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#ACR20 RA treatment recommendations:
On administration of MTX 👇@Rheumnow https://t.co/XPXx8dq8gY
sheila RHEUMarampa ( View Tweet)
Draft #ACR20 Rx Recs for RA: discontinue MTX over biologic or tsDMARD in "patients that strongly want to discontinue", conditional recommendation supported by SEAM-RA Abst#939 @RheumNow https://t.co/U7cDhHIYzA
Eric Dein ejdein1 ( View Tweet)
Draft #ACR20 Rx Recs for RA: on max tolerated MTX - add bio or tsDMARD conditional recommendation over triple therapy (MTX, HCQ, SSZ). @RheumNow. https://t.co/s6fKEW8czc
Eric Dein ejdein1 ( View Tweet)
Draft #ACR20 Rx Recs for RA: Use MTX, starting oral but remember MTX tricks to maximize success. Folic acid, split dosing, SubQ all keys per Dr. O'Dell to maximize @RheumNow. https://t.co/8K9BjotZha
Eric Dein ejdein1 ( View Tweet)
Novel predictors of early mortality in a cohort of GCA pts from Portugal:
🚩Older age at dx
🚩Tongue claudication
🚩Prior tx w/ anticoag
BP treatment at dx - predictor of early survival. @RheumNow #ACR20 abs1935 https://t.co/TGJNnZ8vTQ
sheila RHEUMarampa ( View Tweet)
Draft #ACR20 Rx Recommendations for RA: MTX monotherapy conditionally rec over csDMARD dual or triple Rx, MTX+TNFi @RheumNow https://t.co/jyjRD5aadN
Eric Dein ejdein1 ( View Tweet)
Rituximab in AAV: how to dose?
Should we be giving:
- 'haem dosing': 375mg/m2 x4 doses
- 'RA dosing': 1000mg x2 doses
Systematic review says: no difference
Reassuring given the variation in practice in real life!
#ACR20 ABST2048 @RheumNow https://t.co/Jf4Ue6HRRL
David Liew drdavidliew ( View Tweet)
#ACR20 @RheumNow https://t.co/Duu2VK7Yes
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Prelim. results: Immunogenicity of adjuvanted #HerpesZoster subunit #vaccine in #RheumatoidArthritis patients taking #JAKinhibitors
- Most RA pts on JAKi have sufficient antibody response to HZ vaccine
- Acceptable safety profile
Abs#1997 #ACR20 @RheumNow
https://t.co/8HWAIwOATD
Mrinalini Dey DrMiniDey ( View Tweet)
Rheumatology reimbursement by CMS:
"If all goes well, in a few months, you will see a 16% increase in rheumatology."
- From ACR Advocacy Updates
@RheumNow #ACR20 Abs#5M017
Robert B Chao, MD doctorRBC ( View Tweet)
Checkout this session live now for an update on RA treatment guidelines (last updated in 2015)! #ACR20 @RheumNow https://t.co/Y4Ax3E4OHb
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
#ACR20 @RheumNow https://t.co/ccySqHFEb9
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Poll results are in! 50% of those that responded note that they recommend breathing exercises, yoga, and increase dietary intake of turmeric and ginger to their RA patients! #ACR20 @RheumNow https://t.co/04vOUOzRtj
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Dr Benard reports an SLR and meta-analysis of 27 studies comparing 2 rituximab regimes in AAV. 375mg x4 and 1000mg x2 equivalent. Remission in 91% vs 85%. Similar adverse event rates @rheumnow #ACR20 Abstr#2048 https://t.co/I0feVuZ8iy
Richard Conway RichardPAConway ( View Tweet)
Anakinra in #Stills disease - Double blind, placebo controlled RCT in Stills disease total 12pts, 6 placebo, 6 Rx grp. All pts reached ACR70 at week 2 without fever and sustained it at 12 weeks. 5/6 reached ACR90 @RheumNow
#ACR20 ABS#1633 #ACRbest https://t.co/9E4vm7WzhP
Bella Mehta bella_mehta ( View Tweet)
Poll results are in! 48% of those that responded are not yet convinced of the benefits of omega-3 fish oil supplements in pts w/ RA! #ACR20 @RheumNow https://t.co/B6f8ecWj07
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Wonder if you can predict which pts you can successfully taper off bDMARDs? Abst#1538 from Denmark showed that a neg IgM-RF (OR 0.26) & low Doppler serum score for 24 jts predicted successful discontinuation of bDMARDs at 2yr f/u in RA pts w/ DAS28-CRP<2.6. #ACR20 @RheumNow https://t.co/CbJTguxaoa
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Just a reminder:
inflammatory arthritis irAEs can occur at almost any time after immune checkpoint inhibitor cancer immunotherapy is commenced.
@LoyolaChicago #ACR20 ABST1566 @RheumNow https://t.co/qdEpNpzdNs
David Liew drdavidliew ( View Tweet)
I am glad now that chloroquine is not available (permanent back order) in Canada as results of high retinal toxicity w chloroquine was sobering & changed my practice. I won’t use it long term @RheumNow #ACR20 @CRASCRRheum abstr#1825 https://t.co/1RQi41uV1B https://t.co/lc9za22Zw1
Janet Pope Janetbirdope ( View Tweet)
A large observat study showed no difference in risk of major CV events in RA pts that were newly started on either MTX or HCQ. A greater stroke risk but lower risk of MI & hospitalized HF was seen in MTX initiators. #Abst1993 #ACR20 @RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)