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A large observat study showed no difference in risk of major CV events in RA pts that were newly started on either MTX or HCQ. A greater stroke risk but lower risk of MI & hospitalized HF was seen in MTX initiators. #Abst1993 #ACR20 @RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Dr Kaellmark reports on immunogenicity of adjuvant herpes zoster subunit vaccine in RA patients treated with JAKi. 40 RA patients and 20 controls. Satisfactory serological responses and tolerability seen. @rheumnow #ACR20 Abstr#1997 https://t.co/UlDe4NllU0
Richard Conway RichardPAConway ( View Tweet)
Dr. N Nikolov #FDA reviews role for rheum meds in #COVID19 and outlines guidance for trial design for CV19 therapeutics #ACR20 @rheumnow https://t.co/0oPvBN5mgF
k dao KDAO2011 ( View Tweet)
Study out of China, #ABS1892 shows that patient reported outcomes using self assessments are important in AS T2T and decreasing flare rates #ACR20 @RheumNow. https://t.co/ebGtVUg8IV https://t.co/oXvGxQSjtn
Dr. Rachel Tate uptoTate ( View Tweet)
What are you doing at 12pm today on this #ACR20 Monday? I will be listening to @LCalabreseDO discuss the importance of #empathy in rheumatology @HealioRheum @RheumNow https://t.co/E1cH39z64p
Cassandra Calabrese CCalabreseDO ( View Tweet)
#ABS0597 All PR-COIN centers found telemed visits met provider needs & 18/19 centers believed telemed visits met pedi-rheum pt needs. Reasons for in-person visit included presence of active dz, worsening condition, & parent request/desire. #ACR20 @RheumNow https://t.co/yun6QCv4fX https://t.co/l9BrVMdJEa
Dr. Rachel Tate uptoTate ( View Tweet)
Abatacept in RA and ILD Patients: Dr Richard Conway (@RichardPAConway) #ACR20
https://t.co/e31VsnXFq5 https://t.co/sCrqLtXFFc
Links:
Dr. John Cush RheumNow ( View Tweet)
The 'triple M' irAEs (myositis/myocarditis/MG): one of the rheumatic irAEs where autoAb are freq pos
Nice systematic review:
any autoAb+ 61% tested
MG+ 59% tested
MSA+ in 27% tested (18/67, 11 had myositis alone)
@NilashaGhosh @lovetolearn27 @got_rheum #ACR20 ABST1574 @RheumNow https://t.co/utSj8yY0fd
David Liew drdavidliew ( View Tweet)
#FDA updates #ACR20 @rheumnow
labeling/warning changes:
belimumab- mortality removed
abatacept - angioedema added
baricitinib -hypersensitivity rxn added
gabapentin & pregabalin - respiratory depression added
k dao KDAO2011 ( View Tweet)
Do you routinely request for HLA-B27 in young patients w/ IBP? @RheumNow #ACR20
sheila RHEUMarampa ( View Tweet)
Deucravacitinib TYK2i for PsA
Phase2b 16wk, Double-blind, Placebo, RCT
⬆️ACR20/50/70 response vs. PBO
⬆️HAQ-DI response, enthesitis resolution, MDA vs. PBO
*⃣No serious AE
@RheumNow #ACR20 Abs#L03 #ACRbest https://t.co/9Klu2aeEj2
Robert B Chao, MD doctorRBC ( View Tweet)
When you give IA steroids for knee OA how long do you tell pts it will work for @RheumNow #ACR20 @CRASCRRheum abstr#1650
Janet Pope Janetbirdope ( View Tweet)
Plenty of great #telemedicine posters in "Measures & Measurement of Healthcare Quality" session! Abs#1584 reports telemedicine improves access to #rheumatology clinics & adherence, eg in those prev without adequate transport provision. #ACR20 @RheumNow
https://t.co/KwVxqcqu7n
Mrinalini Dey DrMiniDey ( View Tweet)
@uptoTate @RheumNow Agree. MD global is Often SJC taking into consideration activity severity and location of joints. Ex SJC of two ankles or knees is higher MD global than 2 MCPs. All N of SJC are not =. @RheumNow
Janet Pope Janetbirdope ( View Tweet)
Using a panel of urinary prtns, data from this study show transferrin, AGP1, ceruloplasmin, MCP1 & sVCAM1 are sig. ⬆in active LN pts.
More studies req'd for confirmation.
Utility in monitoring renal response to tx?
@RheumNow #ACR20 abs1796 https://t.co/3Zicpz3uDd
sheila RHEUMarampa ( View Tweet)
IA steroids for knee OA did NOT ^ X-ray progression to TKR vs IA Hyaluronic acid! Data from 2 cohorts, n=792 knees. Similar X-rays for single & multiple injections of either Rx. Not Randomized but helpful! Abstr#1652 @RheumNow #ACR20 @CRASCRRheum https://t.co/1yzr5QkIzV
Janet Pope Janetbirdope ( View Tweet)
New PT-CDAI showed agreement w/ MD(DO)-CDAI at id-ing active vs. controlled RA. Results suggest that PT-based swollen joints were more c/w physician assessments than PT tender joint counts. Useful for telemed! #ACR20 @RheumNow @Janetbirdope #ABS0483 https://t.co/tozp9qBRXT
Dr. Rachel Tate uptoTate ( View Tweet)
We need to work together with our patients to ensure medication adherence during this pandemic.
1⃣30% of 734 pts on DMARDs changed their med use during COVID
2⃣Med change without physician guidance
3⃣Changes resulted in ⬆️steroid use
@RheumNow #ACR20 Abs#L05 https://t.co/n18zqed4wC
Robert B Chao, MD doctorRBC ( View Tweet)
#ACRbest Largest to date cohort study of pregnancies in women w/ ILD showed no maternal deaths suggesting that women w/ ILD may not need to avoid conception or terminate pregnancies, but pts w/ severe ILD were at higher risk for poor pregnancy outcomes. #Abst1446 @RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Dr Castillo-Bustamante presents a human otopathological study demonstrating RA involvement of ossicular joints of middle ear. Is there a functional effect on hearing? @rheumnow @bososhea #ACR20 Abstr#1759 https://t.co/iWlKs2KdOW
Richard Conway RichardPAConway ( View Tweet)