Genes Linking Rheumatoid Arthritis and Osteoporosis

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Rheumatoid arthritis is a common disease affecting an estimated 17 million people worldwide. The disease is caused by immune cells attacking the joints and can result in pain, swelling, and damage to the cartilage and bone.

COVID-19 and Long-Term Risk of Autoimmune and Autoinflammatory Disorders

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A Korean population based study found that people infected with COVID-19, especially severe COVID-19, had an increased risk of autoimmune and autoinflammatory connective tissue disorders.

Advances in the treatment of autoimmune hepatitis

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Autoimmune hepatitis (AIH) is a chronic, progressive liver disease caused by immune system dysregulation that targets the liver. If untreated, AIH can lead to severe complications, including cirrhosis and liver failure. 

A Keto Diet for Autoimmune Disorders?

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Scientists have long suspected the keto diet might be able to calm an overactive immune system and help some people with diseases like multiple sclerosis.

Now, they have reason to believe it could be true.

Virtual Yoga Effective in Chronic Low Back Pain

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A randomized trial of 140 adults with chronic low back pain (CLBP) demonstrated that virtual yoga instruction resulted in significant improvements in CLBP patients compared to the wait-list control group. 

Happy Diwali (11.1.2024)

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Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.

GLP-1 Inhibitor Reduces Knee Osteoarthritis Pain

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Semaglutide (Wegovy) reduced pain and improved physical function in patients with obesity and knee osteoarthritis, a randomized trial showed.

SGLT2 Inhibitor Protective Effects in Lupus

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Systemic lupus erythematosus (SLE) outcomes were assessed based on whether they received sodium-glucose co-transporter 2 inhibitors (SGLT2i), in the setting of comorbid type 2 diabetes (T2D).

Filgotinib Efficacy and Safety - 3 Years Later

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Filgotinib, the rheumatoid arthritis (RA) oral drug that never made it to the U.S. market but is sold across Europe, Great Britain, and Japan, remained effective for 3 years for most registration trial participants who continued in a long-term extension study, researchers said.

Swapping is Better than Cycling in Psoriatic Arthritis

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A real-world cohort study suggests that psoriatic arthritis failing to respond to TNF inhibitors (TNFi) may do better if they subsequently swap to an IL-17 inhibitor, rather than cycling to another TNFi.

Treatment Options for Dupuytren’s Contracture

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The NEJM reports that in a randomized, controlled, head to head trial, collagenase injections were non-inferior to limited fasciectomy in the treatment of Dupuytren’s contracture.