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Autoimmune Risk of Death Up during COVID

d Jack Cush, MD

A population-based study in the UK shows that patients with rare autoimmune rheumatic diseases (RAIRD) were 44% more likely to die during the 2020 COVID-19 pandemic (March - April) compared to either the general population or their pre-COVID risk.

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USPSTF - No Need to Screen for Vitamin D Deficiency

d Jack Cush, MD

JAMA has published the new recommendation from the US Preventive Services Task Force (USPSTF) stating that screening for vitamin D deficiency is unnecessary and unwarranted in asymptomatic adults.

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NICE Guidelines on Chronic Pain Management

d Jack Cush, MD

In the United Kingdom, where it is estimated that chronic pain affects one‑third to one‑half of the population, NICE (National Institute for Health and Care Excellence) has recently released an updated guideline on the management of chronic pain for people aged 16 years and over.

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Sinusitis Activity Linked to Brain Dysfunction

d Jack Cush, MD

Have you wondered why fibromyalgia, fatigue or cognitive dysfunction often co-associate with chronic sinusitis?

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IL-23 Targeting for Enthesitis in Psoriatic Arthritis

d MedPage Today

Treatment with guselkumab (Tremfya) was effective in resolving enthesitis among patients with psoriatic arthritis (PsA), a post-hoc analysis of two phase III trials found.

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"Don't check antibodies post vaccination! Most lab assays test anti-nucleocapsid antibodies from the virus and not the antibodies to the spike protein. Also we do not have data at what antibody level is protective or not protective. - Dr. J Curtis #RNL2021 @RADoctor "

Dr. John Cush RheumNow ( View Tweet)

Smoking and RA are closely related. 50% of establish RA pts higher rate of smoking Smoking cessation - lowers RA disease activity #RNL2021

Dr. John Cush RheumNow ( View Tweet)

Study of 2,842 participants in Osteoarthritis Initiative shows that a Western diet is associated with an increased risk of knee OA (HR =1.69), while a more prudent diet reduced risk of knee OA (HR = 0.70). 30% risk is mediated by high BMI https://t.co/24Dbwy9eJ5

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Dr. John Cush RheumNow ( View Tweet)

News Feature: Sinusitis Activity Linked to Brain Dysfunction Have you wondered why fibromyalgia, fatigue or cognitive dysfunction often co-associate with chronic sinusitis? https://t.co/Ow993w5Jb9 https://t.co/mYYDkDuJTv

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Dr. John Cush RheumNow ( View Tweet)
Calcinosis is associated with these autoantibodies - NXP-2, anti-PM/SCL and MDA-5 https://t.co/ORA2y1BWgn

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Dr. John Cush RheumNow ( View Tweet)

“Send a photo with the skin biopsy” - advice to rheumatologists by a dermatopathologist to help with path interpretation. #RNL2021 Great #RNL2021 notes from Dr. Kathryn Dao @KDAO2011

Dr. John Cush RheumNow ( View Tweet)

Can Multiple Sclerosis and RA Coexist? What Drugs can be used? https://t.co/PYFQI7vn3M https://t.co/UQplGREDjf

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Dr. John Cush RheumNow ( View Tweet)
News Feature: IL-23 Targeting for Enthesitis in Psoriatic Arthritis Treatment with guselkumab (Tremfya) was effective in resolving enthesitis among patients with psoriatic arthritis (PsA), a post-hoc analysis of two phase III trials found. https://t.co/a6ypaa6Zxb https://t.co/zdRpZWIPAt

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Dr. John Cush RheumNow ( View Tweet)
#RNL2021 notes from Dr. Rachel Tate ( @uptoTate ) Clinical pearl: Bisphosphonates can cause posterior iritis (consider this in patients with negative labs and long term use of bisphosphonates.) Dr. Wang #RheumNow

Dr. John Cush RheumNow ( View Tweet)

Artificial intelligence study shows neural networks can be trained to detect radiographic sacroiliitis on pelvic Xrays and achieve expert-level detection of definite radiographic sacroiliitis & could improve diagnostic accuracy at non-specialised sites https://t.co/oLNzWjHjrw

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News Feature: Low Risk of Malignancy with Secukinumab Analysis of ongoing safety from the SEC drug development program shows a low risk for malignancy in SEC patients treated for up to five years for either psoriasis, PsA or AS. https://t.co/tf1lWa03tF https://t.co/Ad1fOJZv4c

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Dr. John Cush RheumNow ( View Tweet)
In millions with hand OA, the thumb base (CMC1) is the most affected joint. metanalysis of 16 studies shows Xray CMC1 OA is more prevalent in females and is strongly associated with age. https://t.co/mNeXbWHdwa

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Dr. John Cush RheumNow ( View Tweet)

News Feature: DMARD Dropouts During COVID-19 Rheumatologists are still seeing the consequences of COVID, with many patients avoiding usual care, follow-up visits, routine lab testing and with many self-stopping their antirheumatic meds. https://t.co/gwtfvR9o53 https://t.co/92APJKUs0W

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Dr. John Cush RheumNow ( View Tweet)
Since the COVID vaccine rollout, more people have been eligible to receive the vaccine. However, not everyone chooses to get one. I have heard many reasons from my patients who are vaccine hesitant. Read more from Dr. Kathryn Dao ( @KDAO2011 ) https://t.co/f5gwBICEGy https://t.co/XgW6wVgo0F

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Dr. John Cush RheumNow ( View Tweet)
Hopkins Lupus Cohort (1168 patients) followed 24 months shows disease activity (measured by SELENA SLEDAI) increased risk of death (HR=1.22), renal damage (HR=1.24) & CV Dz (HR=1.17); But HCQ reduced death (HR=0.46) https://t.co/zBfitPV5Bl

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