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Dr. Petri et al: Very ⬇ 25(OH)Vit D levels (<20ng/mL) is associated w/ renal insufficiency in SLE
🚨Levels >60ng/mL can ⬆renal insufficiency
This reinforces benefits of Vit.D supplementation (⬇ protnuria; immunomodulation)
@RheumNow #ACR20 abs1789 https://t.co/BJciK77fcp
sheila RHEUMarampa ( View Tweet)
SLR of frequency of visual ischaemia (VI) in relapse & follow-up of GCA
-VI >4weeks after GCA diagnosis is uncommon
-VI occurs in up to 3% patients with at least one relapse
-VI reported 3.5x more in RCTs vs retrospective studies
Abs#1929 #ACR20 @RheumNow
https://t.co/OztFRZ9VHc
Mrinalini Dey DrMiniDey ( View Tweet)
#mskus findings in pt w/normal muscle volume(ABC) vs. w/sarcopenia(DEF).
This Japanese study showed US of VL muscle is useful in discriminating RA pts w & w/o sarcopenia. @RheumNow #ACR20 abs1537 https://t.co/Gv7V0eebEt
sheila RHEUMarampa ( View Tweet)
@rheumnow #acr20 #absL03 RCDB PC ph2 trial TYK2i Deucravacitinib for PsA: ACR 20 at 16wk 6 mg 52.9% & 12 mg 62.7% vs PBO 31.8%. csDMARD & TNFi failure included. no serious infections, herpes zoster, opportunistic infections, or thrombotic events https://t.co/WVm4llPv5i
Olga Petryna DrPetryna ( View Tweet)
Abst#1720: Interesting results in predicting +CCP progression to IA: high BMI ⬆️ risk, EtOH ⬇️ risk, Cigarettes no effect but low smoking group. #ACR20 @RheumNow.
Eric Dein ejdein1 ( View Tweet)
@rheumNow #ACR20 #ABSL02 registry data: Pts on biologics more likely to Shield at Home during COVID 19 as opposed to non-biologic or no systemic Rx at all. Such stringent mitigation tactics may contribute to the reported lower risk of adverse COVID-19 outcomes in biologics Pts
Olga Petryna DrPetryna ( View Tweet)
Listen to part I of our #ACR20 Day 3 recap. Follow the link below or find us on Apple podcasts.
https://t.co/STTgimaUjp https://t.co/Zh2wZRnbyS
Links:
Dr. John Cush RheumNow ( View Tweet)
Retrosp study in France compared MRIs of 96 pts w/ SpA (65% w/ IBP) vs 104 w/o (25% w/ IBP):
- 65% of pts w/ SpA had bone marrow edema (BME) mainly in the iliac quad of intermed middle segment
- 20% w/o SpA had BME mainly in antero-middle quad. #Abst1535 #ACR2020 @RheumNow https://t.co/1ptGGUbUS4
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
~1/3 early RA patients report unacceptable pain w/in one year of diagnosis. 69% have pain w/ low inflammation. No objective baseline measures predict unacceptable pain. #ACR20 @RheumNow Abs#1716 We need to start pain approaches at time of diagnosis for all
Eric Dein ejdein1 ( View Tweet)
#AerobicExercise improves #Fatigue & #QualityofLife in women w/ #SLE
- ↓Fatigue & ↑overall health after exercise program
- No increase in #lupus activity
- Data may inform understanding of fatigue & exercise interventions in SLE
Abs#1838 #ACR20 @RheumNow
https://t.co/0YtYHrWp6t
Mrinalini Dey DrMiniDey ( View Tweet)
How often do you perform NFC in suspected SSc patients? @RheumNow #ACR20
sheila RHEUMarampa ( View Tweet)
@uptoTate @RheumNow It is only when I started working more closely with our rheum team to look at improving services did I realise how high no-shows are ! We have a 2yr waiting list so these appts are like gold dust. Unfortunately telemedicine not a viable option for your 1st rheum appt.
Wendy Costello wendycostello2 ( View Tweet)
Pulmonary disease and glucocorticoid usage risk factors for RA medication changes in first 3 month of #COVID19. Pts with higher reported disease activity more likely to make Rx changes #ACR20 @RheumNow. Abst#L05.
Eric Dein ejdein1 ( View Tweet)
No need to stop Tofa w/the flu?
👉Posthoc analysis 7964 Tofa pts over 14-15 flu seasons reported similar flu rates compared to ADA, MTX, PCB.
👉Tofa cont. in 70% pts; 28.8% stopped; mean days to resolution similar.
Abstr#L04 #ACR20 @rheumnow #ACRBest
https://t.co/rZXKRVl7uK
k dao KDAO2011 ( View Tweet)
Frequency and Anatomic Distribution of MRI Lesions in the Sacroiliac Joints of Healthy Subjects and Patients with Spondyloarthritis. Dr Hecquet. #ACR20 @RheumNow BME was seen in 65% patients with Spa and in 20% without spondyloarthritis predominantly in the antero-middle quadrant https://t.co/OUYz2FQ5Yp
Sole RetamozoSole ( View Tweet)
Accdg to this study, no association was found between IFN levels and cognitive function in SLE pts (even after considering factors like SLE dse duration)
Interesting! @RheumNow #ACR20 abs1788 @ZahiTouma https://t.co/F4j8H1CWJ9
sheila RHEUMarampa ( View Tweet)
Important work by Dr. Winthrop on influenza AEs in Tofacinitib patients - similar among 5mg/10mg BID, only 2 deaths/~500 cases, both with H1N1 and co-morbid RFs. Abst#L04 @RheumNow #ACR20 https://t.co/7MZYGv8W3i
Eric Dein ejdein1 ( View Tweet)
Do you have a problem with no-shows? #ABS1584 discusses telemedicine and care access during COVID-19. Case Western observed a 0% cancellation rate, <10% no-show rate, & 90% of scheduled telemed visits completed during COVID-19. #ACR20 #ACRbest @RheumNow https://t.co/uxzpfELDBG https://t.co/U2qrOTJZOq
Dr. Rachel Tate uptoTate ( View Tweet)
My axSpA patients often ask me whether whether it's the weight loss that matters, or just exercise.
Some answers from @rheum_cat - BMI itself does matter in AS. Another one chalked up for the obesity-related inflammasome!
#ACR20 ABST1883 @RheumNow https://t.co/oMOqA8ypTt
David Liew drdavidliew ( View Tweet)
Encouraging results on selective TK2 inhibitor in active PsA patients. ACR20 at week 16 of 53% and 63%, for low and high dose, compared to 32% placebo. NP, sinusitis, ha, rash most common AEs. Abst#L03 @RheumNow #ACR20 https://t.co/2UrOKFfnCL
Eric Dein ejdein1 ( View Tweet)