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Rheumatic Flares Uncommon After COVID Vax

d MedPage Today

Post-vaccination disease flares were uncommon among patients with rheumatic and musculoskeletal diseases who were inoculated against COVID-19, researchers found.

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morbidity,covid,heart,lung,brain

Multimorbidity Impairs Responses in Rheumatoid Arthritis

d Jack Cush, MD

A retrospective analysis of the ACR RISE registry shows that multimorbidity is not only common in patients with active rheumatoid arthritis (RA), but also impacts treatment choices and outcomes.

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Mumps,Parotid

CRESS – A New Composite Measure for Primary Sjögren's Syndrome

d Jack Cush, MD

Randomized clinical trials in primary Sjögren's syndrome (pSS) are fraught with fault and inconclusive outcome measures, including the more recently developed EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI).  There's a new composite endpoint outcome for RCTs in pSS, called the Composite of Relevant Endpoints for Sjögren's Syndrome (CRESS).

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kids,learn,book

Rheumatoid Arthritis Offspring Show Normal School Performance

d Jack Cush, MD

A prospective, longitudinal study of the cognitive development of children born to mothers with rheumatoid arthritis (RA) demonstrates normal development as measured by comparative school test scores.

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CRESS – A New Composite Measure for Primary Sjögren's Syndrome https://t.co/7tvjBvP3g4

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A prospective, longitudinal study of the cognitive development of children born to mothers with rheumatoid arthritis (RA) demonstrates normal development as measured by comparative school test scores. https://t.co/6Dfdnin1aI

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Cohort study of 66 874 postmenopausal women older than 50 years finds fracture to predict a greater risk of subsequent fracture (regardless whether 1st fracture was traumatic or nontraumatic). All such pts need OP assessments https://t.co/EQtDdZb8Vz

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Systematic review of Kawasaki Dz treatment (4 RCTs, 456 pts) shows MAb & anti-cytokine biologic use does not reduce Coronary artery abnormalities (RR 0.93; [95%CI], 0.65 to 1.32) vs IVIG, but Abs did reduce Rx resistence (RR 0.60) https://t.co/FJkQfxCkjB

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Congrats to Deborah Veis, MD, PhD, appointed to be the next editor-in-chief of Journal of Bone & Mineral Research Plus (JBMR Plus). Dr Veis is a professor in the Division of Bone & Mineral Diseases at Washington University School of Medicine https://t.co/9aOibSdhqC

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JRheum review: 40–50% of psoriasis pts have psoriatic nail disease NP). NP is an important predictor of enthesitis, which is associated with the early stages of PsA https://t.co/sEuih3CSgX

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ICYMI: FDA Approves IVIG in Dermatomyositis https://t.co/PoHtzDYekk The FDA has approved Octagam 10% [Immune Globulin Intravenous (Human)], as the first and only intravenous immunoglobulin (IVIg) formulation to be approved for adult dermatomyositis (DM). https://t.co/eAQa2oPOOf

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Hands-Down Rheumatology - Sarcoidosis usually presents as a monarthritis or oligoarthritis. Late sarcoid arthritis affects knees, ankles, fingers (dactylitis). Bony lesions show honeycomb trabecular pattern). https://t.co/85zvhk4Poz https://t.co/pb9ABL5O8a

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ICYMI: Potential Birth Defects with Hydroxychloroquine HCQ is one of the safest meds used in rheumatology, but there is new claims data suggesting a small increase in the risk of malformations associated with first-trimester HCQ use. https://t.co/k1LOQvWlVm https://t.co/Ka96e733rp

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A prospective, longitudinal study of the cognitive development of children born to mothers with rheumatoid arthritis (RA) demonstrates normal development as measured by comparative school test scores. https://t.co/6Dfdnin1aI https://t.co/rJFn9WuCgO

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Dr. John Cush RheumNow ( View Tweet)
AstraZeneca announced today that anifrolumab (Saphnelo or anifrolumab-fnia) was approved by the FDA for that treatment of adult patients with moderate to severe systemic lupus erythematosus (SLE) who are receiving standard therapy. https://t.co/22HVA32IAh https://t.co/xZNfepcDLQ

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Don't forget to register for the ACR Virtual Townhall Wednesday 8/4/21: 7 PM ET Re: COVID vaccination effectiveness for rheum patients w/real world data @ACRheum @alhkim @rheum_cat https://t.co/CKAwSLMv8R

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k dao KDAO2011 ( View Tweet)

"Fibromyalgianess" is highlighted as a risk factor for undue, extended glucocorticoid use in rheumatoid arthritis (RA) patients, according to Wallace and colleagues in Rheumatology. https://t.co/uv19GSZsBV https://t.co/aSFlV9zeGt

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Article in press: Can ANCA titers predict relapse in patients with GPA? Cohort study by @UofT_DoM - microscopic hematuria and MPO ab at month 12 predicted increased risk of relapse https://t.co/ks3Gj5iSLR

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Study from the UK BSRBR for #AS & 2043 pts showed 44% w/ at least 1 comorbidity. Each comorbidity was associated w/ 0.40 unit increase in BASDAI and 0.53 in spinal pain. More Dz activity w/ Depression, CHF and peptic ulcer, not CRP/ESR https://t.co/0vAnbjHicw

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Dr. John Cush RheumNow ( View Tweet)

FDA Approves Anifrolumab in active, moderate-severe SLE on background standard of care therapies. https://t.co/22HVA32IAh https://t.co/NxJ4sWTWfE

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