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One-Third Rheumatoid Risk from Lifestyle
Analysis of the NHANES (National Health and Nutrition Examination Survey) data suggests that one-third of the risk of developing rheumatoid arthritis (RA) in the USA is attributable smoking, obesity and alcohol intake.
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British registry 801 axial SpA pts; 646 did not hve fibromyalgia at baseline & 46 (7%) developed FM over time. Of 115 axSpa w/ baseline FM, 77 (2/3) recovered. FM more likely with high Dz activity ((OR 1.27) & widespread pain (OR 1.14) https://t.co/4jOdaXIJuB https://t.co/ruOYj5HmMX
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Dr. John Cush RheumNow ( View Tweet)
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Our Top January Tweet:
Urate Lowering Therapy During Acute Gout
Acute gout has its well-defined protocols, and most state that urate lowering therapy should be continued; but does ULT affect outcomes in an acute gout attack?
https://t.co/aDHpU1qrlu https://t.co/6xDwyVjuyC
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Dr. John Cush RheumNow ( View Tweet)
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Multiple intraarticular steroid injxs NO better than placebo. Analysis of 6 RCTs show no diff in pain than PBO (−0.47, 95% CI −0.62, 0.31). 14 RCTs + 2 Observ. studies show IA steroids may cause mor cartilage loss or risk of joint replacement (HR 2.54) https://t.co/jCLq4jWn4Y
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Dr. John Cush RheumNow ( View Tweet)
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Everyone longs for normal. Normal may have changed, died, or been put off. But tomorrow morning, normal is waking up and looking to you for guidance
Dr. John Cush RheumNow ( View Tweet)
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Sign up for RheumNow Live, March 20 and 21st. CME credits available.
https://t.co/uwxOVh142F https://t.co/GqkCLBGl62
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Dr. John Cush RheumNow ( View Tweet)
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Download our latest resource--Televideo Joint Exam Checklist.
https://t.co/XnyCW2eak8
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Dr. John Cush RheumNow ( View Tweet)
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The RheumNow podcast is now up--listen in on SoundCloud, RheumNow or Apple/Android car play.
Rheumatology Burnout?--Dr. Cush reviews the top articles from the week of 1/29/21.
https://t.co/HiX7qMFU6b https://t.co/KbaZ6XjHG6
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Dr. John Cush RheumNow ( View Tweet)
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Calculating Serious Infection Risk in IMID Patients
Predictive modeling of data derived from the DANBIO registry (of treated IMID patients) revealed a 4 fold increased risk of serious infection in those starting biologic DMARD treatment.
Read more: https://t.co/i2GwiCvCx6 https://t.co/9sZ79LyZ7u
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Dr. John Cush RheumNow ( View Tweet)
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High Placebo Responses in SLE Trials
A systematic review in randomized controlled trials (RCTs) of non-renal, non-neuropsychiatric systemic lupus erythematosus (SLE) patients showing unexpectedly high placebo responses.
Read more: https://t.co/zUPsVFEz4n https://t.co/Gk7ke4hBwY
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Dr. John Cush RheumNow ( View Tweet)
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QD Clinic Podcast for the week of Jan 29 - Pearls from Practice This wk:
Arthritis &Crohn's
Rhabdo or Not
Dadgummit, Where's Waldos COVID Vaccine?
"I Don't Know"
A Tale of Two Gouts
https://t.co/7ndYSOgh5R or listen on iTunes https://t.co/FHJv01AAbC https://t.co/780P7Bdw8F
Dr. John Cush RheumNow ( View Tweet)
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RheumNow Podcast is up - Rheumatology Burnout (1.29.2021) - Vaccine #s, Colchicine in COVID, Rheums #2 in Burnout? Endometriosis & RA risk, Comorbidity as predictors. https://t.co/HiX7qMFU6b or listen on iTunes>>https://t.co/FHJv01AAbC or on SoundCloud>> https://t.co/0BfqGhxgQj https://t.co/j9nHMs4C6d
Dr. John Cush RheumNow ( View Tweet)
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Lupus Nephritis Despite Low Level Proteinuria
https://t.co/awxvsvwGTg https://t.co/e6DV6sfiN5
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Dr. John Cush RheumNow ( View Tweet)
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2016 Deloitte report on top 10 healthcare innovations (Spot on!):
1 Next gen sequencing
2 3-D printing
3 AI
4 Immunotherapy
5 Point of care diagnostics
6 virtual reality
7 social media for Pts
8 Biosensors/trackers
9 Telehealth
10 Convenient care https://t.co/yWaqzM9pFC
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Dr. John Cush RheumNow ( View Tweet)
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ACR Convergence 2020 Fireside Chats – Top presentations in nr-axSpA, AS, axial PsA
Sponsored by Novartis Medical Affairs
Unable to attend all the key sessions at #ACR20? Listen to the experts as they present their views on the top abstracts.
https://t.co/r5Cf4WS63s https://t.co/NmDXrTPGXq
Links:
Dr. John Cush RheumNow ( View Tweet)
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Several studies have shown that Xray progression has lessened in recent yrs - presumeably from more aggressive Rx by Rheums! Still - Predictors of Xray long term damage = high ESR/CRP, baseline xray damage, -CCP/RF positivity https://t.co/2iaMiaquEV https://t.co/cgEP4QBvL4
Dr. John Cush RheumNow ( View Tweet)
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JAK Inhibitor Misses Endpoint in Safety Study. Now What?
Pfizer announced results Wednesday from its FDA-mandated postmarketing safety study of tofacitinib (Xeljanz), and they don't bode well for the drug and possibly others in its class.
https://t.co/EPVdAdPP37 https://t.co/Box5NaxsKV
Links:
Dr. John Cush RheumNow ( View Tweet)
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News: #COVID19 risk may be reduced with #biologics and #JAKinhibitors, but increased with #glucocorticoids, Italian researchers report in @ArthritisRes https://t.co/zIef2aNCns
Medicine Matters rheumatology Rheum_Matters ( View Tweet)
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SELECT-PsA2, UPA vs PLBO in refractory PsA, @ARD_BMJ
Better ACR20 (57% vs 24% PLBO, NNT~3) and ACR50 (32% vs 5% PLBO, NNT~4). Decent PASI 90 (30% vs 6%, NNT~4)
Similar adverse events to RA pop. Nice to have another option, esp in refractory dx! https://t.co/Zz2WYqswT2
Mike Putman EBRheum ( View Tweet)
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My #rheumatology clinics now inundated with patient questions re: #CovidVaccine. I'm looking forward to new #CovidVaccine Guidance expected from the newly-convened #ACR Task Force, forthcoming on February 11th.
Jeffrey Curtis RADoctor ( View Tweet)