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Orthotics in Rheumatoid Arthritis
Orthotics are cost-effective, externally applied devices designed to stabilize the joints and provide a conservative measure to alleviate joint pain and improve function. Options include therapeutic shoes, shoe inserts, hand splints/braces, wrist support and finger splints. This article reviews some of the indications on the use of orthotics in patients with RA.
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German database shows since 2010, work participation has improved for rheum pts, reflected in higher employment, reduced absenteeism and less disability retirement. However, patients have not reached population employment rates. https://t.co/B8VKBgGNGe https://t.co/OOMNym3XrR
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Quick study of Henoch-Schönlein Purpura (HSP) in Children: An Overview https://t.co/n4V0XfMYbA https://t.co/zJ5WVjdfYe
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QD Clinic - An Undiagnosed Autoinflammatory Patient
Autoinflammatory or Still's disease - does this matter?
Features Dr. Jack Cush. QD Clinics - lessons from the clinic
Sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025
Register at https://t.co/2dcFVgu8z6… https://t.co/UimGBUZMeO https://t.co/fkAg9gK0Im
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Open label trial of starting MTX in 11 uncontrolled gout pts previously Rx w/ IV pegloticase (PEG 2-27x) showed if gout pts failed PEG monotherapy, only 1/11 (9%) showed a good response to adding MTX w/ PEG. MTX must be started w/ PEG initiation to work https://t.co/aoBtyIRbQe https://t.co/RNe03O6Z1N
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Palmar fasciitis & polyarthritis syndrome (PFPAS). JAMA case 50yoM w/ progressive hand swelling, stiffness, thickening, erythema, hepato-splenomegaly. Skin Bx dermal fibrous tissue. WBC 152k, LDH 889, lead to CML dx made by BM Fx (myeloid-erythroid ratio 21 w/ myeloblasts). +… https://t.co/xtHbzAioss https://t.co/RfMrfntFtb
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“Nothing in all the world is more dangerous than sincere ignorance and conscientious stupidity.”
- Martin Luther King
(Isnt that when someone says “I don’t know and I don’t care”) https://t.co/ZDwyyhX9XT
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post hoc analysis of 4 registration trials of pegloticase, show rates of MACE and Thromboembolic Events were Infrequent (<1.5%; 35.4 events/1000 PY), similar to general gout population (31.7 events/1000 person-years) https://t.co/v6ZqtL4yB2 https://t.co/NA0j20Oew2
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Worldwide, it is estimated that arthralgia treatments cost USD 4.7 Billion in 2024 and is estimated to reach USD 9.0 Billion by 2035. https://t.co/DYnbhpLAhr https://t.co/sKR8sssKNx
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“If I cannot do great things, I can do small things in a great way.”
- Martin Luther King https://t.co/2ixHPDdN1q
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Palmar fasciitis & polyarthritis syndrome (PFPAS). JAMA case 50yoM w/ progressive hand swelling, stiffness, thickening, erythema, hepato-splenomegaly. Skin Bx dermal fibrous tissue. WBC 152k, LDH 889, lead to CML dx made by BM Fx (myeloid-erythroid ratio 21 w/ myeloblasts). +… https://t.co/7gj3mvOSqs https://t.co/56tLd1jsNf
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Korean Biologics (KOBIO) registry showed SpA pts have higher risk of infection. 2,129 AS pts (7108 PY FU) most common was respiratory infx (26/1000 PY), followed by herpes zoster (6/1000 PY) Risk includes age, ischemic CV Dz, diabetes, CKD, peripheral arthritis.… https://t.co/0j1fH7OymW https://t.co/gqa1csylsn
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RA higher risk of Celiac Dz -- Rheumatic Dz administrative data review (2004–2013)compared 70,061 #RA w/ 276,895 controls, median F/U 9 yrs. (IQR 9–9). Celiac Prevalence higher in RA (171/70,061 = 0.24% vs 398/276895 = 0.14%; p < 0.001), more so in females w/ RA… https://t.co/SayZYvkZpV https://t.co/fcuyJ5sFk0
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Systematic review of 14 studies using administrative/med. records data on >130 million people & 1 million dementia cases, finds the risk of Alzheimers/Dementia reduced w/ Antimicrobials, vaccines & NSAID antiinflammatories (but incr w/ DM drugs, vitamins, antipsychotics)… https://t.co/p79s5Pw4k2 https://t.co/9DO1WO2NuG
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Congratulations to Jennifer Anolik, MD, PhD, being named chief of the Allergy, Immunology & Rheumatology at the Univ. of Rochester Medical Center; where she is also Assoc Chair of research & professor of Medicine, Pathology, Microbiology and Immunology, and director of the… https://t.co/jvRiZZ6u1q https://t.co/N2nFp8w6Yx
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“Injustice anywhere is a threat to justice everywhere.” - Martin Luther King https://t.co/y3UDZP8uTN
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Fallen Angels (1.17.2025)
Dr. Jack Cush reviews the news and journal reports from the past week on https://t.co/V10S4oVFsv; and pays homage to colleagues who passed away in 2024.
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We must learn to live together as brothers or perish together as fools.
Martin Luther King Jr. (1929 - 1968) https://t.co/3mWHhPY5rH
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"I'd rather be a failure at something I love than a success at something I hate."
- Martin Luther King Jr. https://t.co/E2f5mEV9Jx
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Challenging the status quo is difficult, and worth it. Happy Birthday.
-Seth Godin https://t.co/xVgdC8wJnD https://t.co/Mdtm9XwOs9
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