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ICYMI: Clinical and Therapeutic Challenges in Connective Tissue Disease and ILD

Mrinalini Dey, MBBChir, MA(Hons) Cantab., MRCP, FHEA Jul 03, 2025

Connective tissue diseases (CTDs) and interstitial lung disease (ILD) represent a challenging intersection of systemic autoimmunity and progressive respiratory impairment. Research presented at EULAR 2025 continues to highlight the importance of CTD-ILD and the evolving landscape of therapeutic options for patients with autoimmune ILDs.

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ICYMI: Secukinumab promise in PMR is real

David Liew, FRACP Jul 02, 2025

Choice is not just good, it is often necessary, and secukinumab promises just that in both PMR and GCA.

Genicular nerve block (GNB) is effective intervention for Knee OA. Metanalysis of 6 RCTs & 420 KOA pts. GNB significantly reduced pain & improved function (p<0.003), w/ significant relief as early as 2wks and function by 12 weeks. https://t.co/NMtiQPICpw https://t.co/gVJ0TyuY01

Efficacy and Temporal Dynamics of Genicular Nerve Block in Primary and Secondar…

BMJ - UK population study of 1.5 million adults finds pts w/ autoimmune dz have twice the risk of affective disorders (depression, bipolar dz, anxiety) significantly higher (p<0.001) (28.8% vs 17.9% in gen. population. Signif regardless of age, sex, ethnicity, income, Fam Hx, https://t.co/dsJxkvD4Nu

JAMA Patient Education Page on what is Interstitial Lung Disease https://t.co/BDbV6I53NH https://t.co/1OtTiJHkdt

https://buff.ly/UNUgy2C

From 1990 to 2021, the global burden of OA from high BMI increased markedly. YLD (years lived w/ disability) rates of OA attributable to high BMI increased from 34 to 50.6 per 100,000 - higher in females, correlated w/ Socio-demographic Index levels https://t.co/RjTJFNEbYm https://t.co/tIqmn9eLQ6

Global burden of osteoarthritis attributable to high body mass index, 1990‐2021…

Japanese cohort study compared 12 pts w/ Stills Dz or intravascular lymphoma. Stills pt had significantly higher ferritin and IL-18 levels and IVL pts had significantly higher sIL-2R levels. https://t.co/Ecd6vNJTc4 https://t.co/KdEcpDeskA

Evaluation of clinical biomarkers for differential diagnosis of intravascular l…

ICYMI: ACP: Best Practice Advice on Cannabis or Cannabinoids Use for Chronic Noncancer Pain The American College of Physicians published a best practice advisory on cannabis or cannabinoids in the Annals of Internal Medicine. https://t.co/mQI2g4W4hX https://t.co/BhfQtI792M

ICYMI: ACP: Best Practice Advice on Cannabis or Cannabinoids Use for Chronic No…

In >228k CTD patients across France, ILD increased mortality risk across all CTDs. Proportion of incident CTD with ILD highest in IIM (37%). Up to 34% of CTD-ILD pts had progressive pulm fibrosis. Supports earlier ILD screening & vigilance in CTDs. @RheumNow #EULAR2025 #OP0033 https://t.co/nEiTWQEqsP

POCUS of the lung can detect subclinical ILD and can be a useful, inexpensive, easy to perform screening tool for CTD-ILD. #EULAR2025 @RheumNow https://t.co/HC0skwUKQG

Foot and ankle #OA is often underrecognized.. 1 in 6 people over 50 have foot OA! #EULAR2025 @RheumNow https://t.co/4wGSzC8dvi

How to patients with rheumatic diseases consume online health information? 78% used internet for health information 50% use it atleast a month 66% found online information superior 41% used social media! 80% using it to find treatment optio ns! @rheumnow #EULAR2025 https://t.co/ZcjwPaqsjT

Rheumatologists can’t ignore hypereosinopilic syndrome anymore, not when it borders on our diseases and therapies. Great takeaways on subtypes and therapies from Giacomo Emmi in an elegant talk #EULAR2025 @RheumNow https://t.co/yzQVt1fLKW https://t.co/kiX6kPPQP5

https://buff.ly/lAS7D8u

#EULAR2025 in numbers 💫5125 abstracts submitted from 95 countries 💫177 scientific sessions 💫350 speakers from 45 nations 💫Balanced gender split of speakers & chairpersons 💫Fresh sessions format 💫Integration of European Workshop for Rheum Research https://t.co/7WoknFuVLL

HLA-B27 Testing in Practice A single center study shows HLA-B27 testing is often performed by both by rheumatologists and nonrheumatologists for a wide array of reasons and often along with other serologic tests. Optimal use of HLA-B27 testing has yet to be defined. https://t.co/oq7GNhzwZd

TONIX pharm presented two phase 3 RCTs at #EULAR2025 demonstrating efficacy of sublingual cylcobenzaprine at bedtime in w/ significant reductions in Fibromyalgia pain scores. TNX-102 SL could be the 1st new FM drug to be FDA approved in >15 yrs. PDUFA (decision) date is 8.15.25. https://t.co/XNd8uYLQsJ

Assessment of Peripheral Arthritis in Spondyloarthritis Dr. Antoni Chan talks with Dr. Dafne Capelusnik about abstract POS0257 presented at the 2025 EULAR meeting in Barcelona. https://t.co/E6l6qvNnox https://t.co/gLbMjF406q

Assessment of Peripheral Arthritis in Spondyloarthritis | RheumNow

Trends and Innovations from Barcelona (6.20.2025) Dr. Jack Cush reviews highlights, trends and novel studies from EULAR 2025 in Barcelona from last week. https://t.co/iEiQI8GACt https://t.co/X27CuZb5wH

Trends and Innovations from Barcelona (6.20.2025) | RheumNow

Simple Measures are Effective in Knee Osteoarthritis Knee braces, water therapy and exercise are the most promising non-drug therapies for treating knee osteoarthritis, according to a new meta-analysis publishing June 18, 2025 in the open-access journal PLOS One by Yuan Luo of https://t.co/4VQpKQJwXu

IL-17 inhibitors - Long-term Extensions and Uveitis Dr. Peter Nash offers his perspective on data presented at the 2025 EULAR meeting in Barcelona. https://t.co/eQd0TcQn76 https://t.co/6Zog4LC8Aj

https://buff.ly/B5Wr82W

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ICYMI: Clinical and Therapeutic Challenges in Connective Tissue Disease and ILD

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