( View Tweet)

New podcast available for download wherever you get your podcasts! We review the big stories on RheumNow this week. https://t.co/dbX9RN8ji5 https://t.co/WEf7yCR9km

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ICYMI Spirometry study in 2,008 #RA patients - compared to controls, RA has a higher risk of restrictive Lung dz (OR 1.36, 95%CI 1.21,1.52) and obstructive LD (OR 1.21, 95%CI 1.07,1.37) independent of confounders like smoking https://t.co/UWViAZtvYg https://t.co/VhgxascvEG

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US News & World Report Ranks Best Rheumatology Hospitals https://t.co/DgoE0On7So https://t.co/jkJcOGlJXo

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In case you missed it— Booster Shots for Rheumatology Patients on Immunosuppressive Medications https://t.co/dIzrv3B12u https://t.co/2x63osTNHh

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We all think we're great drivers - but consider what it's like to drive in pain: would you be a good driver? That and more on this weeks podcast. Download now. https://t.co/dbX9RN8ji5 https://t.co/27DnNPbyFj

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Treatment of RA may be difficult, as it is estimated that up to 10% of patients meet the EULAR definition of difficult-to-treat rheumatoid arthritis (D2T RA). Now a EULAR task force has promulgated several points to consider (PtCs) in managing D2T RA. https://t.co/w4EWHD3RC4 https://t.co/s4q7jpitC8

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HHS, FDA & CDC Joint Recommendation on COVID Booster https://t.co/pKlFjnlQeu https://t.co/ue0pMfEvfm

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Acupuncture (AP) studied in 440 men w/ chronic prostatitis/chronic pelvic pain syndrome (AP vs Sham). Responders were higher in the AP group at wk 8 and week 32 (61.5% vs 38.3%; adjusted odds ratio, 2.6) https://t.co/TOtUBE3Wvu

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RCT showing Midodrine is effective in treating Vasovagal Syncope. 133 pts with hx of median of 6 syncope episodes in the prior year; given MID or PBO. After 12 mos, MID had less syncope episodes (42% vs. 61% PBO; RR=0.69) https://t.co/5pCSaYB76m

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