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Consumption of Alcohol and the Risk of Gout
Alcohol is a risk factor for gout and flares. While the inciting potential differs among alcohol types, are these differences sex specific?
https://t.co/CzE9ZSEN9f https://t.co/e4WBSBlNEo
Dr. John Cush RheumNow ( View Tweet)
Scleroderma skin findings in pts w/ skin of colour (SOC) - Raynauds was common but SOC pts had fewer hallmark Sxs: telangiectasias, calcinosis, digital swelling (complicating Dx). SOC had more severe pulmonary Dz & increased mortality, Atypical skin findings… https://t.co/8XkelxqvYE https://t.co/JOw8OSNjzw
Dr. John Cush RheumNow ( View Tweet)
Diagnosing Seronegative Sjogren's Disease
Sjögren disease (SjD) is highly prevalent, but diagnosis may be challenged if anti-SSA antibodies or a labial salivary gland biopsy are negative. A recent cohort analysis suggests a novel autoantibody profile has predictive value SSA… https://t.co/v1Es7vVim2 https://t.co/RKxa2Iyeq0
Dr. John Cush RheumNow ( View Tweet)
IV Methylprednisolone in Giant Cell Arteritis
A retrospective study in giant cell arteritis (GCA) patients suggests there is no added value using higher dose, intravenous methylprednisolone (IVMP) in early GCA.
https://t.co/5udYabU5z5 https://t.co/5FHhBnAX2j
Dr. John Cush RheumNow ( View Tweet)
Anterior Cruciate Ligament Injuries are more commone in Female Athletes compared to males playing same contact sports. From 1990-2020, ACL injuries decreased in males by nearly 30%, but did not change in women, who are also less likely to return to sport https://t.co/EiyU440vRT https://t.co/QvYiSOVQZr
Dr. John Cush RheumNow ( View Tweet)
Cohort study shows GERD in 1539/1632 (94%) #SSc patients & 450/469 (96%) of SSc-ILD pts. GERD didnt influence ILD Dx or severity. But GERD Rx (PPI, H2RA) assoc w/ improved survival in those Scleroderma pts with ILD (p = 0.002) https://t.co/stQkpbmBCP https://t.co/e4BBz5c0av
Dr. John Cush RheumNow ( View Tweet)
The new Covid KP.2 booster vaccines are becoming available throughout the US. Besides high-risk (e.g. age 65+, immunocompromised, comorbidities), one of the most important reasons to get boosted, often overlooked, is to reduce #LongCovid risk by ~50%. Agree with Marks at FDA… https://t.co/SgX7JiPRzH https://t.co/i0W4xadxjW
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Eric Topol EricTopol ( View Tweet)
Causes of Carpal Tunnel Syndr: obesity, repetitive wrist movements, pregnancy, RA, PsA. but also Sjögren's syndrome, Behcet's disease and systemic sclerosis (weaker) https://t.co/ssrs8UJEpX
Dr. John Cush RheumNow ( View Tweet)
Gluten can be "a wicked antigen". Full read Review of the potential role of gluten in inflammation and autoimmunity. Undigested gluten peptides can be modified by luminal transglutaminase or delivered to gut mucosal immune cells https://t.co/eonHfpZZiN https://t.co/iKwbzg2Lbu
Dr. John Cush RheumNow ( View Tweet)
A Family History of Arthritis?
Using data from the population based All of Us Research Program, a self reported history of arthritis and related conditions was associated with an increased risk for arthritis, osteoporosis, and carpal tunnel syndrome.
https://t.co/SApbPLHquQ https://t.co/hOamnYyRoz
Dr. John Cush RheumNow ( View Tweet)
Tobacco is a risk factor for hidradenitis suppurativa (HS). Korean population study finds 3761 HS out of 6 million. Those who quit smoking developed less HS (adj HR 0.68; 95% CI, 0.56-0.83) https://t.co/4HF0Z5HORk https://t.co/ZilX4EzAa9
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Dr. John Cush RheumNow ( View Tweet)
Pulse Steroids with Tocilizumab in Giant Cell Arteritis
A pilot study assessed pulse methoprednisolone with weekly subcutaneous TCZ in patients with large vessel-GCA (LV-GCA) and showed that a sizeable minority will relapse after the TCZ is discontinued.
https://t.co/gGrSY3U1t9 https://t.co/zuspadaY9t
Dr. John Cush RheumNow ( View Tweet)
Overview of Cannabinoids for Rheumatic Pain disappoints because not much is really known or studied well. They may improve pain, but come w/ mild-mod side effects. Conflicting evidence contributes to practitioner and patient uncertainty https://t.co/eI07SXbbem https://t.co/ZDvdFcLXh4
Dr. John Cush RheumNow ( View Tweet)
Severe Alopecia Areata or Universalis - if you stop the JAK inhibitor, Hair loss occurs quickly, but can be recaptured. Severe Alopecia Areata. Substudy of the baricitinib BRAVE-AA1 RCT, 80% of those who D/C vs 8% of those continuing, lost BARI benefits https://t.co/YcfmegdvK6 https://t.co/GIwVy4ac6U
Dr. John Cush RheumNow ( View Tweet)
Global Biologics Market size is valued at USD 408.5 billion in 2023 and is projected to grow ~8.25% annually. https://t.co/2RTHIgJOP5 https://t.co/gfndut5wc0
Dr. John Cush RheumNow ( View Tweet)
Higher Cancer Rates (8.16.2024)
Dr. Jack Cush reviews the news and journal reports from the past week on https://t.co/V10S4oVFsv, noting his concerns about diet, cancer, ILD, death and dosing challenges.
https://t.co/thNOPkYWRM https://t.co/ZFwvE80e7Q
Dr. John Cush RheumNow ( View Tweet)
IgG4-related disease
Nearly any organ can be affected
▶️Salivary glands
▶️Lacrimal glands
▶️Orbit
▶️Pancreatobiliary system
▶️Lung
▶️Kidney
▶️Retroperitoneum
👉🏽https://t.co/758F5iuYwT
via @RheumJnl https://t.co/ipONrygHmc
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Dr Ai Lyn Tan DrAiLynTan ( View Tweet)
New! 📣Best Practice Guidelines for the management of Haemophagocytic Lymphohistiocytosis (HLH) aka Macrophage Activation Syndrome (MAS) from @NHSGIRFT @RheumatologyUK Remember the 3Fs Fever, Falling Counts, Ferritin and follow the HLH pathway to guide management… https://t.co/8oDyUbsm9W https://t.co/S0MDi3TkNk
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Dr. Antoni Chan synovialjoints ( View Tweet)
Metanalysis of 12 studies shows that being edentulous (or having < 20 teeth) was associated w/ higher risk (HR 1.66; 1.32–2.09) critical confounders also confirmed that tooth loss as a risk factor for Cardiovascular mortality (HR=1.52, 95% CI: 1.28–1.80) https://t.co/PStGlxmCC3 https://t.co/ZDzaytj9dY
Dr. John Cush RheumNow ( View Tweet)
Anti-Inflammatory Diet yields a lower risk of Dementia. UK Biobank study shows patients w/ type 2 diabetes, heart disease, or stroke who were on an anti-inflammatory diet had a 31% lower risk for dementia vs. a pro-inflammatory diet https://t.co/OjHq3BBOfd https://t.co/tG9vO59IEc
Dr. John Cush RheumNow ( View Tweet)
