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Don’t use ‘biopsy-proven’ to label sarcoidosis; use ‘biopsy supported’ as there are many causes of granulomatous inflammation. It’s happened to one of my pts who was diagnosed with “biopsy-proven” sarcoidosis - she actually had CVID with GLILD. #ACRReview #ACR24 https://t.co/it41va1K6g
TheDaoIndex KDAO2011 ( View Tweet)
What is Osteoarthritis? A downloadable patient education page from JAMA. https://t.co/gocsQizJUh https://t.co/4bBuNUAYlR
Dr. John Cush RheumNow ( View Tweet)
Survey of 779 RA pts in the National Rheumatoid Arthritis Society. Respondents were 95% Caucasian in their 50s with menopause in their 40s. 80% responded that their arthritis was worse during the menopause with 10% being much worse. https://t.co/NqZXK1lLQe https://t.co/k59HD5bKrd
Dr. John Cush RheumNow ( View Tweet)
Early RA Journey - Patient Perspectives and Uncertainties
Canadian early RA (ERA) patients were interviewd to depict their perspectives from onset and diagnosis to referral and care. This report highlights the importance of patient pain and primary care physician (PCP) intake… https://t.co/gwNL7iZIT5 https://t.co/SL0Jw0H8f6
Dr. John Cush RheumNow ( View Tweet)
Late-onset axSpA (LOS) is more likely to have peripheral arthritis. but less HLA-B27 & +FHx of AS/SpA. Portugese study of 2165 axSpA pts. 273 LOS (Sx onset >45 yrs; mean 51yrs; 55% men) had less B27 (51% vs 65%), +FHx (8% vs 14%), inflam LBP (81% vs 88%), Uveitis (13% vs 20%)… https://t.co/DgRUt1ejxT https://t.co/dGX2bfKhnK
Dr. John Cush RheumNow ( View Tweet)
AMA report says..... " More than one in three physicians, 34 percent, have had a medical liability lawsuit filed against them at some point in their careers"
- Nearly half of physicians >55 have been sued (vs 6% in MDs <40yrs)
- Female physicians are less likely to be sued than… https://t.co/hIUH7Tx85L https://t.co/V2sHyac3XH
Dr. John Cush RheumNow ( View Tweet)
NHANES study of 11264 adolescents (12–17 yrs) found Hyperuricemia (≥ 5.5 mg/dL) in 33%, (51% males, 13% females) and was more prevalent with obesity and in non-Hispanic Asians https://t.co/rwUt1Cgg9b https://t.co/dFr1LeX0nC
Dr. John Cush RheumNow ( View Tweet)
Peptic ulcer disease is still assoc w/ signif. hospitalization & mortality (10K deaths in USA/Yr). PUD affects 10% of outpts w/ Upper GI pain. 42% are due to H.pylori, 36% from ASA NSAIDs. Complications bleeding (73%), perforation (9%), pyloric obstruction (3%)- JAMA review… https://t.co/1bgagFVlYN https://t.co/8i2j3r1puf
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Full read JAMA ILD Review article. ILD= 33% idiopathic (IPF) + 15% hypersensitivity pneumonitis + 25% from CTD.
30% of ILD has cough
Chest CT 91% sensitive, 71% specific
5% decr in FVC/12 mos assoc w/ 2-fold incr in mortality
Rx options nintedanib or pirfenidone, TCZ, MMF, RTX… https://t.co/9pET497zjC https://t.co/P8XVlVmmLd
Dr. John Cush RheumNow ( View Tweet)
211 SSc patients, men and younger women, have lower BMD than the population (Osteopenia in 52% & 16.5% osteoporosis; P=0.001). Low BMD in women assoc w/ Finger ulcers, diffuse involvement, older age, & being post-menopausal https://t.co/qyvEJoIbKH https://t.co/zj2Fn1oU5n
Dr. John Cush RheumNow ( View Tweet)
Virtual Yoga Effective in Chronic Low Back Pain
A randomized trial of 140 adults with chronic low back pain (CLBP) demonstrated that virtual yoga instruction resulted in significant improvements in CLBP patients compared to the wait-list control group.
https://t.co/BuYWb1wCXG https://t.co/tQawiZFIJv
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New download available!
Substitute Inflammatory Measures
https://t.co/FiZSvvl5DA https://t.co/QwVefFLcHO
Dr. John Cush RheumNow ( View Tweet)
Overlap Syndrome with ILD
https://t.co/4CG6CU4g2r https://t.co/EFjRrblepN
Dr. John Cush RheumNow ( View Tweet)
Long Covid Defined
While COVID-19 has infected over 7 million worldwide, it is estimated that 7% of adults (and >1% of children) or 15 to 20 million Americans have developed long COVID, a chronic condition with systemic and often disabling symptoms.
https://t.co/9njt8Kqe7P https://t.co/2V5OVlUrfQ
Dr. John Cush RheumNow ( View Tweet)
Advances in the treatment of autoimmune hepatitis
Autoimmune hepatitis (AIH) is a chronic, progressive liver disease caused by immune system dysregulation that targets the liver. If untreated, AIH can lead to severe complications, including cirrhosis and liver failure.… https://t.co/6GtWZ8tDDv https://t.co/YuJrcOyaGP
Dr. John Cush RheumNow ( View Tweet)
Literature review of the treatment of IgA Vasculitis (Henoch–Schönlein Purpura) suggests:
- Glucocorticoids are 1st -line therapy, esp if severe
- For minor HSP: colchicine, dapsone, & methotrexate may be useful
- Also studied cyclosporine A, tacrolimus, MMF… https://t.co/ZoZX3kyHvo https://t.co/dS82ekuEkv
Dr. John Cush RheumNow ( View Tweet)
Susac syndrome is a rare disease of young women characterised by microvessel occlusive Dz limited to the brain, retina, and inner ear. Rx is steroids, but Lancet Rheumatol Review of Rx shows no benefit of immunosuppressive Rx https://t.co/FvJa9OZLWL https://t.co/NVS0I3ofm8
Dr. John Cush RheumNow ( View Tweet)
EULAR Review of Lifestyle Improvements for Rheumatic Patients
A EULAR taskforce evaluated lifestyle behaviors' effects on rheumatic and musculoskeletal diseases (RMDs), finding moderate evidence for minor benefits from certain dietary components. However, high-level evidence on… https://t.co/maaz8W5IUT https://t.co/QiE6Oo1MzX
Dr. John Cush RheumNow ( View Tweet)
Weight Loss Drugs and the Loss of Skeletal Muscle Mass
A commentary in The Lancet emphasizes the importance of skeletal muscle mass in medically induced weight loss, especially with the use of GLP-1 receptor agonists. While these drugs are effective for obesity treatment, there… https://t.co/8AOgDUajw6 https://t.co/0vntwZSpLy
Dr. John Cush RheumNow ( View Tweet)
Survey of UK Rheumatology pts (n 876 found 55% take daily supplements costing £10 to £200 per month (most common: vit D, C, B complex, MVI Omega 3/6). 82% take Prescription, OTC, or non-prescription pain meds, 13% sleep aids. Half of NSAID pts also take OTC supplements… https://t.co/VpMG9SiE1E https://t.co/SJYUfogeVJ
Dr. John Cush RheumNow ( View Tweet)
