Normal weight PsA pts had numerically better PsAID and PGA scores than obese PsA pts when treated with SEC. SEC was effective in all BMI subgroups. Abs 0395 #ACR22 @RheumNow https://t.co/oBSsuJKRem https://t.co/BhybOk76Gr

• How Does Body Mass Index Affect Secukinumab Treatment Outcomes and Safety in Pa…

Werth et al. Lenabasum phase 3 trial indermatomyositis. Primary endpoint (TIS week 28) not met. Subgroup analysis suggest small effect on muscle and modest effect on skin disease @rheumnow #ACR22 Abstr#0173 https://t.co/qhL2PcTcHV https://t.co/uR8Bg5awiK

• Cutaneous Manifestations, Clinical Trials, Safety Efficacy and Safety of Lenaba…

Vikse et al. Norwegian case series of 40 patients treated with RTX for IgG4-RD. Efficacy across phenotypes 80-100% for improvement but only 45-78% for remission. @rheumnow #ACR22 Abstr#0147 https://t.co/J7b47ywbt0 https://t.co/pfhOIG5qXk

• Rituximab in IgG4-Related Diseae: An Open-Label Non-Randomized Observational St…

This work can lay foundation to so much more! #ArtificialIntelligence and #naturallanguageprocessing on Facebook private #gout groups - Mental health mentioned in 4% of all posts/comments - primary care asso with “trust” and urgent care with “fear” @RheumNow #ACR22 abst#0201 https://t.co/fSuOeNGWvg

Liew @rheum_cat et al. No evidence of cardioprotective effect of early initiation of TNFi in AxSpA. In fact seemed to be associated higher risk! CVD (HR 1.17), stroke (HR 1.24), and MACE (HR 1.22) @rheumnow #ACR22 Abstr#0415 https://t.co/a9lpxQuMB9 https://t.co/GdGfYxcAH6

• The Association of Early TNF Inhibitor Use with Incident Cardiovascular Events …

Germano et al. Physical exam of temporal arteries predictive of TAB+. Decreased pulse nad thickened artery most useful @rheumnow #ACR22 Abstr#0483 https://t.co/NGvu8pMiaj https://t.co/F0Y9oy0hWy

• Giant Cell Arteritis: Physical Examination of the Superficial Temporal Arteries…

Merkel. Vilobelimab in AAV. C5a mab. Phase 2. Given with RTX/CYC. Various steroid regimes (none, reduced, standard). Not powered for non-inferiority but encouraging results. Makes sense, this is the same pathway as avacopan @RheumNow #ACR22 Abstr#0524 https://t.co/HY5i6wqnjI https://t.co/CTXUdP3PZV

• A Randomized, Double-Blind, Phase II Study of Glucocorticoid Replacement by Vil…

Exciting development in Lupus! Change in urinary biomarkers (CD163 and MMR) better predictor than proteinuria for lupus nephritis treatment response. Larger longitudinal studies needed. Abs#0536 @RheumNow #ACR22 #ACRBest https://t.co/MLSWdl0xUo

Bandeira et al. When to look for cardiac involvement in IIM. Lung involvement and anti-SRP abs both ORs of >7 main warning signs @rheumnow #ACR22 Abstr#0171 https://t.co/02cKN23Ufq https://t.co/3NioXUwVPM

• Cardiac Involvement in Idiopathic Inflammatory Myopathies: When Should We Look …

Pearl - ‘Three Useful Ophthalmologic Acronyms’ with Dr. John Stone KP- Keratic Precipitates PUK- Peripheral Ulcerative Keratitis IOI- Idiopathic Orbital Inflammation Add PUK to the Rheum Emergencies. Seen in #RA and #AAV @RheumNow #ACR22 https://t.co/GUc9boY0WV

Yang et al. Incidence and risk factors for cutaneous lupus becoming SLE. 11.8% transitioned after 20 years. Age<40 (HR 3.25), in first 10 years after skin lupus diagnosis, SCLE>DLE (HR 0.28)/others (HR 0.11) @rheumnow #ACR22 Abstr#0338 https://t.co/IxVS4mOveD https://t.co/3VeQ8WPQtU

• Transitioning from Cutaneous to Systemic Lupus Erythematosus: An Analysis of In…

Clinical pearl! Talk to your PsA pts about sleep. Abs 0387 shows circular relationship between sleep quality, emotional disorders, and activity in these patients. Emotional factors more relevant than inflammatory factors on sleep quality. #ACR22 @RheumNow https://t.co/0p5hfNHM91 https://t.co/XrMTmsoMYR

• Sleep Quality in Patients with Psoriatic Arthritis and Its Relationship with Ac…

Patel @NaomiRheumMD et al. Baseline GTI in GCA in GiACTA. Blood pressure and glucose tolerance biggest contributors. Higher in relapsing 122.5 vs 98.9. BMI and neuropsych higher in relapsing. @rheumnow #ACR22 Abstr#0460 https://t.co/dSIt1xEOva https://t.co/2tAkgVEEeA

• Baseline Glucocorticoid Toxicity in the Treatment of Giant Cell Arteritis: A Po…

Patel @NaomiRheumMD et al. HbA1c in GiACTA. Tocilizumab assoc HbA1c reduction independent of steroids. Daily steroid dose assoc HbA1c @rheumnow #ACR22 Abstr#0461 https://t.co/9Nbewrpww8 https://t.co/NyeTyWICF6

• The Effects of Daily Prednisone and Tocilizumab on Hemoglobin A1c During the Tr…

Clinical pearl! Patient-reported treatment success in PsA assoc'd w/ control of arthritis, dactylitis, psoriasis, and health-related QoL. Top 3 pt-reported reasons for tx failure were pain, psoriasis and fatigue. Abs0393 #ACR22 @RheumNow https://t.co/F9RNI7EXcL https://t.co/7DcLaqUqnm

• Are We Meeting Patients&#039; Treatment Goals with Guideline-Based Therapy for …