All News

gout podagra inflammed

Gout Flare and Treatment Studies Lacking in Severe Chronic Kidney Disease

d Jack Cush, MD

Gout is a common comorbidity amongst those with chronic kidney disease (CKD), with the added challenge of choosing best therapies in the setting of declining renal function.  A systematic literature review notes significant deficiencies regarding the efficacy and safety outcom

Read Article
cardiac2.jpg (keep)

Early Diastolic Dysfunction in Premenopausal Women with RA

d Jack Cush, MD

A two-dimensional/Doppler echocardiography of rheumatoid arthritis (RA) detected premature, clinically quiescent diastolic function.

Read Article
gout,MTP,tophi

Starting Febuxostat During an Acute Gout Flare

d Jack Cush, MD

A randomized controlled trial in gout patients has shown that starting febuxostat during an acute gout flare was without ill-effects and did not prolong the gouty attack.

Read Article
drug,capsules,antibotic

Early Antibiotic Use Increases JIA Risk

d Jack Cush, MD

A population based Swedish study of birth records shows that antibiotic exposure in first three years of life to be associated with a future risk of juvenile idiopathic arthritis (JIA), although infections during fetal life or childhood did not increase risk of JIA.

Read Article
TONIGHT! the ACR is holding a " Just Diagnosed: Now What? Patient Webinar" - this will feature Academy-nominated screenwriter & patient Emily Gordon ("The Big Sick") with Rheumatologist Stuart Kassan, MD, register here: https://t.co/TOCgOuV0Ng

Links:

Dr. John Cush RheumNow ( View Tweet)

Analysis of 508 #RA pts (over 10 yrs) in the BeST study shows joint swelling at baseline resulted in half w/ re-swelling later and significantly increased risk of same joint swelling during follow-up (OR 2.37, 95% CI 2.30 to 2.43, p<0.001) https://t.co/a7zH4YRAkq

Links:

Dr. John Cush RheumNow ( View Tweet)

PROCEED study of 300 pts with chronic, DXA proven bone loss in half (osteopenia in 39% and osteoporosis in 17%) with higher fracture rates. Such pts should undergo screening for osteoporosis. https://t.co/7fgeAk85vu

Links:

Dr. John Cush RheumNow ( View Tweet)

Are you an Expert in Still's disease, Periodic Fevers, FMF or Autoinflammatory Dz? I will add you to our expert referral listing on https://t.co/LYd3dtU295. DM me to get on the list! https://t.co/lt8YMPOpK2 https://t.co/QxXHMvayTG

Links:

Dr. John Cush RheumNow ( View Tweet)
U.S. Preventive Services Task Force (USPSTF) reaffirmed its recommendations that pregnant women at a high risk of preeclampsia should take a daily aspirin regimen at the end of the first trimester https://t.co/DiV7p6g8vL

Links:

Dr. John Cush RheumNow ( View Tweet)

Finnish Pop study 939 #RA pts shows highest healthcare costs linked to high Dz activity & comorbidity. Clusters: C1) young w/ low costs & activity, C2) chronic pain, disability, fatigue, C3) high cost/dz activity, less pain, C4)comorbidities w/ $$$ https://t.co/Azc35zyA9J

Links:

Dr. John Cush RheumNow ( View Tweet)

RA DMARD use gleened from 86 rheumatologists recording Rx choices/reasons on next 12 pts. Total: 1027 RA pts, 621 already on b/ or tsDMARD (68% TNFi, 21% JAKi). ~Half who switched given another TNFi . Reasons: LOE, dz worsening https://t.co/zpjSO25wsh

Links:

Dr. John Cush RheumNow ( View Tweet)

EULAR has received reports of tocilizumab shortage in several countries, including Germany, Portugal, Belgium, and Scandinavia. The UK and France are aware tocilizumab concerns, but have not yet reported actual shortages https://t.co/7QpjZTXXAK

Links:

Dr. John Cush RheumNow ( View Tweet)

A longitudinal study from Iceland shows an increasing number of native joint infections (NJI), with iatrogenic, postarthroscopic infections being of particular concern. Read more… https://t.co/n82PpZ7a96 https://t.co/j3gzZ9g0QV

Links:

Dr. John Cush RheumNow ( View Tweet)
DEA has warned of an increase in illegal counterfeit pills containing fentanyl & methamphetamine. These often look Rx opioids (Oxycontin, Percocet, Vicodin), Xanax or Adderall. DEA seized >9.5 million fake pills (more than last 2 yrs) https://t.co/Y0gJ4XrV1a

Links:

Dr. John Cush RheumNow ( View Tweet)

Study Finds U.S. Generic and Biosimilar Savings Totaled a Record $338 Billion in 2020 https://t.co/hPR0nGd6jp

Links:

Dr. John Cush RheumNow ( View Tweet)

Biosimilar update: 31 FDA approved biosimilars, but only 60% made it to market. 2015 to 2019, drug spending grew 6.1%, biologic spending grew 14.6%; biologics are 43% of US drug spending. Most biologics at ~30% discount. https://t.co/4paYH8yVLQ

Links:

Dr. John Cush RheumNow ( View Tweet)

MMWR shows the safety of a 3rd (booster) dose of the mRNA vaccine to be same as the 2nd dose AEs. V-safe data on 3rd dose (n=12,591) showed local or systemic effects (79% or 74%) to be same as 2nd dose (78% or 76%) https://t.co/LcD0ARlWJ2

Links:

Dr. John Cush RheumNow ( View Tweet)

#RA patients had an an increased risk of mortality after CABG (HR 1.50; 1.28-1.77); and a higher risk of MI following CABG (HR 1.61; 1.28-2.04). A retrospective Finnish study comparing RA (n= 378) to nonRA patients (n = 7560) https://t.co/cGGsrLs1V2

Links:

Dr. John Cush RheumNow ( View Tweet)

Tymlos (abaloparatide), for the postmenopausal osteoporosis, has a label update on the MOA, now reads as: "Once-daily...abaloparatide stimulates new bone formation on trabecular & cortical bone surfaces by stimulation of osteoblastic activity." https://t.co/AC9JvtmIdZ

Links:

Dr. John Cush RheumNow ( View Tweet)

Case controlled study suggests that intraarticular steroid injections is associated with increased (HR 8.56; 3.29-22.3) risk of rapidly destructive hip disease (RDHD); at a rate of 5.4% (5.1 mos post injx) w/ JSN, osteolysis, fem head collapse https://t.co/grX5bO4495

Links:

Dr. John Cush RheumNow ( View Tweet)

How well do you know this week's rheumatology news?
Take the rheumIQ quiz
Take the RheumIQ Quiz

×