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OP0140 at #EULAR2021: ➡️Obs, prospect Nordic study characterized axSpA pts w/ high BASDAI + ASDAS & multiple bDMARD use (indicating difficult to tx dz) ➡️1 in 10 received at least 3 bDMARDs *⃣Multiple switchers were more often F, had higher b/l dz activity, & psoriasis @Rheumnow https://t.co/syq0szVWKe
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
⭐️TORTUGA = PII trial that showed filgotinib (Jak1-i) signif improv SPARCC MRI scores (BM edema) in the spine + SIJ vs PBO in pts w/ active AS ⭐️OP0141 = post-hoc analysis that showed stat signif ⬇️ of CANDEN MRI scores (new bone format) w/ filgot at wk12 #EULAR2021 @Rheumnow https://t.co/RIpYIMcx1Q
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
➡️Netakimab = IL17Ai approved for AS, PsA, & Pso in Russia & Belarus

Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)

Clive Kelly presents data from INBUILD on nintedanib in progressive fibrosing RA-ILD over 52 weeks FVC decline -82.6 (41.3) mL in nintedanib vs -199.3 (36.2) mL in placebo (p=0.037) @RheumNow #EULAR2021 Abstr#OP0124 https://t.co/MZwzNoq6LC
Richard Conway RichardPAConway ( View Tweet)
⭐️JUNIPERA: RCT of SEC in active ERA & JPsA (2-18yo, most on MTX) -Tx . (TP)1: SEC 75/100 mg till wk 12 -TP2: cont SEC or switch to PBO till wk 104 ⭐️SEC efficacious on JIA ACR30/70 ⭐️74% w/ resolution of enthes ⭐️Median T2flare in PBO in TP2 = 453d LB0004 #EULAR2021 @Rheumnow https://t.co/JsG2pXz9r6
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
What to tell pts about diet? *⃣Nutrition plays a role in inflammation in RMD & co-morbidities. What you eat matters! *⃣ LImit salt, replace w/ herbs *⃣ Consume low glycemic index foods. Soda ⬆️risk of RA in women *⃣⬆️omega-3 ⬇️omega-6 (dairy, eggs) #EULAR2021 @Rheumnow

Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)

#EULAR2021 POS0236 Comparison of work productivity b/w CBP w & w/o AxSpA - 2 years from SPACE cohort ⭐️AxSpA showed significant ⬇️ in work productivity loss (WPL) compared to CBP wo AxSpA Can use to counsel AxSpA patients that we have effective Rx for return to work @RheumNow

Eric Dein ejdein1 ( View Tweet)

#EULAR2021 POS0237: Gut dysbiosis linked to worse disease status in axSpA. ⭐️Dysbiosis in 33% of AxSpA vs 17% of controls wo rheumatic disease ⭐️Gut dysbiosis associated with worsening disease activity @RheumNow https://t.co/rRl4Zbs7xc
Eric Dein ejdein1 ( View Tweet)
BUT.....the SEC results were significant if you only looked at those with moderate to severe rotator cuff tendinopathy? Curious study, I think worthy of a well designed prospective trial. https://t.co/kqGink3sjU

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Dr. John Cush RheumNow ( View Tweet)

Baseline Vitamin D 😎☀️correlated with biologic response in RA pts. ⭐️EULAR good response: 19.6% Vit D >20 vs 4.2%⬇️Vit D ⭐️Remission: 14.4% ⬆️Vit D vs 3.2% ⬇️Vit D Abs#POS0100 #EULAR2021 @RheumNow

Robert B Chao, MD doctorRBC ( View Tweet)

Time to go raspberry picking? Rubus idaeus leaf extract 400mg and 200mg after 12 weeks ⬇️ VAS pain in knee OA compared to placebo ⭐️no effect on WOMAC, SF-36, 20m walking Abs#POS0281 #EULAR2021 @RheumNow https://t.co/QAiag2XjRh
Robert B Chao, MD doctorRBC ( View Tweet)
Fellow rheumatologists, make sure to take care of yourself! Latin America study ⭐️57% rheumatologists experienced burnout ⭐️associated with ⬇️age, ⬆️hours, ⬇️satisfaction, ⬇️happiness, ⬆️suicidal thoughts, income Abs#POS0302 #EULAR2021 @RheumNow

Robert B Chao, MD doctorRBC ( View Tweet)

MSK US before 1st clinic visit? Abs#POS0260 showed ⬇️ in time to diagnosis of inflammatory arthritis from 31 to 12 days and ⬇️clinical visits 2.8 to 2.1 How do you use MSK US in your clinic? #EULAR2021 @RheumNow

Robert B Chao, MD doctorRBC ( View Tweet)

Mavrilimumab (GM-CSFi) phase II trial of COVID-19 PNA and systemic hyperinflammation ⭐️65% risk reduction in ventilation/death ⭐️no sig difference in ventilation requirement ⭐️no serious AE Abs#LB0001 #EULAR2021 @RheumNow

Robert B Chao, MD doctorRBC ( View Tweet)

Excellent talk on SLE, APS abs pregancy ⭐️pregnancy counseling is important ⭐️aspirin 81mg in all pregnant SLE pts ⭐️do not discontinue HCQ ⭐️stable LN - can switch MMF to AZA Abs#6888 #EULAR2021 @RheumNow

Robert B Chao, MD doctorRBC ( View Tweet)

Close call between LLDAS and DORIS Remission as a treat-to-target in #SLE. Thank you for participating in the polls #EULAR2021 @RheumNow https://t.co/r3OnSrmQkH

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Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)

Results are out. The majority would use #anifrolumab to treat refractory skin and joints disease #SLE. Thank you for participating in the polls #EULAR2021 @RheumNow https://t.co/wguBCkhZ7B

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Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)

No clear winner here. The majority would use #IL23 inhibitors as either 2nd or 3rd line bDMARDs and for #psoriaticarthritis with severe #psoriasis. Thank you for participating in the polls #EULAR2021 @RheumNow https://t.co/b8wzaRVTqw

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Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)

This is by far the biggest rheum dx COVID vaccinated cohort described I'm aware of 👏 Looking forward to full paper, & we will need data with more pts, more details, cellular response etc. Nevertheless, invaluable & reassuring. So glad to see it at #EULAR2021 LB0003 @RheumNow https://t.co/jsHZjLdCTT
David Liew drdavidliew ( View Tweet)
6. Rheum disease activity was stable with COVID vaccination. (RA, PsA, axSpA, SLE - total n = 597) 7/ LB0003 #EULAR2021 @RheumNow https://t.co/xxkrunjPa0
David Liew drdavidliew ( View Tweet)
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