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Israeli study of all cause mortality in PsA vs general population
⭐️no increased mortality in PsA group
⭐️leading causes of death was cancer in both groups
⭐️age, male sex, BMI, socioeconomic status, PsO associated with ⬆️mortality, NOT DMARDs
Abs#OP0219
#EULAR2021 @RheumNow
Robert B Chao, MD doctorRBC ( View Tweet)
Metabolomic profiling for PsA showed vLDL, triglycerides; apolipoprotein B, glycoprotein acetylene associated with increased CV events…
Do you monitor cholesterol levels in your PsA pts?
Abs#OP0221
#EULAR2021 @RheumNow
Robert B Chao, MD doctorRBC ( View Tweet)
Talk about unmet need. We must get better Rx for #Sogren’s Syndrome! Large survey show quality of life v poor in SS & correlates with degree of dryness in lacrimal & salivary glands POS0102 #EULAR2021 @eular_org @RheumNow
Janet Pope Janetbirdope ( View Tweet)
If we want drugs to be effective in #Sjogren’s Syndrome we need to see activity. The #Eular SS disease activity index ~ESSDAI in 511 SS pts found >50% w moderate to severe values BUT how much is Reversible ie fibro, fatigue, scarred glands? POS0105 @RheumNow @eular_org #EULAR2021
Janet Pope Janetbirdope ( View Tweet)
Disappointed to have missed lots of interesting sessions at Day 3 #EULAR2021 but look forward to catching up, starting with the difficult-to-treat #rheumatoidarthritis session! I particularly like this helpful summary on complexities & factors to consider in patients with D2T RA. https://t.co/H8n9Q2QNDW
Mrinalini Dey DrMiniDey ( View Tweet)
Cool special effects in #EULAR2021 symposium: A practical guide to the use of JAKi in RA & SpA. Beamed in & out of talk like #StarTrek @eular_org @RheumNow https://t.co/y4qToeFKE7
Janet Pope Janetbirdope ( View Tweet)
What does this graph represent to you? To me: we have a whole lot of PsA that all work equally well..
It’s time for more personalized approach to PsA treatment!
Excellent talk by @DrLauraCoates
Abs#OP6937
#EULAR2021 @RheumNow https://t.co/1NKLfmH2y5
Robert B Chao, MD doctorRBC ( View Tweet)
Day 3 #EULAR2021 - A dose of #physicalactivity 🏃🏼 before conference to keep me sane with all interesting stuff presented https://t.co/jew2T9lnwB
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Similar efficacy of PsA enthesitis treatment between adalimumab and secukinumab
⭐️mean change and resolution of enthesitis similar
⭐️resolution of equal but ⬇️ in pts with ⬆️ baseline enthesitis activity
⭐️rate of relapse ⬇️ and similar
Abs#POS0194
#EULAR2021 @RheumNow https://t.co/uPE4kmotCY
Robert B Chao, MD doctorRBC ( View Tweet)
Interesting small study on US assessment of Achilles of PsA vs normal pts after exercise
⭐️significant different of PD signal in PsA group
⭐️5 non-PsA pts still had PD🤔
Would be interesting to further classify differences in PD intensity…
Abs#POS1058
#EULAR2021 @RheumNow https://t.co/SLhqq4wgCl
Robert B Chao, MD doctorRBC ( View Tweet)
#Polypharmacy of meds not related to RA ⬇️remission & more adverse events but not if adjusting for comorbidities- so many diagnoses with RA ⬇️outcomes only defined as >1 drug #EULAR2021 @RheumNow OP0098 https://t.co/lMazBDTPw1
Janet Pope Janetbirdope ( View Tweet)
#OP0224 Estimating clinical meaningful threshold for disease activity and improvement in composite measures of disease activity in 139 PsA patients over 3 clinical visits. Usefulness for clinics and further testing in different settings warranted
@RheumNow #EULAR2021 https://t.co/mwHJwIhRVE
Paul Studenic Stiddyo ( View Tweet)
#OP0228 Phase 3 RCT on Risankizumab - KEEPsAKE 2 -PsA with 49% prior bDMARD 95% prior csDMARD: week 24 results
PE: ACR20 51% active vs 26% on PLC
PASI90: 55% active vs. 10% PLC
#EULAR2021 @RheumNow https://t.co/UkZLcXTNnq
Paul Studenic Stiddyo ( View Tweet)
BEAT-LUPUS: Belimumab After Rituximab Delays Severe Flares https://t.co/dUJMKFkZ52 https://t.co/oAgKcGbW0k
Andy Vermaut AndyVermaut ( View Tweet)
#Eular2021 OP0289:
⭐️Remission off-Rx: SLEDAI=0 (minus serol), no IS
⭐️Remission on-Rx: SLEDAI 0, Pred<5mg, maintenance IS
⭐️LDAS: SLEDAI<=2 wo pred or IS
⭐️LLDAS: SLEDAI <=4, no maj organ, no new features, pred <=7.5+main
These states have ⬇️ damage accrual, rec'd T2T
@Rhuemnow
Eric Dein ejdein1 ( View Tweet)
My toe hurts & it’s a killer! Gout is related to ⬆️comorbidities - clusters incl no comorbidities to worse outcomes if CRF in gout. HTN⬆️ Gout has SNIPs assoc w HTN & May be the cause. Incident Gout assoc with Acute coronary syndrome OP0193 OP0192 #EULAR2021 @RheumNow @eular_org https://t.co/CS6o0T1FL2
Janet Pope Janetbirdope ( View Tweet)
#EULAR2021 OP0290: Cluster analysis of APLS
4 Clusters:
⭐️ 2ndary APS, non-criteria
⭐️ ♂️ with CV risks
⭐️OB morbidity
⭐️Isolated LA +
@RheumNow
Eric Dein ejdein1 ( View Tweet)
A Triple Header of RA Plenary Abstracts: Dr. Jonathan Kay #EULAR2021
Dr. Jonathan Kay reviews three RA abstracts from the opening plenary session at the EULAR 2021 virtual meeting: abstract OP0012; abstract OP0007; and abstract OP0006.
https://t.co/6GhSLXqysd https://t.co/h2k00GzHE5
Links:
Dr. John Cush RheumNow ( View Tweet)
Difficult to treat RA pts cycle through more advanced therapies! Kind of obvious but in N=363, 9.4% with advanced Rx were difficult to treat vs 39% if > 1 ts\bDMARDs. Worse pts had ⬆️disease duration. Drug resistance over time? POS0405 @RheumNow #EULAR2021 @eular_org
Janet Pope Janetbirdope ( View Tweet)
Imagine being top expert for 37 years. World RENOWNED, won 🏅’s. Then there’s a crisis, IN YOUR FIELD, & as you step up, you’re degraded at every turn by a con man. Yet you carry on your duty cuz 🇺🇸 depends on it.
THAT’S professionalism.
THAT’S Dr Fauci https://t.co/DkVyfAQHsp
🇵🇱Reality Dose🇺🇸 LRPow79 ( View Tweet)